Cheap flights from Lisbon to São Tomé and Príncipe from £409

The month of April is, on average, the cheapest month to fly to São Tomé and Príncipe from Lisbon, with most prices found around £175. If you’re not able to fly to São Tomé and Príncipe in April, then November is your next best option. Flight prices from Lisbon to São Tomé and Príncipe during November average around £202.

The cheapest day to depart from Lisbon to São Tomé and Príncipe is on a Thursday when prices can be found for as low as £489. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around £819. These prices are subject to change though, so be sure to set up a Price Alert for flights to São Tomé and Príncipe.

Our most recent data shows that the best time of day to fly to São Tomé and Príncipe is in the morning. Flights from Lisbon to São Tomé and Príncipe during this time can be as low as £654. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are £716 on average. Flights to São Tomé and Príncipe from Lisbon in the evening are generally more expensive because this time of day is more convenient for travellers’ schedules.

Fly from Lisbon Humberto Delgado to Sao Tome Is for the best Lisbon Humberto Delgado - São Tomé and Príncipe flight prices

You are more likely to see cheaper flights to São Tomé and Príncipe from Lisbon when booking weeks ahead of your departure date. In general, you can expect to find flights to São Tomé and Príncipe for around £588 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to São Tomé and Príncipe from Lisbon for as low as £541 on momondo.

TAP AIR PORTUGAL, EuroAtlantic Airways, and STP Airways are the most popular carriers operating from Lisbon Humberto Delgado to São Tomé and Príncipe

TAP AIR PORTUGAL, TAAG and STP Airways are the top three most popular airlines that fly to São Tomé and Príncipe from Lisbon according to our data. TAP AIR PORTUGAL is the first choice among our users, with 41% of people opting to fly with this airline when travelling to São Tomé and Príncipe. Keep in mind that there are 4 different airlines that fly to São Tomé and Príncipe on a routine basis, so you have a few additional options to choose from.

Historically, on average around 45% of flights between Lisbon and São Tomé and Príncipe have experienced a delay on any given week. The average delay length over the past 12 months has been 115 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights departing in the early afternoon have, in the past, seen delays more frequently in comparison.

Friday is statistically the day of the week that experiences the fewest delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, TAP AIR PORTUGAL have had the fewest delays on this route over the last 12 months, with about 34% of their flights experiencing any sort of delay.

As of May 2026, there are 1 flights per day flying from Lisbon to São Tomé and Príncipe. The most common time of day flights depart is 09:00, with 77% of flights taking off at midday.

As of May 2026, 9 flights take off from Lisbon and land in São Tomé and Príncipe each week. The most common flight departure day for this route is Sat, with 33% of weekly flights taking off on this day.