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Cheap flights from Madrid to Santa Cruz de la Sierra from £369

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 31/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Madrid to Santa Cruz de la Sierra

Cheap return flights

Enter your travel dates to find the best prices.
Avianca Logo
01:20 - 02:35
MAD
-
VVI
30h 15m1 stop
Avianca Logo
02:55 - 14:05
VVI
-
MAD
29h 10m1 stop
£722Avianca
Thu, 19 Mar - Mon, 20 Apr
Avianca Logo
01:20 - 02:35
MAD
-
VVI
30h 15m1 stop
Avianca Logo
03:40 - 13:25
VVI
-
MAD
28h 45m1 stop
£778Avianca
Sun, 25 Jan - Mon, 9 Feb
Avianca Logo
07:40 - 02:35
MAD
-
VVI
23h 55m2 stops
Avianca Logo
02:55 - 07:40
VVI
-
MAD
22h 45m1 stop
£790Avianca
Fri, 20 Mar - Mon, 20 Apr
Avianca Logo
07:05 - 02:35
MAD
-
VVI
24h 30m2 stops
Avianca Logo
02:55 - 11:10
VVI
-
MAD
26h 15m1 stop
£791Avianca
Fri, 20 Mar - Mon, 20 Apr
Avianca Logo
07:05 - 01:50
MAD
-
VVI
24h 45m2 stops
Avianca Logo
02:55 - 07:40
VVI
-
MAD
22h 45m1 stop
£792Avianca
Sun, 10 May - Sat, 23 May
Avianca Logo
09:40 - 01:50
MAD
-
VVI
22h 10m1 stop
Avianca Logo
02:55 - 13:55
VVI
-
MAD
29h 00m2 stops
£794Avianca
Mon, 13 Apr - Sat, 2 May
Avianca Logo
06:35 - 02:35
MAD
-
VVI
25h 00m1 stop
Avianca Logo
03:40 - 08:50
VVI
-
MAD
24h 10m1 stop
£808Avianca
Thu, 29 Jan - Sun, 22 Feb
Avianca Logo
07:05 - 02:35
MAD
-
VVI
24h 30m2 stops
Avianca Logo
03:40 - 13:25
VVI
-
MAD
28h 45m1 stop
£815Avianca
Tue, 10 Feb - Mon, 9 Mar
Avianca Logo
07:05 - 02:35
MAD
-
VVI
24h 30m2 stops
Avianca Logo
03:40 - 13:25
VVI
-
MAD
28h 45m1 stop
£816Avianca
Tue, 10 Feb - Mon, 9 Mar
Avianca Logo
13:10 - 01:50
MAD
-
VVI
18h 40m1 stop
Avianca Logo
02:55 - 13:55
VVI
-
MAD
29h 00m2 stops
£818Avianca
Mon, 13 Apr - Sat, 9 May

Avianca flights from Madrid to Santa Cruz de la Sierra

Our best Avianca deals on Madrid to Santa Cruz de la Sierra flight tickets
Avianca
19 Mar
MAD01:20Madrid Barajas
30h 15m
1 stop
VVI02:35Santa Cruz de la Sierra Viru Viru Intl
20 Apr
VVI02:55Santa Cruz de la Sierra Viru Viru Intl
29h 10m
1 stop
MAD14:05Madrid Barajas
£722
Find similar
Avianca
25 Jan
MAD01:20Madrid Barajas
30h 15m
1 stop
VVI02:35Santa Cruz de la Sierra Viru Viru Intl
9 Feb
VVI03:40Santa Cruz de la Sierra Viru Viru Intl
28h 45m
1 stop
MAD13:25Madrid Barajas
£778
Find similar
Avianca
20 Mar
MAD07:05Madrid Barajas
24h 30m
2 stops
VVI02:35Santa Cruz de la Sierra Viru Viru Intl
20 Apr
VVI02:55Santa Cruz de la Sierra Viru Viru Intl
26h 15m
1 stop
MAD11:10Madrid Barajas
£791
Find similar

LATAM Airlines flights from Madrid to Santa Cruz de la Sierra

Our best LATAM Airlines deals on Madrid to Santa Cruz de la Sierra flight tickets
LATAM Airlines
2 Feb
MAD12:15Madrid Barajas
21h 20m
2 stops
VVI04:35Santa Cruz de la Sierra Viru Viru Intl
26 Feb
VVI05:25Santa Cruz de la Sierra Viru Viru Intl
19h 15m
1 stop
MAD05:40Madrid Barajas
£1,054
Find similar
LATAM Airlines
27 Dec
MAD13:10Madrid Barajas
20h 25m
1 stop
VVI04:35Santa Cruz de la Sierra Viru Viru Intl
15 Jan
VVI05:25Santa Cruz de la Sierra Viru Viru Intl
25h 10m
2 stops
MAD11:35Madrid Barajas
£1,228
Find similar
LATAM Airlines
27 Dec
MAD11:05Madrid Barajas
27h 51m
2 stops
VVI09:56Santa Cruz de la Sierra Viru Viru Intl
15 Jan
VVI05:25Santa Cruz de la Sierra Viru Viru Intl
25h 10m
2 stops
MAD11:35Madrid Barajas
£1,374
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Madrid to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 18 December 2025.
Use the filters below to find and compare flights from Madrid to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Thu 19/3

01:20-02:35

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Mon 20/4

02:55-14:05

1 stop29h 10m

£722

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 25/1

01:20-02:35

1 stop30h 15m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/2

03:40-13:25

1 stop28h 45m

£778

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 20/3

07:40-02:35

2 stops23h 55m

Santa Cruz de la Sierra Viru Viru Intl

Mon 20/4

02:55-07:40

1 stop22h 45m

£790

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 20/3

07:05-02:35

2 stops24h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 20/4

02:55-11:10

1 stop26h 15m

£791

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 10/5

07:05-01:50

2 stops24h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 23/5

02:55-07:40

1 stop22h 45m

£792

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 13/4

09:40-01:50

1 stop22h 10m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/5

02:55-13:55

2 stops29h 00m

£794

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Thu 29/1

06:35-02:35

1 stop25h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sun 22/2

03:40-08:50

1 stop24h 10m

£808

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 10/2

07:05-02:35

2 stops24h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/3

03:40-13:25

1 stop28h 45m

£815

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 10/2

07:05-02:35

2 stops24h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/3

03:40-13:25

1 stop28h 45m

£816

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 13/4

13:10-01:50

1 stop18h 40m

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/5

02:55-13:55

2 stops29h 00m

£818

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from Madrid to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Cruz de la Sierra?

The month of May is, on average, the cheapest month to fly to Santa Cruz de la Sierra from Madrid, with most prices found around £648. If you aren’t able to travel during the month of May, then book flights to Santa Cruz de la Sierra from Madrid during March instead. Flights to Santa Cruz de la Sierra in March, while not as cheap as those in May, still average around £659.

What is the cheapest day to depart on your flight to Santa Cruz de la Sierra?

The cheapest day to depart on your flight to Santa Cruz de la Sierra is on a Wednesday when prices can be found for as low as £718. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Santa Cruz de la Sierra is Saturday, with ticket prices averaging around £1,561.

What is the cheapest time of day to depart on your flight to Santa Cruz de la Sierra?

The cheapest time of day to fly to Santa Cruz de la Sierra is in the afternoon when flights can be purchased for as low as £657. In contrast, the most expensive time of day to depart to Santa Cruz de la Sierra is in the morning when prices are around £960.

What is the cheapest Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flight route?

Fly from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl for the best Madrid Barajas - Santa Cruz de la Sierra Viru Viru Intl flight prices

How far in advance should I book a flight to Santa Cruz de la Sierra?

You are more likely to see cheaper flights to Santa Cruz de la Sierra from Madrid when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Cruz de la Sierra for around £805 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Cruz de la Sierra from Madrid for as low as £635 on momondo.

What cabin class options are available on Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flights?

There are 2 cabin classes available to choose from on Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Madrid to Santa Cruz de la Sierra flights?

No. A direct flight is the cheapest option for a flight between Madrid to Santa Cruz de la Sierra.

How have Madrid to Santa Cruz de la Sierra flight prices changed over time?

As of December 2025, prices for Madrid to Santa Cruz de la Sierra flights are approximately 30% more expensive when compared to flights at the same time last year.

When to book flights from Madrid to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Madrid to Santa Cruz de la Sierra (MAD to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Santa Cruz de la Sierra

Fastest flight time

11h 20m

Direct flights

Mon, Tue, Thu and Sat

Airports in Santa Cruz de la Sierra

1 airport
The fastest flight from Madrid to Santa Cruz de la Sierra takes 11h 20m
Direct flights go from Madrid to Santa Cruz de la Sierra on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights..
There is 1 airport in Santa Cruz de la Sierra. From Madrid there are direct flights to Santa Cruz de la Sierra Viru Viru Intl (VVI).
Search flight deals

  • How far is Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The straight-line distance from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl is 5537.8 mi. Typically, this will take 11h 20m by plane in normal conditions.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport were last updated today.

  • How many operators does momondo search for flights from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The travel and health documents required for your trip to Santa Cruz de la Sierra Viru Viru Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Cruz de la Sierra Viru Viru Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Madrid to Santa Cruz de la Sierra?

  • What is the most popular airline from Madrid to Santa Cruz de la Sierra?

Best airlines flying from Madrid to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Madrid to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom £565Free CancellationRating
6.6
2,490 reviews
Search Avianca flights

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Santa Cruz de la Sierra?

Finding the right flight to Santa Cruz de la Sierra from Madrid is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Cruz de la Sierra quick and easy, saving you time and money.

Can I find flights from Madrid to Santa Cruz de la Sierra with flexible booking policies on momondo?

All flight searches from Madrid to Santa Cruz de la Sierra on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Madrid to Santa Cruz de la Sierra?

Once all potential Madrid to Santa Cruz de la Sierra flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Madrid to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra from Madrid and alert you when they change.

An easier way to manage your Santa Cruz de la Sierra trip

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