Cheap flights from Amsterdam to Panama City from £350

If you aren’t able to travel to Panama City during the month of August, then flying in January is also cheap. Prices for this month can be found on momondo for an average of £593.

You are more likely to see cheaper flights to Panama City from Amsterdam when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around £643 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Amsterdam for as low as £546 on momondo.

There is only 1 cabin class available to choose from on Amsterdam to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

As of April 2026, prices for Amsterdam to Panama City flights are approximately 64% more expensive when compared to flights at the same time last year.

Historically, on average around 24% of flights between Amsterdam and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 133 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights departing in the early afternoon have, in the past, seen delays more frequently in comparison.

Sunday is statistically the day of the week that experiences the fewest delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, KLM have had the fewest delays on this route over the last 12 months, with about 24% of their flights experiencing any sort of delay.

3 flights are operational daily from Amsterdam to Panama City as of April 2026. The most popular departure time for this route is 12:00, with 100% of flights per day taking off in the afternoon.

As of April 2026, there are 21 flights per week flying from Amsterdam to Panama City. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.