Cheap flights from New York LaGuardia Airport to St. Louis from £109

The month of October is, on average, the cheapest month to fly to St. Louis from New York LaGuardia Airport, with most prices found around £260. If you’re not able to fly to St. Louis in October, then April is your next best option. Flight prices from New York LaGuardia Airport to St. Louis during April average around £263.

Our data shows that Tuesday is the least expensive day to fly to St. Louis. Tickets to fly out on this day can be as low as £208. Flights from New York LaGuardia Airport to St. Louis on a Friday will generally be more expensive and average around £334. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Our data shows that the cheapest New York LaGuardia Airport to St. Louis flights are usually those with departure times in the afternoon. Our users have found flights to St. Louis in the afternoon for as low as £208. In contrast, the most expensive time of day to depart to St. Louis is in the morning when prices are around £334.

Fly from New York LaGuardia to Lambert-St Louis for the best New York LaGuardia - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from New York LaGuardia Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around £305 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from New York LaGuardia Airport for as low as £192 on momondo.

There is only 1 cabin class available to choose from on New York LaGuardia Airport to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

As of September 2026, there are 6 flights per day flying from New York LaGuardia Airport to St. Louis. The most common time of day flights depart is 18:00, with 36% of flights taking off in the afternoon.

As of September 2026, 42 flights take off from New York LaGuardia Airport and land in St. Louis each week. The most common flight departure day for this route is Fri, with 33% of weekly flights taking off on this day.