In general, when looking for the cheapest flight to Guayaquil, try to choose a flight departing in March for the best deal.
Most flyers found that booking flight tickets 15 days in advance of their planned departure date is, on average, the best time to get cheap flights to Guayaquil.
From most locations, the cheapest flights to Guayaquil are found on a Sunday. Booking a Wednesday departure is usually the most expensive.
Typically, cheap prices to Guayaquil are most often found for morning flights. Cheap prices are less likely for evening flights.