Cheap flights from Madrid to Santiago from £346

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Santiago departing on 10/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Air Canada Logo
13:35 - 12:15MAD-SCL
50h 40m2 stops
Air Canada Logo
08:35 - 08:00SCL-MAD
19h 25m1 stop
£595Air Canada
Find Deal
Thu, 4 Dec - Sun, 1 Feb
Delta Logo
11:00 - 07:00MAD-SCL
24h 00m1 stop
Delta Logo
23:15 - 09:00SCL-MAD
29h 45m1 stop
£606Delta
Find Deal
Sun, 2 Nov - Sun, 16 Nov
Delta Logo
10:05 - 07:00MAD-SCL
25h 55m1 stop
Delta Logo
21:40 - 07:50SCL-MAD
53h 10m2 stops
£607Delta
Find Deal
Tue, 16 Sep - Thu, 2 Oct
Delta Logo
11:00 - 07:00MAD-SCL
24h 00m1 stop
Delta Logo
23:15 - 08:00SCL-MAD
28h 45m2 stops
£608Delta
Find Deal
Mon, 3 Nov - Mon, 17 Nov
Delta Logo
12:40 - 07:00MAD-SCL
48h 20m2 stops
Delta Logo
23:15 - 07:00SCL-MAD
27h 45m2 stops
£613Delta
Find Deal
Mon, 25 Aug - Sun, 26 Oct
Delta Logo
10:05 - 07:00MAD-SCL
25h 55m1 stop
Delta Logo
21:40 - 09:35SCL-MAD
30h 55m1 stop
£613Delta
Find Deal
Wed, 24 Sep - Tue, 21 Oct
Delta Logo
07:30 - 07:00MAD-SCL
28h 30m2 stops
Delta Logo
21:40 - 07:50SCL-MAD
53h 10m2 stops
£616Delta
Find Deal
Thu, 18 Sep - Fri, 3 Oct
United Airlines Logo
11:05 - 08:50MAD-SCL
49h 45m2 stops
United Airlines Logo
22:45 - 08:05SCL-MAD
29h 20m2 stops
£643United Airlines
Find Deal
Sun, 23 Nov - Fri, 5 Dec
United Airlines Logo
11:05 - 08:50MAD-SCL
49h 45m2 stops
United Airlines Logo
22:45 - 09:15SCL-MAD
30h 30m2 stops
£648United Airlines
Find Deal
Wed, 26 Nov - Mon, 9 Feb
British Airways Logo
11:50 - 12:50MAD-SCL
29h 00m1 stop
British Airways Logo
12:30 - 16:55SCL-MAD
24h 25m1 stop
£649British Airways
Find Deal
Wed, 21 Jan - Thu, 12 Feb

Delta flights from Madrid to Santiago

Our best Delta deals on Madrid to Santiago flight tickets
Delta
2 Nov
MAD11:00Madrid Barajas
24h 00m
1 stop
SCL07:00Santiago Arturo Merino Benitez
16 Nov
SCL23:15Santiago Arturo Merino Benitez
29h 45m
1 stop
MAD09:00Madrid Barajas
Delta
16 Sept
MAD10:05Madrid Barajas
25h 55m
1 stop
SCL07:00Santiago Arturo Merino Benitez
2 Oct
SCL21:40Santiago Arturo Merino Benitez
53h 10m
2 stops
MAD07:50Madrid Barajas
Delta
3 Nov
MAD11:00Madrid Barajas
24h 00m
1 stop
SCL07:00Santiago Arturo Merino Benitez
17 Nov
SCL23:15Santiago Arturo Merino Benitez
28h 45m
2 stops
MAD08:00Madrid Barajas

United Airlines flights from Madrid to Santiago

Our best United Airlines deals on Madrid to Santiago flight tickets
United Airlines
23 Nov
MAD11:05Madrid Barajas
49h 45m
2 stops
SCL08:50Santiago Arturo Merino Benitez
5 Dec
SCL22:45Santiago Arturo Merino Benitez
29h 20m
2 stops
MAD08:05Madrid Barajas
United Airlines
26 Nov
MAD11:05Madrid Barajas
49h 45m
2 stops
SCL08:50Santiago Arturo Merino Benitez
9 Feb
SCL22:45Santiago Arturo Merino Benitez
30h 30m
2 stops
MAD09:15Madrid Barajas

momondo Fare Finder

 
Customise your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 31 July 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 4/12

13:35-12:15

2 stops50h 40m

Santiago Arturo Merino Benitez

Sun 1/2

08:35-08:00

1 stop19h 25m

£595

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 2/11

11:00-07:00

1 stop24h 00m

Santiago Arturo Merino Benitez

Sun 16/11

23:15-09:00

1 stop29h 45m

£606

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 16/9

10:05-07:00

1 stop25h 55m

Santiago Arturo Merino Benitez

Thu 2/10

21:40-07:50

2 stops53h 10m

£607

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 3/11

11:00-07:00

1 stop24h 00m

Santiago Arturo Merino Benitez

Mon 17/11

23:15-08:00

2 stops28h 45m

£608

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 25/8

12:40-07:00

2 stops48h 20m

Santiago Arturo Merino Benitez

Sun 26/10

23:15-07:00

2 stops27h 45m

£613

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 24/9

10:05-07:00

1 stop25h 55m

Santiago Arturo Merino Benitez

Tue 21/10

21:40-09:35

1 stop30h 55m

£613

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 18/9

07:30-07:00

2 stops28h 30m

Santiago Arturo Merino Benitez

Fri 3/10

21:40-07:50

2 stops53h 10m

£616

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 23/11

11:05-08:50

2 stops49h 45m

Santiago Arturo Merino Benitez

Fri 5/12

22:45-08:05

2 stops29h 20m

£643

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 26/11

11:05-08:50

2 stops49h 45m

Santiago Arturo Merino Benitez

Mon 9/2

22:45-09:15

2 stops30h 30m

£648

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 21/1

11:50-12:50

1 stop29h 00m

Santiago Arturo Merino Benitez

Thu 12/2

12:30-16:55

1 stop24h 25m

£649

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Madrid to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from Madrid to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £643. If you aren’t able to travel to Santiago during the month of March, then flying in April is also cheap. Prices for this month can be found on momondo for an average of £695.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart from Madrid to Santiago is on a Wednesday when prices can be found for as low as £633. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Friday is £923.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from Madrid to Santiago when you can find flight prices for as low as £773. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. Flights to Santiago are more costly at midday, with an average ticket price of £853. Departure times at midday fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Madrid Barajas to Santiago Arturo Merino Benitez flight route?

Fly from Madrid Barajas to Santiago Arturo Merino Benitez for the best Madrid Barajas - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Madrid when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around £806 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Madrid for as low as £695 on momondo.

What cabin class options are available on Madrid Barajas to Santiago Arturo Merino Benitez flights?

There are 2 cabin classes available to choose from on Madrid Barajas to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Madrid to Santiago flights?

No. A direct flight is the cheapest option for a flight between Madrid to Santiago.

How have Madrid to Santiago flight prices changed over time?

As of July 2025, prices for Madrid to Santiago flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Madrid to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Madrid to Santiago (MAD to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Santiago

Best price found

£346

Fastest flight time

13h 15m

Direct flights

Every day

Airports in Santiago

1 airport
The best one-way flight to Santiago from Madrid in the past 72 hours is £346. The best return flight deal from Madrid to Santiago found on momondo in the last 72 hours is £595.
The fastest flight from Madrid to Santiago takes 13h 15m
Direct flights go from Madrid to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is Madrid Barajas to Santiago Arturo Merino Benitez by plane?

    Madrid Barajas and Santiago Arturo Merino Benitez are 6644.6 mi apart from one another. 23h 10m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Madrid to Santiago?

  • What is the most popular airline from Madrid to Santiago?


Best airlines flying from Madrid to Santiago

Compare and see reviews for airlines that fly from Madrid to Santiago with momondo
Airline
Rating
Free Cancellation
Price
IberiaPriceFrom £398Free CancellationRating
7.0
2,859 reviews
Search Iberia flights
LATAM AirlinesPriceFrom £517Free CancellationRating
7.5
1,822 reviews
Search LATAM Airlines flights
British AirwaysPriceFrom £520Free CancellationRating
6.6
7,217 reviews
Search British Airways flights
  • LATAM Airlines Flights From Madrid to Santiago

    The lowest priced LATAM Airlines flight from Madrid to Santiago from the last 72 hours was £689. Generally, LATAM Airlines has 28 flights on this route every week with an average price of £1,075. LATAM Airlines is rated 7.5/10 by our users.

  • Iberia Flights From Madrid to Santiago

    Across 2,859 Iberia reviews on momondo, the average score is 7.0/10. Iberia flies from Madrid to Santiago about 25 times each week, with ticket deals ranging from £531 to £1,132. Price data is based on momondo searches in the last 72 hours.


Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Santa Cruz
Valparaíso
Viña del Mar

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Madrid to Santiago for you.

Can I find flights from Madrid to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Madrid to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from Madrid to Santiago?

Once all potential Madrid to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Madrid to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from Madrid and alert you when they change.


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1 adult
Tue 5/8
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