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Cheap flights from Madrid to Santa Cruz de la Sierra from £311

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 25/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Madrid to Santa Cruz de la Sierra

Cheap return flights

Avianca Logo
17:30 - 01:50MAD-VVI
38h 20m1 stop
Avianca Logo
02:50 - 11:10VVI-MAD
26h 20m1 stop
£649Avianca
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Thu, 25 Sep - Thu, 9 Oct
Avianca Logo
10:50 - 02:35MAD-VVI
20h 45m1 stop
Avianca Logo
03:40 - 13:25VVI-MAD
28h 45m1 stop
£664Avianca
Find Deal
Tue, 10 Feb - Mon, 9 Mar
Avianca Logo
06:35 - 02:35MAD-VVI
25h 00m1 stop
Avianca Logo
03:40 - 23:20VVI-MAD
14h 40m1 stop
£692Avianca
Find Deal
Mon, 24 Nov - Sat, 24 Jan
Avianca Logo
01:20 - 02:35MAD-VVI
30h 15m1 stop
Avianca Logo
03:40 - 23:20VVI-MAD
14h 40m1 stop
£723Avianca
Find Deal
Mon, 9 Feb - Mon, 9 Mar
Avianca Logo
06:35 - 02:35MAD-VVI
25h 00m1 stop
Avianca Logo
03:40 - 13:25VVI-MAD
28h 45m1 stop
£747Avianca
Find Deal
Thu, 25 Dec - Sat, 24 Jan
Avianca Logo
10:50 - 02:35MAD-VVI
20h 45m1 stop
Avianca Logo
03:40 - 23:20VVI-MAD
14h 40m1 stop
£751Avianca
Find Deal
Fri, 21 Nov - Thu, 22 Jan
Avianca Logo
01:20 - 02:35MAD-VVI
30h 15m1 stop
Avianca Logo
03:40 - 23:20VVI-MAD
14h 40m1 stop
£775Avianca
Find Deal
Thu, 20 Nov - Thu, 22 Jan
Avianca Logo
09:40 - 01:50MAD-VVI
22h 10m1 stop
Avianca Logo
02:50 - 14:05VVI-MAD
29h 15m1 stop
£794Avianca
Find Deal
Fri, 26 Sep - Wed, 8 Oct
United Airlines Logo
11:15 - 22:25MAD-VVI
41h 10m2 stops
United Airlines Logo
01:09 - 08:05VVI-MAD
24h 56m2 stops
£801United Airlines
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Fri, 26 Sep - Sat, 4 Oct
United Airlines Logo
11:15 - 22:25MAD-VVI
41h 10m2 stops
United Airlines Logo
01:09 - 08:05VVI-MAD
48h 56m2 stops
£889United Airlines
Find Deal
Fri, 26 Sep - Sat, 11 Oct

United Airlines flights from Madrid to Santa Cruz de la Sierra

Our best United Airlines deals on Madrid to Santa Cruz de la Sierra flight tickets
United Airlines
26 Sept
MAD11:15Madrid Barajas
41h 10m
2 stops
VVI22:25Santa Cruz de la Sierra Viru Viru Intl
4 Oct
VVI01:09Santa Cruz de la Sierra Viru Viru Intl
24h 56m
2 stops
MAD08:05Madrid Barajas
£801
Find similar
United Airlines
23 Sept
MAD11:15Madrid Barajas
41h 10m
2 stops
VVI22:25Santa Cruz de la Sierra Viru Viru Intl
12 Oct
VVI01:09Santa Cruz de la Sierra Viru Viru Intl
24h 56m
2 stops
MAD08:05Madrid Barajas
£802
Find similar
United Airlines
26 Sept
MAD11:15Madrid Barajas
41h 10m
2 stops
VVI22:25Santa Cruz de la Sierra Viru Viru Intl
11 Oct
VVI01:09Santa Cruz de la Sierra Viru Viru Intl
48h 56m
2 stops
MAD08:05Madrid Barajas
£889
Find similar

Avianca flights from Madrid to Santa Cruz de la Sierra

Our best Avianca deals on Madrid to Santa Cruz de la Sierra flight tickets
Avianca
25 Sept
MAD17:30Madrid Barajas
38h 20m
1 stop
VVI01:50Santa Cruz de la Sierra Viru Viru Intl
9 Oct
VVI02:50Santa Cruz de la Sierra Viru Viru Intl
26h 20m
1 stop
MAD11:10Madrid Barajas
£649
Find similar
Avianca
10 Feb
MAD10:50Madrid Barajas
20h 45m
1 stop
VVI02:35Santa Cruz de la Sierra Viru Viru Intl
9 Mar
VVI03:40Santa Cruz de la Sierra Viru Viru Intl
28h 45m
1 stop
MAD13:25Madrid Barajas
£664
Find similar
Avianca
24 Nov
MAD06:35Madrid Barajas
25h 00m
1 stop
VVI02:35Santa Cruz de la Sierra Viru Viru Intl
24 Jan
VVI03:40Santa Cruz de la Sierra Viru Viru Intl
14h 40m
1 stop
MAD23:20Madrid Barajas
£692
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Madrid to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 16 September 2025.
Use the filters below to find and compare flights from Madrid to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Thu 25/9

17:30-01:50

1 stop38h 20m

Santa Cruz de la Sierra Viru Viru Intl

Thu 9/10

02:50-11:10

1 stop26h 20m

£649

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 10/2

10:50-02:35

1 stop20h 45m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/3

03:40-13:25

1 stop28h 45m

£664

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 24/11

06:35-02:35

1 stop25h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sat 24/1

03:40-23:20

1 stop14h 40m

£692

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 9/2

01:20-02:35

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/3

03:40-23:20

1 stop14h 40m

£723

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Thu 25/12

06:35-02:35

1 stop25h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sat 24/1

03:40-13:25

1 stop28h 45m

£747

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 21/11

10:50-02:35

1 stop20h 45m

Santa Cruz de la Sierra Viru Viru Intl

Thu 22/1

03:40-23:20

1 stop14h 40m

£751

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Thu 20/11

01:20-02:35

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Thu 22/1

03:40-23:20

1 stop14h 40m

£775

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 26/9

09:40-01:50

1 stop22h 10m

Santa Cruz de la Sierra Viru Viru Intl

Wed 8/10

02:50-14:05

1 stop29h 15m

£794

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 26/9

11:15-22:25

2 stops41h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/10

01:09-08:05

2 stops24h 56m

£801

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 26/9

11:15-22:25

2 stops41h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/10

01:09-08:05

2 stops48h 56m

£889

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from Madrid to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Madrid and Santa Cruz de la Sierra?

What is the cheapest month to fly to Santa Cruz de la Sierra?

The month of May is, on average, the cheapest month to fly to Santa Cruz de la Sierra from Madrid, with most prices found around £578. If you aren’t able to travel during the month of May, then book flights to Santa Cruz de la Sierra from Madrid during March instead. Flights to Santa Cruz de la Sierra in March, while not as cheap as those in May, still average around £637.

What is the cheapest day to depart on your flight to Santa Cruz de la Sierra?

The cheapest day to depart on your flight to Santa Cruz de la Sierra is on a Friday when prices can be found for as low as £596. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Santa Cruz de la Sierra is Thursday, with ticket prices averaging around £1,056.

What is the cheapest time of day to depart on your flight to Santa Cruz de la Sierra?

The cheapest time of day to fly to Santa Cruz de la Sierra is in the afternoon when flights can be purchased for as low as £646. In contrast, the most expensive time of day to depart to Santa Cruz de la Sierra is in the morning when prices are around £945.

What is the cheapest Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flight route?

Fly from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl for the best Madrid Barajas - Santa Cruz de la Sierra Viru Viru Intl flight prices

How far in advance should I book a flight to Santa Cruz de la Sierra?

You are more likely to see cheaper flights to Santa Cruz de la Sierra from Madrid when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Cruz de la Sierra for around £765 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Cruz de la Sierra from Madrid for as low as £616 on momondo.

What cabin class options are available on Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flights?

There are 2 cabin classes available to choose from on Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Madrid to Santa Cruz de la Sierra flights?

You could potentially save up to 62% on your flight if you consider stops on a Madrid to Santa Cruz de la Sierra flight.

How have Madrid to Santa Cruz de la Sierra flight prices changed over time?

As of September 2025, prices for Madrid to Santa Cruz de la Sierra flights are approximately 7% cheaper when compared to flights at the same time last year.

When to book flights from Madrid to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Madrid to Santa Cruz de la Sierra (MAD to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Santa Cruz de la Sierra

Best price found

£1,911

Direct flights

None
The best flight deal from Madrid to Santa Cruz de la Sierra found on momondo in the last 72 hours is £1,911
There are no direct flights from Madrid to Santa Cruz de la Sierra. There are no popular flight routes from Madrid to Santa Cruz de la Sierra.
Search flight deals

  • How far is Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The straight-line distance from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl is 5537.8 mi. Typically, this will take 20h 45m by plane in normal conditions.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The travel and health documents required for your trip to Santa Cruz de la Sierra Viru Viru Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Cruz de la Sierra Viru Viru Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Madrid to Santa Cruz de la Sierra?

  • What is the most popular airline from Madrid to Santa Cruz de la Sierra?

Best airlines flying from Madrid to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Madrid to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
BoAPriceFrom £546Free CancellationRating
6.8
136 reviews
Search BoA flights
IberiaPriceFrom £547Free CancellationRating
7.0
2,924 reviews
Search Iberia flights
AviancaPriceFrom £556Free CancellationRating
6.7
2,435 reviews
Search Avianca flights

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Santa Cruz de la Sierra?

Finding the right flight to Santa Cruz de la Sierra from Madrid is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Cruz de la Sierra quick and easy, saving you time and money.

Can I find flights from Madrid to Santa Cruz de la Sierra with flexible booking policies on momondo?

All flight searches from Madrid to Santa Cruz de la Sierra on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Madrid to Santa Cruz de la Sierra?

Once all potential Madrid to Santa Cruz de la Sierra flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Madrid to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra from Madrid and alert you when they change.

An easier way to manage your Santa Cruz de la Sierra trip

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