Cheap flights from Manchester to Knoxville from £582
This is the cheapest return flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Find the cheapest flights from Manchester to Knoxville
Cheap return flights
Cheap one-way flights
Save money when you book flights with momondo
Big names, great deals
Big names, great deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customise your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Scandinavian Airlines flights from Manchester to Knoxville
Our best Scandinavian Airlines deals on Manchester to Knoxville flight tickets
United Airlines flights from Manchester to Knoxville
Our best United Airlines deals on Manchester to Knoxville flight tickets
momondo Fare Finder
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Mon 11/1
10:10-23:46
2 stops18h 36m
Knoxville McGhee Tyson
Sun 24/1
16:00-18:35
2 stops21h 35m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Tue 12/1
19:15-23:46
2 stops33h 31m
Knoxville McGhee Tyson
Sun 24/1
17:57-09:30
2 stops34h 33m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Sun 10/1
19:15-23:46
2 stops33h 31m
Knoxville McGhee Tyson
Sun 24/1
17:57-18:35
2 stops19h 38m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Tue 12/1
12:40-09:12
1 stop25h 32m
Knoxville McGhee Tyson
Thu 21/1
10:05-10:05
2 stops19h 00m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Tue 12/1
12:40-09:12
1 stop25h 32m
Knoxville McGhee Tyson
Mon 25/1
08:47-10:05
2 stops20h 18m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Wed 13/1
12:40-11:06
1 stop27h 26m
Knoxville McGhee Tyson
Thu 21/1
10:05-10:05
2 stops19h 00m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Tue 12/1
07:35-18:42
2 stops16h 07m
Knoxville McGhee Tyson
Thu 21/1
17:15-14:15
2 stops16h 00m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Sun 10/1
19:55-18:42
2 stops27h 47m
Knoxville McGhee Tyson
Mon 25/1
16:20-11:45
2 stops14h 25m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Sun 10/1
19:55-18:42
2 stops27h 47m
Knoxville McGhee Tyson
Tue 26/1
17:15-16:30
2 stops18h 15m
ManchesterKnoxville
MAN Manchester - TYS Knoxville McGhee Tyson
MANTYS
Manchester
Thu 11/2
14:55-18:13
1 stop32h 18m
Knoxville McGhee Tyson
Thu 18/2
17:57-10:50
1 stop11h 53m
See travel insights to Knoxville from
How to get the cheapest flight ticket from Manchester to Knoxville
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
When to book flights from Manchester to Knoxville
Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville
Frequently asked questions about flying from Manchester to Knoxville
How far is Manchester to Knoxville McGhee Tyson by plane?
Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 18h 36m is a normal flight duration for this route.
When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.
How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?
There are 3 operators available for flights from Manchester Airport to Knoxville McGhee Tyson Airport as of October 2026.
How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Manchester to Knoxville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Manchester to Knoxville is Virgin Atlantic (83% of total bookings). The next most popular airlines are Delta (9%) and British Airways (8%).
Best airlines flying from Manchester to Knoxville
Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom £603 | Free Cancellation | Rating 6.7 8,259 reviews | |||
| PriceFrom £655 | Free Cancellation | Rating 7.5 694 reviews | |||
| PriceFrom £718 | Free Cancellation | Rating 7.8 8,653 reviews |
Travelling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Manchester to Knoxville?
We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.
Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?
momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.
How can momondo help me find flights from Manchester to Knoxville?
momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.
I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?
Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.