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Cheap flights from Manchester to Knoxville from £359

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 1/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Manchester to Knoxville

Cheap return flights

Enter your travel dates to find the best prices.
British Airways Logo
20:15 - 10:43
MAN
-
TYS
43h 28m
2 stops
British Airways Logo
06:21 - 09:50
TYS
-
MAN
22h 29m
2 stops
£766British Airways
Mon, 7 Sep - Tue, 22 Sep
Multiple Airlines Logo
13:00 - 21:46
MAN
-
TYS
13h 46m
1 stop
Multiple Airlines Logo
06:21 - 09:50
TYS
-
MAN
22h 29m
2 stops
£788Multiple Airlines
Mon, 7 Sep - Tue, 22 Sep
Multiple Airlines Logo
07:55 - 23:53
MAN
-
TYS
20h 58m
2 stops
Multiple Airlines Logo
13:38 - 15:10
TYS
-
MAN
20h 32m
2 stops
£796Multiple Airlines
Tue, 23 Jun - Tue, 30 Jun
Delta Logo
13:00 - 12:28
MAN
-
TYS
28h 28m
1 stop
Delta Logo
05:30 - 08:50
TYS
-
MAN
22h 20m
1 stop
£809Delta
Mon, 7 Sep - Tue, 22 Sep
Virgin Atlantic Logo
13:00 - 23:54
MAN
-
TYS
15h 54m
1 stop
Virgin Atlantic Logo
11:27 - 10:10
TYS
-
MAN
17h 43m
2 stops
£812Virgin Atlantic
Tue, 23 Jun - Tue, 30 Jun
Virgin Atlantic Logo
10:40 - 23:54
MAN
-
TYS
18h 14m
1 stop
Virgin Atlantic Logo
07:35 - 07:15
TYS
-
MAN
18h 40m
1 stop
£827Virgin Atlantic
Wed, 10 Jun - Wed, 17 Jun
Virgin Atlantic Logo
10:40 - 23:54
MAN
-
TYS
18h 14m
1 stop
Virgin Atlantic Logo
15:54 - 09:40
TYS
-
MAN
12h 46m
2 stops
£834Virgin Atlantic
Wed, 10 Jun - Wed, 17 Jun
Multiple Airlines Logo
08:50 - 18:13
MAN
-
TYS
14h 23m
2 stops
Multiple Airlines Logo
18:30 - 13:10
TYS
-
MAN
13h 40m
2 stops
£836Multiple Airlines
Thu, 18 Jun - Mon, 13 Jul
Virgin Atlantic Logo
11:00 - 21:41
MAN
-
TYS
15h 41m
2 stops
Virgin Atlantic Logo
13:59 - 09:40
TYS
-
MAN
14h 41m
2 stops
£840Virgin Atlantic
Wed, 10 Jun - Wed, 17 Jun
Virgin Atlantic Logo
13:00 - 20:14
MAN
-
TYS
12h 14m
1 stop
Virgin Atlantic Logo
15:54 - 08:50
TYS
-
MAN
11h 56m
1 stop
£842Virgin Atlantic
Thu, 18 Jun - Mon, 13 Jul

Virgin Atlantic flights from Manchester to Knoxville

Our best Virgin Atlantic deals on Manchester to Knoxville flight tickets
Virgin Atlantic
23 Jun
MAN13:00Manchester
15h 54m
1 stop
TYS23:54Knoxville McGhee Tyson
30 Jun
TYS11:27Knoxville McGhee Tyson
17h 43m
2 stops
MAN10:10Manchester
£812
Virgin Atlantic
10 Jun
MAN10:40Manchester
18h 14m
1 stop
TYS23:54Knoxville McGhee Tyson
17 Jun
TYS07:35Knoxville McGhee Tyson
18h 40m
1 stop
MAN07:15Manchester
£827
Virgin Atlantic
10 Jun
MAN10:40Manchester
18h 14m
1 stop
TYS23:54Knoxville McGhee Tyson
17 Jun
TYS15:54Knoxville McGhee Tyson
12h 46m
2 stops
MAN09:40Manchester
£834

United Airlines flights from Manchester to Knoxville

Our best United Airlines deals on Manchester to Knoxville flight tickets
United Airlines
1 Jun
MAN10:35Manchester
29h 07m
2 stops
TYS10:42Knoxville McGhee Tyson
17 Jun
TYS05:45Knoxville McGhee Tyson
23h 40m
2 stops
MAN10:25Manchester
£989
United Airlines
1 Jun
MAN10:35Manchester
39h 21m
3 stops
TYS20:56Knoxville McGhee Tyson
20 Jun
TYS05:45Knoxville McGhee Tyson
19h 45m
2 stops
MAN06:30Manchester
£1,021
United Airlines
9 Nov
MAN11:50Manchester
14h 15m
2 stops
TYS21:05Knoxville McGhee Tyson
12 Nov
TYS14:20Knoxville McGhee Tyson
21h 35m
2 stops
MAN16:55Manchester
£1,654

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 13 May 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 7/9

20:15-10:43

2 stops43h 28m

Knoxville McGhee Tyson

Tue 22/9

06:21-09:50

2 stops22h 29m

£766

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 7/9

13:00-21:46

1 stop13h 46m

Knoxville McGhee Tyson

Tue 22/9

06:21-09:50

2 stops22h 29m

£788

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 23/6

07:55-23:53

2 stops20h 58m

Knoxville McGhee Tyson

Tue 30/6

13:38-15:10

2 stops20h 32m

£796

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 7/9

13:00-12:28

1 stop28h 28m

Knoxville McGhee Tyson

Tue 22/9

05:30-08:50

1 stop22h 20m

£809

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 23/6

13:00-23:54

1 stop15h 54m

Knoxville McGhee Tyson

Tue 30/6

11:27-10:10

2 stops17h 43m

£812

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 10/6

10:40-23:54

1 stop18h 14m

Knoxville McGhee Tyson

Wed 17/6

07:35-07:15

1 stop18h 40m

£827

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 10/6

10:40-23:54

1 stop18h 14m

Knoxville McGhee Tyson

Wed 17/6

15:54-09:40

2 stops12h 46m

£834

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 18/6

08:50-18:13

2 stops14h 23m

Knoxville McGhee Tyson

Mon 13/7

18:30-13:10

2 stops13h 40m

£836

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 10/6

11:00-21:41

2 stops15h 41m

Knoxville McGhee Tyson

Wed 17/6

13:59-09:40

2 stops14h 41m

£840
Fastest return journey

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 18/6

13:00-20:14

1 stop12h 14m

Knoxville McGhee Tyson

Mon 13/7

15:54-08:50

1 stop11h 56m

£842

Flights are sorted by cheapest return flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of May is, on average, the cheapest month to fly to Knoxville from Manchester, with most prices found around £649. If you aren’t able to travel to Knoxville during the month of May, then flying in March is also cheap. Prices for this month can be found on momondo for an average of £655.

Can stopping save me money on Manchester to Knoxville flights?

You could potentially save up to 27% on your flight if you consider stops on a Manchester to Knoxville flight.

When to book flights from Manchester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville

Fastest flight time

15h 50m

Direct flights

None
The fastest flight from Manchester to Knoxville takes 15h 50m
There are no direct flights from Manchester to Knoxville. There are no popular flight routes from Manchester to Knoxville.
Search flight deals

Frequently asked questions about flying from Manchester to Knoxville

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 15h 50m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Knoxville?

Best airlines flying from Manchester to Knoxville

Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom £542Free CancellationRating
7.4
9,704 reviews
Search United Airlines flights
British AirwaysPriceFrom £564Free CancellationRating
6.7
7,975 reviews
Search British Airways flights
FinnairPriceFrom £575Free CancellationRating
7.6
1,393 reviews
Search Finnair flights
Virgin AtlanticPriceFrom £603Free CancellationRating
7.4
688 reviews
Search Virgin Atlantic flights
DeltaPriceFrom £701Free CancellationRating
7.9
8,450 reviews
Search Delta flights

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Newport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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