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Cheap flights from Manchester to Knoxville from £335

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 22/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Manchester to Knoxville

Cheap return flights

Enter your travel dates to find the best prices.
Iberia Logo
06:15 - 22:09
MAN
-
TYS
20h 54m
2 stops
Iberia Logo
05:45 - 16:30
TYS
-
MAN
29h 45m
2 stops
£588Iberia
Tue, 10 Feb - Tue, 17 Feb
Virgin Atlantic Logo
13:30 - 23:45
MAN
-
TYS
15h 15m
1 stop
Virgin Atlantic Logo
14:38 - 10:30
TYS
-
MAN
14h 52m
1 stop
£603Virgin Atlantic
Tue, 10 Feb - Tue, 17 Feb
Virgin Atlantic Logo
13:00 - 23:45
MAN
-
TYS
15h 45m
2 stops
Virgin Atlantic Logo
12:00 - 10:30
TYS
-
MAN
17h 30m
1 stop
£620Virgin Atlantic
Tue, 10 Feb - Tue, 17 Feb
United Airlines Logo
06:05 - 20:52
MAN
-
TYS
19h 47m
2 stops
United Airlines Logo
11:07 - 17:00
TYS
-
MAN
24h 53m
2 stops
£623United Airlines
Fri, 30 Jan - Fri, 6 Feb
United Airlines Logo
06:05 - 20:52
MAN
-
TYS
19h 47m
2 stops
United Airlines Logo
06:45 - 12:20
TYS
-
MAN
24h 35m
2 stops
£624United Airlines
Fri, 30 Jan - Fri, 6 Feb
Iberia Logo
06:45 - 20:01
MAN
-
TYS
18h 16m
2 stops
Iberia Logo
11:43 - 09:55
TYS
-
MAN
17h 12m
2 stops
£663Iberia
Sat, 25 Apr - Sun, 3 May
Iberia Logo
06:45 - 21:35
MAN
-
TYS
19h 50m
2 stops
Iberia Logo
18:54 - 19:20
TYS
-
MAN
19h 26m
2 stops
£664Iberia
Sat, 25 Apr - Sun, 3 May
Iberia Logo
06:45 - 22:25
MAN
-
TYS
20h 40m
2 stops
Iberia Logo
16:09 - 16:05
TYS
-
MAN
18h 56m
2 stops
£665Iberia
Sat, 25 Apr - Sun, 3 May
Virgin Atlantic Logo
13:25 - 23:45
MAN
-
TYS
15h 20m
1 stop
Virgin Atlantic Logo
14:37 - 10:30
TYS
-
MAN
14h 53m
1 stop
£670Virgin Atlantic
Fri, 30 Jan - Fri, 6 Feb
Multiple Airlines Logo
07:00 - 19:42
MAN
-
TYS
17h 42m
2 stops
Multiple Airlines Logo
13:53 - 10:25
TYS
-
MAN
15h 32m
2 stops
£679Multiple Airlines
Sat, 11 Apr - Wed, 15 Apr

United Airlines flights from Manchester to Knoxville

Our best United Airlines deals on Manchester to Knoxville flight tickets
United Airlines
26 Feb
MAN06:00Manchester
19h 37m
2 stops
TYS20:37Knoxville McGhee Tyson
2 Mar
TYS09:40Knoxville McGhee Tyson
21h 40m
2 stops
MAN12:20Manchester
£621
United Airlines
30 Jan
MAN06:05Manchester
19h 47m
2 stops
TYS20:52Knoxville McGhee Tyson
6 Feb
TYS11:07Knoxville McGhee Tyson
24h 53m
2 stops
MAN17:00Manchester
£623
United Airlines
30 Jan
MAN06:05Manchester
19h 47m
2 stops
TYS20:52Knoxville McGhee Tyson
6 Feb
TYS09:30Knoxville McGhee Tyson
26h 30m
2 stops
MAN17:00Manchester
£624

Delta flights from Manchester to Knoxville

Our best Delta deals on Manchester to Knoxville flight tickets
Delta
30 Jan
MAN13:00Manchester
28h 13m
2 stops
TYS12:13Knoxville McGhee Tyson
6 Feb
TYS08:25Knoxville McGhee Tyson
21h 05m
1 stop
MAN10:30Manchester
£691
Delta
30 Jan
MAN13:25Manchester
26h 43m
1 stop
TYS11:08Knoxville McGhee Tyson
6 Feb
TYS11:58Knoxville McGhee Tyson
17h 32m
1 stop
MAN10:30Manchester
£692
Delta
25 Apr
MAN13:15Manchester
27h 00m
1 stop
TYS11:15Knoxville McGhee Tyson
3 May
TYS05:30Knoxville McGhee Tyson
20h 45m
1 stop
MAN07:15Manchester
£703

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 16 January 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 10/2

06:15-22:09

2 stops20h 54m

Knoxville McGhee Tyson

Tue 17/2

05:45-16:30

2 stops29h 45m

£588

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 10/2

13:30-23:45

1 stop15h 15m

Knoxville McGhee Tyson

Tue 17/2

14:38-10:30

1 stop14h 52m

£603

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 10/2

13:00-23:45

2 stops15h 45m

Knoxville McGhee Tyson

Tue 17/2

12:00-10:30

1 stop17h 30m

£620

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 30/1

06:05-20:52

2 stops19h 47m

Knoxville McGhee Tyson

Fri 6/2

11:07-17:00

2 stops24h 53m

£623

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 30/1

06:05-20:52

2 stops19h 47m

Knoxville McGhee Tyson

Fri 6/2

06:45-12:20

2 stops24h 35m

£624

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

06:45-20:01

2 stops18h 16m

Knoxville McGhee Tyson

Sun 3/5

11:43-09:55

2 stops17h 12m

£663

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

06:45-21:35

2 stops19h 50m

Knoxville McGhee Tyson

Sun 3/5

18:54-19:20

2 stops19h 26m

£664

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

06:45-22:25

2 stops20h 40m

Knoxville McGhee Tyson

Sun 3/5

16:09-16:05

2 stops18h 56m

£665

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 30/1

13:25-23:45

1 stop15h 20m

Knoxville McGhee Tyson

Fri 6/2

14:37-10:30

1 stop14h 53m

£670

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 11/4

07:00-19:42

2 stops17h 42m

Knoxville McGhee Tyson

Wed 15/4

13:53-10:25

2 stops15h 32m

£679

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of March is, on average, the cheapest month to fly to Knoxville from Manchester, with most prices found around £651. If you aren’t able to travel to Knoxville during the month of March, then flying in January is also cheap. Prices for this month can be found on momondo for an average of £661.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around £750 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester for as low as £614 on momondo.

Can stopping save me money on Manchester to Knoxville flights?

You could potentially save up to 1% on your flight if you consider stops on a Manchester to Knoxville flight.

When to book flights from Manchester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville

Fastest flight time

19h 37m

Direct flights

None
The fastest flight from Manchester to Knoxville takes 19h 37m
There are no direct flights from Manchester to Knoxville. There are no popular flight routes from Manchester to Knoxville.
Search flight deals

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 19h 37m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Knoxville?

Best airlines flying from Manchester to Knoxville

Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom £547Free CancellationRating
7.4
9,164 reviews
Search United Airlines flights
FinnairPriceFrom £552Free CancellationRating
7.6
1,349 reviews
Search Finnair flights
British AirwaysPriceFrom £571Free CancellationRating
6.7
7,676 reviews
Search British Airways flights
Virgin AtlanticPriceFrom £578Free CancellationRating
7.5
678 reviews
Search Virgin Atlantic flights
KLMPriceFrom £591Free CancellationRating
7.7
1,440 reviews
Search KLM flights

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Newport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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