Cheap flights from Manchester to Knoxville from £571

This is the cheapest return flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 23/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Voted winner of Europe's Best Travel App 2023

Save money when you book flights with momondo

Big names, great deals

Big names, great deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customise your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Manchester to Knoxville

Cheap return flights

Delta Logo
12:35 - 23:44MAN-TYS
16h 09m1 stop
Delta Logo
18:08 - 16:55TYS-MAN
17h 47m2 stops
£571Delta
Find Deal
Tue, 23 Sep - Tue, 30 Sep
Delta Logo
13:45 - 23:44MAN-TYS
14h 59m2 stops
Delta Logo
18:08 - 16:55TYS-MAN
17h 47m2 stops
£573Delta
Find Deal
Tue, 23 Sep - Tue, 30 Sep
Delta Logo
12:35 - 23:44MAN-TYS
16h 09m1 stop
Delta Logo
08:35 - 08:35TYS-MAN
19h 00m1 stop
£575Delta
Find Deal
Tue, 23 Sep - Tue, 30 Sep
Air Canada Logo
06:05 - 20:56MAN-TYS
19h 51m3 stops
Air Canada Logo
19:26 - 10:25TYS-MAN
33h 59m3 stops
£628Air Canada
Find Deal
Tue, 23 Sep - Tue, 30 Sep
British Airways Logo
09:20 - 20:44MAN-TYS
16h 24m2 stops
British Airways Logo
20:04 - 19:05TYS-MAN
18h 01m2 stops
£653British Airways
Find Deal
Wed, 22 Oct - Sat, 29 Nov
British Airways Logo
07:00 - 17:32MAN-TYS
15h 32m2 stops
British Airways Logo
18:11 - 22:40TYS-MAN
23h 29m2 stops
£738British Airways
Find Deal
Sat, 11 Oct - Sat, 18 Oct
 Logo
16:00 - 21:03MAN-TYS
34h 03m3 stops
 Logo
08:15 - 21:20TYS-MAN
32h 05m3 stops
£1,127
Find Deal
Sat, 11 Oct - Sat, 18 Oct
 Logo
18:00 - 21:03MAN-TYS
32h 03m3 stops
 Logo
08:15 - 10:05TYS-MAN
20h 50m2 stops
£1,172
Find Deal
Sat, 11 Oct - Sat, 18 Oct
Air Canada Logo
06:05 - 10:29MAN-TYS
33h 24m3 stops
Air Canada Logo
19:20 - 10:20TYS-MAN
34h 00m3 stops
£1,205Air Canada
Find Deal
Wed, 22 Oct - Sat, 29 Nov
Virgin Atlantic Logo
12:35 - 23:07MAN-TYS
15h 32m1 stop
Virgin Atlantic Logo
15:43 - 08:35TYS-MAN
11h 52m1 stop
£1,545Virgin Atlantic
Find Deal
Sat, 11 Oct - Sat, 18 Oct

Delta flights from Manchester to Knoxville

Our best Delta deals on Manchester to Knoxville flight tickets
Delta
23 Sept
MAN12:35Manchester
16h 09m
1 stop
TYS23:44Knoxville McGhee Tyson
30 Sept
TYS18:08Knoxville McGhee Tyson
17h 47m
2 stops
MAN16:55Manchester
Delta
23 Sept
MAN13:45Manchester
14h 59m
2 stops
TYS23:44Knoxville McGhee Tyson
30 Sept
TYS18:08Knoxville McGhee Tyson
17h 47m
2 stops
MAN16:55Manchester
Delta
23 Sept
MAN12:35Manchester
16h 09m
1 stop
TYS23:44Knoxville McGhee Tyson
30 Sept
TYS08:35Knoxville McGhee Tyson
19h 00m
1 stop
MAN08:35Manchester

Air Canada flights from Manchester to Knoxville

Our best Air Canada deals on Manchester to Knoxville flight tickets
Air Canada
23 Sept
MAN06:05Manchester
19h 51m
3 stops
TYS20:56Knoxville McGhee Tyson
30 Sept
TYS19:26Knoxville McGhee Tyson
33h 59m
3 stops
MAN10:25Manchester
Air Canada
22 Oct
MAN06:05Manchester
33h 24m
3 stops
TYS10:29Knoxville McGhee Tyson
29 Nov
TYS19:20Knoxville McGhee Tyson
34h 00m
3 stops
MAN10:20Manchester

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 29 August 2025.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 23/9

12:35-23:44

1 stop16h 09m

Knoxville McGhee Tyson

Tue 30/9

18:08-16:55

2 stops17h 47m

£571

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 23/9

13:45-23:44

2 stops14h 59m

Knoxville McGhee Tyson

Tue 30/9

18:08-16:55

2 stops17h 47m

£573

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 23/9

12:35-23:44

1 stop16h 09m

Knoxville McGhee Tyson

Tue 30/9

08:35-08:35

1 stop19h 00m

£575

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 23/9

06:05-20:56

3 stops19h 51m

Knoxville McGhee Tyson

Tue 30/9

19:26-10:25

3 stops33h 59m

£628

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 22/10

09:20-20:44

2 stops16h 24m

Knoxville McGhee Tyson

Sat 29/11

20:04-19:05

2 stops18h 01m

£653

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 11/10

07:00-17:32

2 stops15h 32m

Knoxville McGhee Tyson

Sat 18/10

18:11-22:40

2 stops23h 29m

£738

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 11/10

16:00-21:03

3 stops34h 03m

Knoxville McGhee Tyson

Sat 18/10

08:15-21:20

3 stops32h 05m

£1,127

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 11/10

18:00-21:03

3 stops32h 03m

Knoxville McGhee Tyson

Sat 18/10

08:15-10:05

2 stops20h 50m

£1,172

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 22/10

06:05-10:29

3 stops33h 24m

Knoxville McGhee Tyson

Sat 29/11

19:20-10:20

3 stops34h 00m

£1,205

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 11/10

12:35-23:07

1 stop15h 32m

Knoxville McGhee Tyson

Sat 18/10

15:43-08:35

1 stop11h 52m

£1,545

Flights are sorted by cheapest return flights first.

Sorted by cheapest first

See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Manchester, with most prices found around £669. If you aren’t able to travel to Knoxville during the month of February, then flying in November is also cheap. Prices for this month can be found on momondo for an average of £669.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart on your flight to Knoxville is on a Friday when prices can be found for as low as £703. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around £813. These prices are subject to change though, so be sure to set up a Price Alert for flights to Knoxville.

What is the cheapest time of day to depart on your flight to Knoxville?

Flying to Knoxville from Manchester in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as £536 when looking at flights departing in the afternoon. If you have a flexible travel schedule, then try to avoid flying at midday when prices are £741 on average. Flights to Knoxville from Manchester at midday are generally more expensive because this time of day is more convenient for travellers’ schedules.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around £762 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester for as low as £596 on momondo.

Can stopping save me money on Manchester to Knoxville flights?

You could potentially save up to 7% on your flight if you consider stops on a Manchester to Knoxville flight.

When to book flights from Manchester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville

Direct flights

None
There are no direct flights from Manchester to Knoxville. There are no popular flight routes from Manchester to Knoxville.
  • How far is Manchester to Knoxville McGhee Tyson by plane?

    Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 14h 59m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Knoxville?

Best airlines flying from Manchester to Knoxville

Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom £543Free CancellationRating
7.4
8,941 reviews
Search United Airlines flights
FinnairPriceFrom £553Free CancellationRating
7.6
1,321 reviews
Search Finnair flights
British AirwaysPriceFrom £569Free CancellationRating
6.7
7,316 reviews
Search British Airways flights
Air FrancePriceFrom £577Free CancellationRating
7.4
1,472 reviews
Search Air France flights
Virgin AtlanticPriceFrom £588Free CancellationRating
7.4
661 reviews
Search Virgin Atlantic flights
KLMPriceFrom £626Free CancellationRating
7.8
1,383 reviews
Search KLM flights

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Newport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organise and travel with friends or family. Trips is free – and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 3/9
Wed 10/9

Find better results for your trip to the United States