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Cheap flights from Manchester to Knoxville from £543

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Knoxville departing on 8/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap return flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
08:10 - 19:42
MAN
-
TYS
16h 32m
2 stops
Multiple Airlines Logo
17:55 - 20:25
TYS
-
MAN
21h 30m
2 stops
£765Multiple Airlines
Thu, 23 Apr - Thu, 30 Apr
British Airways Logo
07:55 - 21:15
MAN
-
TYS
18h 20m
2 stops
British Airways Logo
13:22 - 09:45
TYS
-
MAN
15h 23m
2 stops
£780British Airways
Tue, 15 Sep - Thu, 24 Sep
Virgin Atlantic Logo
13:00 - 20:06
MAN
-
TYS
12h 06m
1 stop
Virgin Atlantic Logo
07:50 - 08:20
TYS
-
MAN
19h 30m
2 stops
£798Virgin Atlantic
Thu, 23 Apr - Thu, 30 Apr
Virgin Atlantic Logo
13:00 - 23:54
MAN
-
TYS
15h 54m
1 stop
Virgin Atlantic Logo
15:01 - 08:50
TYS
-
MAN
12h 49m
1 stop
£805Virgin Atlantic
Thu, 23 Apr - Thu, 30 Apr
American Airlines Logo
16:35 - 20:00
MAN
-
TYS
32h 25m
2 stops
American Airlines Logo
18:54 - 19:00
TYS
-
MAN
19h 06m
2 stops
£806American Airlines
Sun, 10 May - Tue, 19 May
Virgin Atlantic Logo
13:00 - 20:42
MAN
-
TYS
12h 42m
1 stop
Virgin Atlantic Logo
19:20 - 22:20
TYS
-
MAN
22h 00m
2 stops
£808Virgin Atlantic
Tue, 15 Sep - Thu, 24 Sep
Lufthansa Logo
11:25 - 10:06
MAN
-
TYS
27h 41m
2 stops
Lufthansa Logo
17:55 - 10:25
TYS
-
MAN
35h 30m
2 stops
£811Lufthansa
Wed, 13 May - Wed, 20 May
Virgin Atlantic Logo
13:00 - 20:42
MAN
-
TYS
12h 42m
1 stop
Virgin Atlantic Logo
12:00 - 08:50
TYS
-
MAN
15h 50m
1 stop
£812Virgin Atlantic
Tue, 15 Sep - Thu, 24 Sep
Lufthansa Logo
10:35 - 22:34
MAN
-
TYS
16h 59m
2 stops
Lufthansa Logo
19:18 - 09:50
TYS
-
MAN
33h 32m
2 stops
£817Lufthansa
Sat, 25 Apr - Sun, 3 May
Lufthansa Logo
06:00 - 10:06
MAN
-
TYS
33h 06m
2 stops
Lufthansa Logo
19:18 - 17:10
TYS
-
MAN
16h 52m
2 stops
£819Lufthansa
Mon, 11 May - Mon, 18 May

Virgin Atlantic flights from Manchester to Knoxville

Our best Virgin Atlantic deals on Manchester to Knoxville flight tickets
Virgin Atlantic
23 Apr
MAN13:00Manchester
12h 06m
1 stop
TYS20:06Knoxville McGhee Tyson
30 Apr
TYS07:50Knoxville McGhee Tyson
19h 30m
2 stops
MAN08:20Manchester
£798
Virgin Atlantic
23 Apr
MAN13:00Manchester
15h 54m
1 stop
TYS23:54Knoxville McGhee Tyson
30 Apr
TYS15:01Knoxville McGhee Tyson
12h 49m
1 stop
MAN08:50Manchester
£805
Virgin Atlantic
15 Sept
MAN13:00Manchester
12h 42m
1 stop
TYS20:42Knoxville McGhee Tyson
24 Sept
TYS19:20Knoxville McGhee Tyson
22h 00m
2 stops
MAN22:20Manchester
£808

Delta flights from Manchester to Knoxville

Our best Delta deals on Manchester to Knoxville flight tickets
Delta
11 May
MAN13:00Manchester
27h 09m
1 stop
TYS11:09Knoxville McGhee Tyson
18 May
TYS08:35Knoxville McGhee Tyson
19h 15m
1 stop
MAN08:50Manchester
£841
Delta
25 Apr
MAN14:55Manchester
23h 27m
2 stops
TYS09:22Knoxville McGhee Tyson
3 May
TYS10:05Knoxville McGhee Tyson
16h 10m
1 stop
MAN07:15Manchester
£857
Delta
25 Apr
MAN05:55Manchester
22h 04m
2 stops
TYS22:59Knoxville McGhee Tyson
3 May
TYS05:40Knoxville McGhee Tyson
20h 35m
1 stop
MAN07:15Manchester
£858

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 30 March 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 23/4

08:10-19:42

2 stops16h 32m

Knoxville McGhee Tyson

Thu 30/4

17:55-20:25

2 stops21h 30m

£765

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 15/9

07:55-21:15

2 stops18h 20m

Knoxville McGhee Tyson

Thu 24/9

13:22-09:45

2 stops15h 23m

£780

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 23/4

13:00-20:06

1 stop12h 06m

Knoxville McGhee Tyson

Thu 30/4

07:50-08:20

2 stops19h 30m

£798

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Thu 23/4

13:00-23:54

1 stop15h 54m

Knoxville McGhee Tyson

Thu 30/4

15:01-08:50

1 stop12h 49m

£805

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sun 10/5

16:35-20:00

2 stops32h 25m

Knoxville McGhee Tyson

Tue 19/5

18:54-19:00

2 stops19h 06m

£806

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 15/9

13:00-20:42

1 stop12h 42m

Knoxville McGhee Tyson

Thu 24/9

19:20-22:20

2 stops22h 00m

£808

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Wed 13/5

11:25-10:06

2 stops27h 41m

Knoxville McGhee Tyson

Wed 20/5

17:55-10:25

2 stops35h 30m

£811
Fastest return journey

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Tue 15/9

13:00-20:42

1 stop12h 42m

Knoxville McGhee Tyson

Thu 24/9

12:00-08:50

1 stop15h 50m

£812

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Sat 25/4

10:35-22:34

2 stops16h 59m

Knoxville McGhee Tyson

Sun 3/5

19:18-09:50

2 stops33h 32m

£817

ManchesterKnoxville

MAN - TYS

MANTYS

Manchester

Mon 11/5

06:00-10:06

2 stops33h 06m

Knoxville McGhee Tyson

Mon 18/5

19:18-17:10

2 stops16h 52m

£819

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of November is, on average, the cheapest month to fly to Knoxville from Manchester, with most prices found around £684. If you aren’t able to travel to Knoxville during the month of November, then flying in April is also cheap. Prices for this month can be found on momondo for an average of £700.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around £768 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester for as low as £621 on momondo.

Can stopping save me money on Manchester to Knoxville flights?

You could potentially save up to 12% on your flight if you consider stops on a Manchester to Knoxville flight.

When to book flights from Manchester to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Knoxville (MAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Knoxville

Fastest flight time

20h 47m

Direct flights

None
The fastest flight from Manchester to Knoxville takes 20h 47m
There are no direct flights from Manchester to Knoxville. There are no popular flight routes from Manchester to Knoxville.
Search flight deals

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    Manchester and Knoxville McGhee Tyson are 3949.9 mi apart from one another. 20h 47m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Knoxville?

Best airlines flying from Manchester to Knoxville

Compare and see reviews for airlines that fly from Manchester to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom £553Free CancellationRating
7.4
9,514 reviews
Search United Airlines flights
British AirwaysPriceFrom £577Free CancellationRating
6.7
7,834 reviews
Search British Airways flights
FinnairPriceFrom £587Free CancellationRating
7.7
1,375 reviews
Search Finnair flights
Virgin AtlanticPriceFrom £616Free CancellationRating
7.5
685 reviews
Search Virgin Atlantic flights
DeltaPriceFrom £716Free CancellationRating
7.9
8,359 reviews
Search Delta flights

Travelling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Newport

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to Knoxville for you.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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