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Cheap flights from Manchester to Des Moines from £280

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Des Moines departing on 22/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap return flights

Enter your travel dates to find the best prices.
Scandinavian Airlines Logo
09:35 - 22:32
MAN
-
DSM
18h 57m
2 stops
Scandinavian Airlines Logo
14:15 - 08:55
DSM
-
MAN
36h 40m
2 stops
£613Scandinavian Airlines
Sat, 30 May - Mon, 15 Jun
Scandinavian Airlines Logo
09:35 - 22:32
MAN
-
DSM
18h 57m
2 stops
Scandinavian Airlines Logo
14:15 - 08:55
DSM
-
MAN
36h 40m
2 stops
£617Scandinavian Airlines
Sat, 30 May - Mon, 15 Jun
Scandinavian Airlines Logo
09:35 - 22:32
MAN
-
DSM
18h 57m
2 stops
Scandinavian Airlines Logo
14:15 - 08:55
DSM
-
MAN
36h 40m
2 stops
£660Scandinavian Airlines
Mon, 1 Jun - Mon, 15 Jun
Scandinavian Airlines Logo
09:35 - 22:32
MAN
-
DSM
18h 57m
2 stops
Scandinavian Airlines Logo
14:15 - 18:30
DSM
-
MAN
22h 15m
2 stops
£721Scandinavian Airlines
Mon, 1 Jun - Mon, 15 Jun
Scandinavian Airlines Logo
09:35 - 22:32
MAN
-
DSM
18h 57m
2 stops
Scandinavian Airlines Logo
14:15 - 08:55
DSM
-
MAN
36h 40m
2 stops
£722Scandinavian Airlines
Mon, 1 Jun - Mon, 15 Jun
United Airlines Logo
09:25 - 22:20
MAN
-
DSM
18h 55m
2 stops
United Airlines Logo
13:32 - 12:20
DSM
-
MAN
16h 48m
2 stops
£906United Airlines
Thu, 26 Feb - Mon, 2 Mar
United Airlines Logo
09:25 - 20:07
MAN
-
DSM
16h 42m
2 stops
United Airlines Logo
11:30 - 08:45
DSM
-
MAN
15h 15m
2 stops
£907United Airlines
Thu, 26 Feb - Mon, 2 Mar
Multiple Airlines Logo
08:10 - 23:54
MAN
-
DSM
21h 44m
2 stops
Multiple Airlines Logo
06:00 - 06:30
DSM
-
MAN
18h 30m
2 stops
£947Multiple Airlines
Tue, 2 Jun - Tue, 16 Jun
Aer Lingus Logo
20:55 - 23:54
MAN
-
DSM
32h 59m
2 stops
Aer Lingus Logo
06:00 - 07:40
DSM
-
MAN
19h 40m
2 stops
£978Aer Lingus
Tue, 2 Jun - Tue, 16 Jun
Multiple Airlines Logo
13:00 - 22:32
MAN
-
DSM
15h 32m
1 stop
Multiple Airlines Logo
06:00 - 06:30
DSM
-
MAN
18h 30m
2 stops
£989Multiple Airlines
Tue, 2 Jun - Tue, 16 Jun

Virgin Atlantic flights from Manchester to Des Moines

Our best Virgin Atlantic deals on Manchester to Des Moines flight tickets
Virgin Atlantic
2 Jun
MAN13:00Manchester
15h 32m
1 stop
DSM22:32Des Moines
16 Jun
DSM14:15Des Moines
12h 35m
1 stop
MAN08:50Manchester
£1,034
Virgin Atlantic
30 May
MAN13:15Manchester
34h 38m
1 stop
DSM17:53Des Moines
15 Jun
DSM11:04Des Moines
15h 46m
1 stop
MAN08:50Manchester
£1,064

Delta flights from Manchester to Des Moines

Our best Delta deals on Manchester to Des Moines flight tickets
Delta
1 Jun
MAN13:00Manchester
28h 03m
1 stop
DSM11:03Des Moines
15 Jun
DSM05:45Des Moines
21h 05m
1 stop
MAN08:50Manchester
£1,066
Delta
1 Jun
MAN13:00Manchester
15h 32m
1 stop
DSM22:32Des Moines
15 Jun
DSM05:45Des Moines
21h 05m
1 stop
MAN08:50Manchester
£1,067

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 5 February 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Sat 30/5

09:35-22:32

2 stops18h 57m

Des Moines

Mon 15/6

14:15-08:55

2 stops36h 40m

£613

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Sat 30/5

09:35-22:32

2 stops18h 57m

Des Moines

Mon 15/6

14:15-08:55

2 stops36h 40m

£617

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

09:35-22:32

2 stops18h 57m

Des Moines

Mon 15/6

14:15-08:55

2 stops36h 40m

£660

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

09:35-22:32

2 stops18h 57m

Des Moines

Mon 15/6

14:15-18:30

2 stops22h 15m

£721

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

09:35-22:32

2 stops18h 57m

Des Moines

Mon 15/6

14:15-08:55

2 stops36h 40m

£722

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Thu 26/2

09:25-22:20

2 stops18h 55m

Des Moines

Mon 2/3

13:32-12:20

2 stops16h 48m

£906

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Thu 26/2

09:25-20:07

2 stops16h 42m

Des Moines

Mon 2/3

11:30-08:45

2 stops15h 15m

£907

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

08:10-23:54

2 stops21h 44m

Des Moines

Tue 16/6

06:00-06:30

2 stops18h 30m

£947

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

20:55-23:54

2 stops32h 59m

Des Moines

Tue 16/6

06:00-07:40

2 stops19h 40m

£978

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

13:00-22:32

1 stop15h 32m

Des Moines

Tue 16/6

06:00-06:30

2 stops18h 30m

£989

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Manchester to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester and Des Moines?

What is the cheapest month to fly to Des Moines?

In general, January is the cheapest month to fly from Manchester to Des Moines. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £559. If you don’t want to visit Des Moines in January, then you should wait until November to fly from Manchester, when ticket prices are also cheap, with an average price of £731.

Can stopping save me money on Manchester to Des Moines flights?

You could potentially save up to 41% on your flight if you consider stops on a Manchester to Des Moines flight.

When to book flights from Manchester to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Des Moines (MAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Des Moines

Fastest flight time

16h 42m

Direct flights

None
The fastest flight from Manchester to Des Moines takes 16h 42m
There are no direct flights from Manchester to Des Moines. There are no popular flight routes from Manchester to Des Moines.
Search flight deals

  • How far is Manchester to Des Moines by plane?

    A flight from Manchester to Des Moines will travel around 4038.6 mi. 16h 42m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Des Moines Airport?

    Prices for flights from Manchester Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Manchester Airport to Des Moines Airport?

  • How old do you have to be to fly from Manchester Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Des Moines?

Best airlines flying from Manchester to Des Moines

Compare and see reviews for airlines that fly from Manchester to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
British AirwaysPriceFrom £660Free CancellationRating
6.7
7,716 reviews
Search British Airways flights
Virgin AtlanticPriceFrom £760Free CancellationRating
7.5
678 reviews
Search Virgin Atlantic flights
KLMPriceFrom £805Free CancellationRating
7.7
1,449 reviews
Search KLM flights
Aer LingusPriceFrom £916Free CancellationRating
7.2
1,445 reviews
Search Aer Lingus flights

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Des Moines?

It is quick and easy to find Manchester to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Manchester to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Manchester on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Manchester to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Manchester.

I’m not ready to book a flight from Manchester to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Manchester to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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