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Cheap flights from Manchester to Knoxville from £374

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 2/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap return flights

Enter your travel dates to find the best prices.
Virgin Atlantic Logo
13:30 - 23:52
MAN
-
TYS
15h 22m
1 stop
Virgin Atlantic Logo
15:13 - 10:30
TYS
-
MAN
15h 17m
1 stop
£597Virgin Atlantic
Wed, 4 Mar - Wed, 18 Mar
United Airlines Logo
13:00 - 10:49
MAN
-
TYS
26h 49m
2 stops
United Airlines Logo
06:45 - 08:45
TYS
-
MAN
21h 00m
2 stops
£618United Airlines
Thu, 19 Feb - Mon, 23 Feb
Virgin Atlantic Logo
13:30 - 23:52
MAN
-
TYS
15h 22m
1 stop
Virgin Atlantic Logo
11:18 - 10:10
TYS
-
MAN
18h 52m
2 stops
£620Virgin Atlantic
Wed, 4 Mar - Wed, 18 Mar
Virgin Atlantic Logo
13:30 - 23:57
MAN
-
TYS
14h 27m
1 stop
Virgin Atlantic Logo
18:38 - 10:30
TYS
-
MAN
11h 52m
1 stop
£627Virgin Atlantic
Thu, 12 Mar - Thu, 19 Mar
Virgin Atlantic Logo
13:30 - 17:45
MAN
-
TYS
32h 15m
1 stop
Virgin Atlantic Logo
17:10 - 12:45
TYS
-
MAN
15h 35m
2 stops
£652Virgin Atlantic
Thu, 12 Mar - Thu, 19 Mar
United Airlines Logo
10:35 - 10:50
MAN
-
TYS
29h 15m
2 stops
United Airlines Logo
09:40 - 17:20
TYS
-
MAN
26h 40m
2 stops
£654United Airlines
Sat, 25 Apr - Sun, 3 May
British Airways Logo
16:45 - 22:25
MAN
-
TYS
34h 40m
2 stops
British Airways Logo
18:38 - 21:30
TYS
-
MAN
21h 52m
2 stops
£683British Airways
Sat, 25 Apr - Sun, 3 May
British Airways Logo
18:10 - 21:35
MAN
-
TYS
32h 25m
2 stops
British Airways Logo
18:38 - 22:35
TYS
-
MAN
22h 57m
2 stops
£684British Airways
Sat, 25 Apr - Sun, 3 May
United Airlines Logo
05:55 - 20:45
MAN
-
TYS
43h 50m
3 stops
United Airlines Logo
07:00 - 09:50
TYS
-
MAN
21h 50m
2 stops
£693United Airlines
Fri, 1 May - Fri, 8 May
Delta Logo
15:20 - 09:24
MAN
-
TYS
23h 04m
2 stops
Delta Logo
07:30 - 07:15
TYS
-
MAN
18h 45m
1 stop
£697Delta
Sat, 25 Apr - Sun, 3 May

British Airways flights from Manchester to Knoxville

Our best British Airways deals on Manchester to Knoxville flight tickets
British Airways
25 Apr
MAN16:45Manchester
34h 40m
2 stops
TYS22:25Knoxville McGhee Tyson
3 May
TYS18:38Knoxville McGhee Tyson
21h 52m
2 stops
MAN21:30Manchester
£683
British Airways
25 Apr
MAN18:10Manchester
32h 25m
2 stops
TYS21:35Knoxville McGhee Tyson
3 May
TYS18:38Knoxville McGhee Tyson
22h 57m
2 stops
MAN22:35Manchester
£684
British Airways
19 Feb
MAN11:40Manchester
15h 15m
2 stops
TYS21:55Knoxville McGhee Tyson
23 Feb
TYS16:02Knoxville McGhee Tyson
19h 28m
2 stops
MAN16:30Manchester
£725

Virgin Atlantic flights from Manchester to Knoxville

Our best Virgin Atlantic deals on Manchester to Knoxville flight tickets
Virgin Atlantic
4 Mar
MAN13:30Manchester
15h 22m
1 stop
TYS23:52Knoxville McGhee Tyson
18 Mar
TYS15:13Knoxville McGhee Tyson
15h 17m
1 stop
MAN10:30Manchester
£597
Virgin Atlantic
2 Feb
MAN09:00Manchester
19h 45m
1 stop
TYS23:45Knoxville McGhee Tyson
10 Feb
TYS17:00Knoxville McGhee Tyson
18h 05m
2 stops
MAN16:05Manchester
£617
Virgin Atlantic
4 Mar
MAN13:30Manchester
15h 22m
1 stop
TYS23:52Knoxville McGhee Tyson
18 Mar
TYS11:18Knoxville McGhee Tyson
18h 52m
2 stops
MAN10:10Manchester
£620

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 28 January 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 4/3

13:30-23:52

1 stop15h 22m

Knoxville McGhee Tyson

Wed 18/3

15:13-10:30

1 stop15h 17m

£597

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 19/2

13:00-10:49

2 stops26h 49m

Knoxville McGhee Tyson

Mon 23/2

06:45-08:45

2 stops21h 00m

£618

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 4/3

13:30-23:52

1 stop15h 22m

Knoxville McGhee Tyson

Wed 18/3

11:18-10:10

2 stops18h 52m

£620

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 12/3

13:30-23:57

1 stop14h 27m

Knoxville McGhee Tyson

Thu 19/3

18:38-10:30

1 stop11h 52m

£627

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 12/3

13:30-17:45

1 stop32h 15m

Knoxville McGhee Tyson

Thu 19/3

17:10-12:45

2 stops15h 35m

£652

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

10:35-10:50

2 stops29h 15m

Knoxville McGhee Tyson

Sun 3/5

09:40-17:20

2 stops26h 40m

£654

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

16:45-22:25

2 stops34h 40m

Knoxville McGhee Tyson

Sun 3/5

18:38-21:30

2 stops21h 52m

£683

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

18:10-21:35

2 stops32h 25m

Knoxville McGhee Tyson

Sun 3/5

18:38-22:35

2 stops22h 57m

£684

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Fri 1/5

05:55-20:45

3 stops43h 50m

Knoxville McGhee Tyson

Fri 8/5

07:00-09:50

2 stops21h 50m

£693

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

15:20-09:24

2 stops23h 04m

Knoxville McGhee Tyson

Sun 3/5

07:30-07:15

1 stop18h 45m

£697

Flights are sorted by cheapest return flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of March is, on average, the cheapest month to fly to Knoxville from Manchester, with most prices found around £636. If you aren’t able to travel to Knoxville during the month of March, then flying in January is also cheap. Prices for this month can be found on momondo for an average of £646.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around £728 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester for as low as £600 on momondo.

Can stopping save me money on Manchester to Knoxville flights?

You could potentially save up to 1% on your flight if you consider stops on a Manchester to Knoxville flight.

When to book flights from Manchester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville

Fastest flight time

15h 15m

Direct flights

None
The fastest flight from Manchester to Knoxville takes 15h 15m
There are no direct flights from Manchester to Knoxville. There are no popular flight routes from Manchester to Knoxville.
Search flight deals

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 15h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Knoxville?

Best airlines flying from Manchester to Knoxville

Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom £534Free CancellationRating
7.4
9,209 reviews
Search United Airlines flights
British AirwaysPriceFrom £557Free CancellationRating
6.7
7,704 reviews
Search British Airways flights
Virgin AtlanticPriceFrom £564Free CancellationRating
7.5
678 reviews
Search Virgin Atlantic flights
FinnairPriceFrom £567Free CancellationRating
7.6
1,356 reviews
Search Finnair flights
DeltaPriceFrom £692Free CancellationRating
7.9
8,123 reviews
Search Delta flights

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Newport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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