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Cheap flights from Manchester to Knoxville from £375

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 15/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Manchester to Knoxville

Cheap return flights

Enter your travel dates to find the best prices.
Lufthansa Logo
06:45 - 19:27MAN-TYS
17h 42m2 stops
Lufthansa Logo
14:25 - 10:30TYS-MAN
15h 05m2 stops
£619Lufthansa
Find Deal
Sat, 17 Jan - Sat, 24 Jan
Lufthansa Logo
06:25 - 19:27MAN-TYS
18h 02m2 stops
Lufthansa Logo
14:25 - 10:30TYS-MAN
15h 05m2 stops
£629Lufthansa
Find Deal
Fri, 16 Jan - Fri, 23 Jan
United Airlines Logo
06:00 - 20:52MAN-TYS
19h 52m2 stops
United Airlines Logo
09:05 - 17:00TYS-MAN
26h 55m2 stops
£642United Airlines
Find Deal
Thu, 22 Jan - Mon, 26 Jan
United Airlines Logo
06:00 - 19:27MAN-TYS
18h 27m2 stops
United Airlines Logo
11:07 - 17:00TYS-MAN
24h 53m2 stops
£643United Airlines
Find Deal
Thu, 22 Jan - Mon, 26 Jan
British Airways Logo
07:50 - 23:06MAN-TYS
20h 16m2 stops
British Airways Logo
18:22 - 13:15TYS-MAN
37h 53m2 stops
£691British Airways
Find Deal
Sat, 25 Apr - Sun, 3 May
Lufthansa Logo
11:10 - 17:28MAN-TYS
59h 18m2 stops
Lufthansa Logo
14:00 - 10:25TYS-MAN
39h 25m2 stops
£711Lufthansa
Find Deal
Sat, 25 Apr - Sun, 3 May
United Airlines Logo
06:05 - 19:27MAN-TYS
18h 22m3 stops
United Airlines Logo
13:59 - 12:10TYS-MAN
17h 11m2 stops
£716United Airlines
Find Deal
Sat, 17 Jan - Sat, 24 Jan
Delta Logo
13:30 - 21:24MAN-TYS
12h 54m1 stop
Delta Logo
11:58 - 10:10TYS-MAN
17h 12m2 stops
£728Delta
Find Deal
Thu, 22 Jan - Mon, 26 Jan
Virgin Atlantic Logo
13:30 - 23:45MAN-TYS
15h 15m1 stop
Virgin Atlantic Logo
14:37 - 10:30TYS-MAN
14h 53m1 stop
£734Virgin Atlantic
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Sat, 17 Jan - Sat, 24 Jan
Virgin Atlantic Logo
13:25 - 18:52MAN-TYS
34h 27m1 stop
Virgin Atlantic Logo
14:37 - 10:30TYS-MAN
14h 53m1 stop
£737Virgin Atlantic
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Fri, 16 Jan - Fri, 23 Jan

Air France flights from Manchester to Knoxville

Our best Air France deals on Manchester to Knoxville flight tickets
Air France
4 Feb
MAN13:30Manchester
15h 15m
1 stop
TYS23:45Knoxville McGhee Tyson
8 Feb
TYS14:37Knoxville McGhee Tyson
14h 33m
2 stops
MAN10:10Manchester
£770
Find similar
Air France
30 Dec
MAN13:30Manchester
12h 45m
1 stop
TYS21:15Knoxville McGhee Tyson
6 Jan
TYS13:00Knoxville McGhee Tyson
22h 05m
2 stops
MAN16:05Manchester
£923
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Lufthansa flights from Manchester to Knoxville

Our best Lufthansa deals on Manchester to Knoxville flight tickets
Lufthansa
17 Jan
MAN06:45Manchester
17h 42m
2 stops
TYS19:27Knoxville McGhee Tyson
24 Jan
TYS14:25Knoxville McGhee Tyson
15h 05m
2 stops
MAN10:30Manchester
£618
Find similar
Lufthansa
16 Jan
MAN06:25Manchester
18h 02m
2 stops
TYS19:27Knoxville McGhee Tyson
23 Jan
TYS14:25Knoxville McGhee Tyson
15h 05m
2 stops
MAN10:30Manchester
£629
Find similar
Lufthansa
4 Feb
MAN06:00Manchester
18h 27m
2 stops
TYS19:27Knoxville McGhee Tyson
8 Feb
TYS13:59Knoxville McGhee Tyson
17h 21m
2 stops
MAN12:20Manchester
£644
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 4 December 2025.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 17/1

06:45-19:27

2 stops17h 42m

Knoxville McGhee Tyson

Sat 24/1

14:25-10:30

2 stops15h 05m

£618

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 16/1

06:25-19:27

2 stops18h 02m

Knoxville McGhee Tyson

Fri 23/1

14:25-10:30

2 stops15h 05m

£629

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 22/1

06:00-20:52

2 stops19h 52m

Knoxville McGhee Tyson

Mon 26/1

09:05-17:00

2 stops26h 55m

£642

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 22/1

06:00-19:27

2 stops18h 27m

Knoxville McGhee Tyson

Mon 26/1

11:07-17:00

2 stops24h 53m

£643

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

07:50-23:06

2 stops20h 16m

Knoxville McGhee Tyson

Sun 3/5

18:22-13:15

2 stops37h 53m

£691

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

11:10-17:28

2 stops59h 18m

Knoxville McGhee Tyson

Sun 3/5

14:00-10:25

2 stops39h 25m

£711

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 17/1

06:05-19:27

3 stops18h 22m

Knoxville McGhee Tyson

Sat 24/1

13:59-12:10

2 stops17h 11m

£716

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 22/1

13:30-21:24

1 stop12h 54m

Knoxville McGhee Tyson

Mon 26/1

11:58-10:10

2 stops17h 12m

£728

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 17/1

13:30-23:45

1 stop15h 15m

Knoxville McGhee Tyson

Sat 24/1

14:37-10:30

1 stop14h 53m

£734

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 16/1

13:25-18:52

1 stop34h 27m

Knoxville McGhee Tyson

Fri 23/1

14:37-10:30

1 stop14h 53m

£737

Flights are sorted by cheapest return flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of April is, on average, the cheapest month to fly to Knoxville from Manchester, with most prices found around £671. If you aren’t able to travel to Knoxville during the month of April, then flying in March is also cheap. Prices for this month can be found on momondo for an average of £679.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart on your flight to Knoxville is on a Friday when prices can be found for as low as £715. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around £827. These prices are subject to change though, so be sure to set up a Price Alert for flights to Knoxville.

What is the cheapest time of day to depart on your flight to Knoxville?

Flying to Knoxville from Manchester in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as £545 when looking at flights departing in the afternoon. If you have a flexible travel schedule, then try to avoid flying at midday when prices are £753 on average. Flights to Knoxville from Manchester at midday are generally more expensive because this time of day is more convenient for travellers’ schedules.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around £763 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester for as low as £551 on momondo.

Can stopping save me money on Manchester to Knoxville flights?

You could potentially save up to 13% on your flight if you consider stops on a Manchester to Knoxville flight.

When to book flights from Manchester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville

Fastest flight time

17h 42m

Direct flights

None
The fastest flight from Manchester to Knoxville takes 17h 42m
There are no direct flights from Manchester to Knoxville. There are no popular flight routes from Manchester to Knoxville.
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  • How far is Manchester to Knoxville McGhee Tyson by plane?

    Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 12h 45m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Knoxville?

Best airlines flying from Manchester to Knoxville

Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom £552Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights
FinnairPriceFrom £557Free CancellationRating
7.6
1,334 reviews
Search Finnair flights
British AirwaysPriceFrom £576Free CancellationRating
6.7
7,557 reviews
Search British Airways flights
Virgin AtlanticPriceFrom £583Free CancellationRating
7.5
675 reviews
Search Virgin Atlantic flights
KLMPriceFrom £597Free CancellationRating
7.7
1,428 reviews
Search KLM flights

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Newport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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