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Cheap flights from Manchester to Knoxville from £395

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 11/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Manchester to Knoxville

Cheap return flights

Enter your travel dates to find the best prices.
Lufthansa Logo
10:35 - 10:08
MAN
-
TYS
28h 33m
2 stops
Lufthansa Logo
20:30 - 10:40
TYS
-
MAN
33h 10m
2 stops
£722Lufthansa
Sat, 25 Apr - Sun, 3 May
British Airways Logo
05:40 - 20:40
MAN
-
TYS
20h 00m
2 stops
British Airways Logo
16:15 - 11:45
TYS
-
MAN
14h 30m
2 stops
£726British Airways
Thu, 26 Feb - Mon, 2 Mar
Lufthansa Logo
10:35 - 22:29
MAN
-
TYS
16h 54m
2 stops
Lufthansa Logo
20:30 - 17:20
TYS
-
MAN
15h 50m
2 stops
£749Lufthansa
Sat, 25 Apr - Sun, 3 May
British Airways Logo
06:45 - 21:21
MAN
-
TYS
19h 36m
2 stops
British Airways Logo
07:00 - 09:55
TYS
-
MAN
21h 55m
2 stops
£758British Airways
Sat, 25 Apr - Sun, 3 May
British Airways Logo
16:45 - 20:18
MAN
-
TYS
32h 33m
2 stops
British Airways Logo
07:00 - 09:55
TYS
-
MAN
21h 55m
2 stops
£760British Airways
Sat, 25 Apr - Sun, 3 May
Delta Logo
13:15 - 23:54
MAN
-
TYS
15h 39m
1 stop
Delta Logo
10:06 - 07:15
TYS
-
MAN
16h 09m
1 stop
£774Delta
Sat, 25 Apr - Sun, 3 May
Delta Logo
13:15 - 21:40
MAN
-
TYS
13h 25m
1 stop
Delta Logo
09:05 - 07:15
TYS
-
MAN
17h 10m
1 stop
£775Delta
Sat, 25 Apr - Sun, 3 May
Delta Logo
05:50 - 23:54
MAN
-
TYS
23h 04m
2 stops
Delta Logo
10:05 - 07:15
TYS
-
MAN
16h 10m
1 stop
£780Delta
Sat, 25 Apr - Sun, 3 May
Delta Logo
13:15 - 10:21
MAN
-
TYS
26h 06m
2 stops
Delta Logo
09:05 - 07:15
TYS
-
MAN
17h 10m
1 stop
£788Delta
Sat, 25 Apr - Sun, 3 May
Delta Logo
13:15 - 10:21
MAN
-
TYS
26h 06m
2 stops
Delta Logo
05:44 - 07:15
TYS
-
MAN
20h 31m
1 stop
£789Delta
Sat, 25 Apr - Sun, 3 May

Delta flights from Manchester to Knoxville

Our best Delta deals on Manchester to Knoxville flight tickets
Delta
25 Apr
MAN13:15Manchester
15h 39m
1 stop
TYS23:54Knoxville McGhee Tyson
3 May
TYS10:06Knoxville McGhee Tyson
16h 09m
1 stop
MAN07:15Manchester
£774
Delta
25 Apr
MAN13:15Manchester
13h 25m
1 stop
TYS21:40Knoxville McGhee Tyson
3 May
TYS09:05Knoxville McGhee Tyson
17h 10m
1 stop
MAN07:15Manchester
£775
Delta
25 Apr
MAN05:50Manchester
23h 04m
2 stops
TYS23:54Knoxville McGhee Tyson
3 May
TYS10:05Knoxville McGhee Tyson
16h 10m
1 stop
MAN07:15Manchester
£780

Virgin Atlantic flights from Manchester to Knoxville

Our best Virgin Atlantic deals on Manchester to Knoxville flight tickets
Virgin Atlantic
30 Mar
MAN20:50Manchester
24h 16m
2 stops
TYS16:06Knoxville McGhee Tyson
6 Apr
TYS17:10Knoxville McGhee Tyson
10h 40m
1 stop
MAN08:50Manchester
£823
Virgin Atlantic
30 Mar
MAN20:50Manchester
24h 16m
2 stops
TYS16:06Knoxville McGhee Tyson
6 Apr
TYS11:18Knoxville McGhee Tyson
18h 02m
2 stops
MAN10:20Manchester
£824
Virgin Atlantic
18 Mar
MAN13:30Manchester
14h 27m
1 stop
TYS23:57Knoxville McGhee Tyson
20 Mar
TYS17:10Knoxville McGhee Tyson
13h 20m
1 stop
MAN10:30Manchester
£940

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 15 February 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

10:35-10:08

2 stops28h 33m

Knoxville McGhee Tyson

Sun 3/5

20:30-10:40

2 stops33h 10m

£722

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 26/2

05:40-20:40

2 stops20h 00m

Knoxville McGhee Tyson

Mon 2/3

16:15-11:45

2 stops14h 30m

£726

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

10:35-22:29

2 stops16h 54m

Knoxville McGhee Tyson

Sun 3/5

20:30-17:20

2 stops15h 50m

£749

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

06:45-21:21

2 stops19h 36m

Knoxville McGhee Tyson

Sun 3/5

07:00-09:55

2 stops21h 55m

£758

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

16:45-20:18

2 stops32h 33m

Knoxville McGhee Tyson

Sun 3/5

07:00-09:55

2 stops21h 55m

£760

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

13:15-23:54

1 stop15h 39m

Knoxville McGhee Tyson

Sun 3/5

10:06-07:15

1 stop16h 09m

£774

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

13:15-21:40

1 stop13h 25m

Knoxville McGhee Tyson

Sun 3/5

09:05-07:15

1 stop17h 10m

£775

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

05:50-23:54

2 stops23h 04m

Knoxville McGhee Tyson

Sun 3/5

10:05-07:15

1 stop16h 10m

£780

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

13:15-10:21

2 stops26h 06m

Knoxville McGhee Tyson

Sun 3/5

09:05-07:15

1 stop17h 10m

£788

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

13:15-10:21

2 stops26h 06m

Knoxville McGhee Tyson

Sun 3/5

05:44-07:15

1 stop20h 31m

£789

Flights are sorted by cheapest return flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of November is, on average, the cheapest month to fly to Knoxville from Manchester, with most prices found around £664. If you aren’t able to travel to Knoxville during the month of November, then flying in April is also cheap. Prices for this month can be found on momondo for an average of £669.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around £739 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester for as low as £603 on momondo.

Can stopping save me money on Manchester to Knoxville flights?

You could potentially save up to 12% on your flight if you consider stops on a Manchester to Knoxville flight.

When to book flights from Manchester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville

Fastest flight time

16h 22m

Direct flights

None
The fastest flight from Manchester to Knoxville takes 16h 22m
There are no direct flights from Manchester to Knoxville. There are no popular flight routes from Manchester to Knoxville.
Search flight deals

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 16h 22m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Knoxville?

Best airlines flying from Manchester to Knoxville

Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
FinnairPriceFrom £511Free CancellationRating
7.6
1,362 reviews
Search Finnair flights
United AirlinesPriceFrom £537Free CancellationRating
7.4
9,299 reviews
Search United Airlines flights
British AirwaysPriceFrom £560Free CancellationRating
6.7
7,750 reviews
Search British Airways flights
Virgin AtlanticPriceFrom £567Free CancellationRating
7.5
678 reviews
Search Virgin Atlantic flights
DeltaPriceFrom £695Free CancellationRating
7.9
8,204 reviews
Search Delta flights

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Newport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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