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Cheap flights from Manchester to Knoxville from £514

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 22/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Manchester to Knoxville

Cheap return flights

Enter your travel dates to find the best prices.
Lufthansa Logo
10:35 - 23:59
MAN
-
TYS
18h 24m
2 stops
Lufthansa Logo
19:20 - 17:20
TYS
-
MAN
41h 00m
2 stops
£740Lufthansa
Mon, 14 Sep - Wed, 23 Sep
Lufthansa Logo
10:35 - 22:49
MAN
-
TYS
17h 14m
2 stops
Lufthansa Logo
19:20 - 17:20
TYS
-
MAN
41h 00m
2 stops
£741Lufthansa
Mon, 14 Sep - Wed, 23 Sep
Lufthansa Logo
10:35 - 23:59
MAN
-
TYS
18h 24m
2 stops
Lufthansa Logo
18:00 - 17:20
TYS
-
MAN
42h 20m
2 stops
£744Lufthansa
Mon, 14 Sep - Wed, 23 Sep
Lufthansa Logo
10:35 - 22:49
MAN
-
TYS
17h 14m
2 stops
Lufthansa Logo
19:20 - 17:20
TYS
-
MAN
41h 00m
2 stops
£745Lufthansa
Mon, 14 Sep - Wed, 23 Sep
Virgin Atlantic Logo
20:50 - 17:38
MAN
-
TYS
25h 48m
2 stops
Virgin Atlantic Logo
12:00 - 07:15
TYS
-
MAN
14h 15m
1 stop
£757Virgin Atlantic
Mon, 14 Sep - Wed, 23 Sep
United Airlines Logo
09:30 - 23:37
MAN
-
TYS
19h 07m
2 stops
United Airlines Logo
19:35 - 17:00
TYS
-
MAN
16h 25m
2 stops
£761United Airlines
Fri, 20 Nov - Mon, 30 Nov
Virgin Atlantic Logo
13:00 - 20:07
MAN
-
TYS
12h 07m
1 stop
Virgin Atlantic Logo
07:40 - 08:25
TYS
-
MAN
19h 45m
2 stops
£762Virgin Atlantic
Mon, 14 Sep - Wed, 23 Sep
United Airlines Logo
06:10 - 19:17
MAN
-
TYS
18h 07m
2 stops
United Airlines Logo
10:16 - 10:20
TYS
-
MAN
19h 04m
2 stops
£763United Airlines
Tue, 24 Nov - Mon, 30 Nov
Virgin Atlantic Logo
13:00 - 23:50
MAN
-
TYS
15h 50m
1 stop
Virgin Atlantic Logo
11:45 - 10:10
TYS
-
MAN
17h 25m
2 stops
£764Virgin Atlantic
Mon, 14 Sep - Wed, 23 Sep
Virgin Atlantic Logo
13:00 - 20:07
MAN
-
TYS
12h 07m
1 stop
Virgin Atlantic Logo
12:00 - 07:15
TYS
-
MAN
14h 15m
1 stop
£766Virgin Atlantic
Mon, 14 Sep - Wed, 23 Sep

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Virgin Atlantic flights from Manchester to Knoxville

Our best Virgin Atlantic deals on Manchester to Knoxville flight tickets
Virgin Atlantic
14 Sept
MAN20:50Manchester
25h 48m
2 stops
TYS17:38Knoxville McGhee Tyson
23 Sept
TYS12:00Knoxville McGhee Tyson
14h 15m
1 stop
MAN07:15Manchester
£757
Virgin Atlantic
14 Sept
MAN13:00Manchester
12h 07m
1 stop
TYS20:07Knoxville McGhee Tyson
23 Sept
TYS07:40Knoxville McGhee Tyson
19h 45m
2 stops
MAN08:25Manchester
£762
Virgin Atlantic
14 Sept
MAN13:00Manchester
15h 50m
1 stop
TYS23:50Knoxville McGhee Tyson
23 Sept
TYS11:45Knoxville McGhee Tyson
17h 25m
2 stops
MAN10:10Manchester
£764

Lufthansa flights from Manchester to Knoxville

Our best Lufthansa deals on Manchester to Knoxville flight tickets
Lufthansa
14 Sept
MAN10:35Manchester
18h 24m
2 stops
TYS23:59Knoxville McGhee Tyson
23 Sept
TYS19:20Knoxville McGhee Tyson
41h 00m
2 stops
MAN17:20Manchester
£740
Lufthansa
14 Sept
MAN10:35Manchester
17h 14m
2 stops
TYS22:49Knoxville McGhee Tyson
23 Sept
TYS19:20Knoxville McGhee Tyson
41h 00m
2 stops
MAN17:20Manchester
£741
Lufthansa
14 Sept
MAN10:35Manchester
18h 24m
2 stops
TYS23:59Knoxville McGhee Tyson
23 Sept
TYS18:00Knoxville McGhee Tyson
42h 20m
2 stops
MAN17:20Manchester
£744

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 9 June 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

10:35-23:59

2 stops18h 24m

Knoxville McGhee Tyson

Wed 23/9

19:20-17:20

2 stops41h 00m

£740

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

10:35-22:49

2 stops17h 14m

Knoxville McGhee Tyson

Wed 23/9

19:20-17:20

2 stops41h 00m

£741

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

10:35-23:59

2 stops18h 24m

Knoxville McGhee Tyson

Wed 23/9

18:00-17:20

2 stops42h 20m

£744

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

10:35-22:49

2 stops17h 14m

Knoxville McGhee Tyson

Wed 23/9

19:20-17:20

2 stops41h 00m

£745

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

20:50-17:38

2 stops25h 48m

Knoxville McGhee Tyson

Wed 23/9

12:00-07:15

1 stop14h 15m

£757

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 20/11

09:30-23:37

2 stops19h 07m

Knoxville McGhee Tyson

Mon 30/11

19:35-17:00

2 stops16h 25m

£761

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

13:00-20:07

1 stop12h 07m

Knoxville McGhee Tyson

Wed 23/9

07:40-08:25

2 stops19h 45m

£762

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 24/11

06:10-19:17

2 stops18h 07m

Knoxville McGhee Tyson

Mon 30/11

10:16-10:20

2 stops19h 04m

£763

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

13:00-23:50

1 stop15h 50m

Knoxville McGhee Tyson

Wed 23/9

11:45-10:10

2 stops17h 25m

£764
Fastest return journey

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 14/9

13:00-20:07

1 stop12h 07m

Knoxville McGhee Tyson

Wed 23/9

12:00-07:15

1 stop14h 15m

£766

Flights are sorted by cheapest return flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of March is, on average, the cheapest month to fly to Knoxville from Manchester, with most prices found around £583. If you aren’t able to travel to Knoxville during the month of March, then flying in May is also cheap. Prices for this month can be found on momondo for an average of £644.

Can stopping save me money on Manchester to Knoxville flights?

You could potentially save up to 27% on your flight if you consider stops on a Manchester to Knoxville flight.

When to book flights from Manchester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville

Fastest flight time

15h 54m

Direct flights

None
The fastest flight from Manchester to Knoxville takes 15h 54m
There are no direct flights from Manchester to Knoxville. There are no popular flight routes from Manchester to Knoxville.
Search flight deals

Frequently asked questions about flying from Manchester to Knoxville

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 15h 54m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Knoxville?

Best airlines flying from Manchester to Knoxville

Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
British AirwaysPriceFrom £574Free CancellationRating
6.7
8,035 reviews
Search British Airways flights
Virgin AtlanticPriceFrom £611Free CancellationRating
7.5
689 reviews
Search Virgin Atlantic flights
DeltaPriceFrom £710Free CancellationRating
7.9
8,393 reviews
Search Delta flights

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Newport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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