Cheap flights from Manchester to Knoxville from £601
This is the cheapest return flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 28/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Thu 28/1
10:10-23:46
2 stops18h 36m
Knoxville McGhee Tyson
Mon 1/2
17:57-18:35
2 stops19h 38m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Thu 28/1
10:10-23:46
2 stops18h 36m
Knoxville McGhee Tyson
Mon 1/2
17:57-18:35
2 stops19h 38m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Thu 28/1
10:10-23:46
2 stops18h 36m
Knoxville McGhee Tyson
Mon 1/2
17:57-18:35
2 stops19h 38m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Thu 11/2
10:10-21:45
2 stops16h 35m
Knoxville McGhee Tyson
Thu 18/2
17:57-18:35
2 stops19h 38m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Tue 3/11
09:40-20:49
2 stops16h 09m
Knoxville McGhee Tyson
Tue 10/11
16:59-14:05
2 stops16h 06m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Tue 3/11
12:40-22:02
1 stop14h 22m
Knoxville McGhee Tyson
Tue 10/11
18:10-10:30
1 stop11h 20m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Tue 3/11
20:40-19:49
2 stops28h 09m
Knoxville McGhee Tyson
Tue 10/11
18:10-10:30
1 stop11h 20m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Thu 11/2
14:55-18:13
1 stop32h 18m
Knoxville McGhee Tyson
Thu 18/2
17:57-10:50
1 stop11h 53m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Sun 22/11
19:55-16:36
2 stops25h 41m
Knoxville McGhee Tyson
Sun 29/11
20:04-20:10
2 stops19h 06m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Sun 22/11
09:05-22:22
2 stops18h 17m
Knoxville McGhee Tyson
Sun 29/11
09:02-06:40
1 stop16h 38m
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How to get the cheapest flight ticket from Manchester to Knoxville
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When to book flights from Manchester to Knoxville
Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville
Frequently asked questions about flying from Manchester to Knoxville
How far is Manchester to Knoxville McGhee Tyson by plane?
Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 16h 09m is a normal flight duration for this route.
When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.
How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?
There are 3 operators available for flights from Manchester Airport to Knoxville McGhee Tyson Airport as of October 2026.
How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Manchester to Knoxville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Manchester to Knoxville is Virgin Atlantic (84% of total bookings). The next most popular airlines are Delta (9%) and British Airways (8%).
Best airlines flying from Manchester to Knoxville
Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom £604 | Free Cancellation | Rating 6.7 8,255 reviews | |||
| PriceFrom £656 | Free Cancellation | Rating 7.5 694 reviews | |||
| PriceFrom £719 | Free Cancellation | Rating 7.8 8,646 reviews |
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We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.
Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?
momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.
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