Cheap flights from Rome to Santiago from £424

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Rome to Santiago departing on 25/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags
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Cheap return flights

Enter your travel dates to find the best prices.
Delta Logo
14:45 - 07:15
FCO
-
SCL
22h 30m
1 stop
Delta Logo
20:40 - 07:55
SCL
-
FCO
29h 15m
2 stops
£621Delta
Mon, 1 Jun - Sun, 7 Jun
Delta Logo
13:30 - 07:40
FCO
-
SCL
22h 10m
1 stop
Delta Logo
23:10 - 11:20
SCL
-
FCO
32h 10m
1 stop
£622Delta
Tue, 27 Oct - Thu, 12 Nov
Delta Logo
13:00 - 07:40
FCO
-
SCL
46h 40m
2 stops
Delta Logo
23:10 - 07:45
SCL
-
FCO
28h 35m
2 stops
£623Delta
Wed, 28 Oct - Mon, 16 Nov
Delta Logo
09:00 - 08:15
FCO
-
SCL
28h 15m
2 stops
Delta Logo
20:40 - 07:55
SCL
-
FCO
30h 15m
2 stops
£627Delta
Mon, 7 Sep - Mon, 28 Sep
Delta Logo
13:10 - 07:15
FCO
-
SCL
48h 05m
2 stops
Delta Logo
20:40 - 11:00
SCL
-
FCO
56h 20m
2 stops
£630Delta
Sat, 30 May - Fri, 5 Jun
Delta Logo
10:10 - 08:15
FCO
-
SCL
51h 05m
2 stops
Delta Logo
20:40 - 16:35
SCL
-
FCO
38h 55m
2 stops
£635Delta
Fri, 11 Sep - Sun, 20 Sep
Delta Logo
06:00 - 07:40
FCO
-
SCL
29h 40m
2 stops
Delta Logo
23:10 - 08:15
SCL
-
FCO
29h 05m
1 stop
£639Delta
Thu, 29 Oct - Tue, 17 Nov
Iberia Logo
20:25 - 20:40
FCO
-
SCL
30h 15m
1 stop
Iberia Logo
10:40 - 19:40
SCL
-
FCO
27h 00m
1 stop
£643Iberia
Mon, 1 Jun - Sun, 14 Jun
Delta Logo
14:45 - 07:15
FCO
-
SCL
22h 30m
1 stop
Delta Logo
20:40 - 10:50
SCL
-
FCO
32h 10m
1 stop
£658Delta
Mon, 1 Jun - Sun, 7 Jun
Delta Logo
10:10 - 08:15
FCO
-
SCL
51h 05m
2 stops
Delta Logo
20:40 - 12:40
SCL
-
FCO
35h 00m
1 stop
£664Delta
Fri, 11 Sep - Sat, 19 Sep

Delta flights from Rome to Santiago

Our best Delta deals on Rome to Santiago flight tickets
Delta
1 Jun
FCO14:45Rome Fiumicino
22h 30m
1 stop
SCL07:15Santiago Arturo Merino Benitez
7 Jun
SCL20:40Santiago Arturo Merino Benitez
29h 15m
2 stops
FCO07:55Rome Fiumicino
£621
Delta
27 Oct
FCO13:30Rome Fiumicino
22h 10m
1 stop
SCL07:40Santiago Arturo Merino Benitez
12 Nov
SCL23:10Santiago Arturo Merino Benitez
32h 10m
1 stop
FCO11:20Rome Fiumicino
£622
Delta
28 Oct
FCO13:00Rome Fiumicino
46h 40m
2 stops
SCL07:40Santiago Arturo Merino Benitez
16 Nov
SCL23:10Santiago Arturo Merino Benitez
28h 35m
2 stops
FCO07:45Rome Fiumicino
£623

Iberia flights from Rome to Santiago

Our best Iberia deals on Rome to Santiago flight tickets
Iberia
1 Jun
FCO20:25Rome Fiumicino
30h 15m
1 stop
SCL20:40Santiago Arturo Merino Benitez
14 Jun
SCL10:40Santiago Arturo Merino Benitez
27h 00m
1 stop
FCO19:40Rome Fiumicino
£643
Iberia
1 Jun
FCO07:35Rome Fiumicino
19h 05m
1 stop
SCL20:40Santiago Arturo Merino Benitez
3 Jul
SCL10:40Santiago Arturo Merino Benitez
19h 55m
1 stop
FCO12:35Rome Fiumicino
£768

momondo Fare Finder

 
Customise your flight search to find flights from Rome to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 13 May 2026.
Use the filters below to find and compare flights from Rome to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 1/6

14:45-07:15

1 stop22h 30m

Santiago Arturo Merino Benitez

Sun 7/6

20:40-07:55

2 stops29h 15m

£621

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Tue 27/10

13:30-07:40

1 stop22h 10m

Santiago Arturo Merino Benitez

Thu 12/11

23:10-11:20

1 stop32h 10m

£622

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Wed 28/10

13:00-07:40

2 stops46h 40m

Santiago Arturo Merino Benitez

Mon 16/11

23:10-07:45

2 stops28h 35m

£623

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 7/9

09:00-08:15

2 stops28h 15m

Santiago Arturo Merino Benitez

Mon 28/9

20:40-07:55

2 stops30h 15m

£627

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Sat 30/5

13:10-07:15

2 stops48h 05m

Santiago Arturo Merino Benitez

Fri 5/6

20:40-11:00

2 stops56h 20m

£630

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Fri 11/9

10:10-08:15

2 stops51h 05m

Santiago Arturo Merino Benitez

Sun 20/9

20:40-16:35

2 stops38h 55m

£635

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Thu 29/10

06:00-07:40

2 stops29h 40m

Santiago Arturo Merino Benitez

Tue 17/11

23:10-08:15

1 stop29h 05m

£639

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 1/6

20:25-20:40

1 stop30h 15m

Santiago Arturo Merino Benitez

Sun 14/6

10:40-19:40

1 stop27h 00m

£643

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Mon 1/6

14:45-07:15

1 stop22h 30m

Santiago Arturo Merino Benitez

Sun 7/6

20:40-10:50

1 stop32h 10m

£658

RomeSantiago

FCO - SCL

FCOSCL

Rome Fiumicino

Fri 11/9

10:10-08:15

2 stops51h 05m

Santiago Arturo Merino Benitez

Sat 19/9

20:40-12:40

1 stop35h 00m

£664

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Rome to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Rome and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Rome to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £273. If you aren’t able to travel to Santiago during the month of May, then flying in September is also cheap. Prices for this month can be found on momondo for an average of £516.

How have Rome to Santiago flight prices changed over time?

As of May 2026, prices for Rome to Santiago flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from Rome to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Rome to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Rome to Santiago (ROM to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rome to Santiago

Fastest flight time

21h 10m

Direct flights

None
The fastest flight from Rome to Santiago takes 21h 10m
There are no direct flights from Rome to Santiago. There are no popular flight routes from Rome to Santiago.

Frequently asked questions about flying from Rome to Santiago

  • How far is Rome to Santiago Arturo Merino Benitez by plane?

    A flight from Rome to Santiago Arturo Merino Benitez will travel around 7394.8 mi. Flights usually cover this in 21h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Rome to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Rome to Santiago Arturo Merino Benitez Airport refresh daily.

  • How old do you have to be to fly from Rome to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Rome to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Santa Cruz
Valparaíso

Why use momondo?

Why should I use momondo to find a flight deal from Rome to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Rome to Santiago . Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Rome to Santiago with flexible booking policies on momondo?

Yes. All flights to Santiago from Rome on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Rome to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Rome.

I’m not ready to book a flight from Rome to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Rome to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.

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1 adult
Fri 12/6
Fri 19/6

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