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Cheap flights from Manchester to Des Moines from £349

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to Des Moines departing on 22/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Manchester to Des Moines

Cheap return flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:35 - 21:23
MAN
-
DSM
16h 48m
2 stops
United Airlines Logo
05:00 - 09:50
DSM
-
MAN
22h 50m
2 stops
£943United Airlines
Mon, 4 May - Mon, 11 May
Multiple Airlines Logo
20:55 - 18:36
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
13:48 - 13:55
DSM
-
MAN
18h 07m
2 stops
£974Multiple Airlines
Tue, 2 Jun - Tue, 16 Jun
Multiple Airlines Logo
20:55 - 18:36
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
13:48 - 13:55
DSM
-
MAN
18h 07m
2 stops
£976Multiple Airlines
Tue, 2 Jun - Tue, 16 Jun
Multiple Airlines Logo
20:55 - 18:36
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
13:46 - 13:55
DSM
-
MAN
18h 09m
2 stops
£984Multiple Airlines
Tue, 2 Jun - Tue, 16 Jun
Multiple Airlines Logo
20:55 - 18:36
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
05:15 - 08:40
DSM
-
MAN
21h 25m
2 stops
£991Multiple Airlines
Mon, 1 Jun - Mon, 15 Jun
Multiple Airlines Logo
20:55 - 18:36
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
05:15 - 07:40
DSM
-
MAN
20h 25m
2 stops
£992Multiple Airlines
Mon, 1 Jun - Mon, 15 Jun
Multiple Airlines Logo
20:55 - 18:36
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
05:15 - 08:40
DSM
-
MAN
21h 25m
2 stops
£994Multiple Airlines
Mon, 1 Jun - Mon, 15 Jun
Lufthansa Logo
06:05 - 15:48
MAN
-
DSM
15h 43m
2 stops
Lufthansa Logo
18:50 - 10:25
DSM
-
MAN
33h 35m
2 stops
£996Lufthansa
Tue, 2 Jun - Tue, 16 Jun
Multiple Airlines Logo
20:55 - 18:36
MAN
-
DSM
27h 41m
2 stops
Multiple Airlines Logo
13:46 - 13:55
DSM
-
MAN
18h 09m
2 stops
£1,000Multiple Airlines
Tue, 2 Jun - Tue, 16 Jun
United Airlines Logo
06:05 - 19:26
MAN
-
DSM
19h 21m
2 stops
United Airlines Logo
15:26 - 17:20
DSM
-
MAN
19h 54m
2 stops
£1,004United Airlines
Sat, 2 May - Sat, 9 May

United Airlines flights from Manchester to Des Moines

Our best United Airlines deals on Manchester to Des Moines flight tickets
United Airlines
4 May
MAN10:35Manchester
16h 48m
2 stops
DSM21:23Des Moines
11 May
DSM05:00Des Moines
22h 50m
2 stops
MAN09:50Manchester
£943
United Airlines
2 May
MAN06:05Manchester
19h 21m
2 stops
DSM19:26Des Moines
9 May
DSM15:26Des Moines
19h 54m
2 stops
MAN17:20Manchester
£1,004

Delta flights from Manchester to Des Moines

Our best Delta deals on Manchester to Des Moines flight tickets
Delta
2 Jun
MAN13:00Manchester
15h 32m
1 stop
DSM22:32Des Moines
16 Jun
DSM14:15Des Moines
12h 35m
1 stop
MAN08:50Manchester
£1,112
Delta
1 Jun
MAN13:00Manchester
28h 08m
1 stop
DSM11:08Des Moines
15 Jun
DSM14:35Des Moines
17h 25m
2 stops
MAN14:00Manchester
£1,116
Delta
1 Jun
MAN13:00Manchester
28h 08m
1 stop
DSM11:08Des Moines
15 Jun
DSM14:35Des Moines
17h 25m
2 stops
MAN14:00Manchester
£1,117

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 23 March 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 4/5

10:35-21:23

2 stops16h 48m

Des Moines

Mon 11/5

05:00-09:50

2 stops22h 50m

£943

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

20:55-18:36

2 stops27h 41m

Des Moines

Tue 16/6

13:48-13:55

2 stops18h 07m

£974

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

20:55-18:36

2 stops27h 41m

Des Moines

Tue 16/6

13:48-13:55

2 stops18h 07m

£976

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

20:55-18:36

2 stops27h 41m

Des Moines

Tue 16/6

13:46-13:55

2 stops18h 09m

£984

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

20:55-18:36

2 stops27h 41m

Des Moines

Mon 15/6

05:15-08:40

2 stops21h 25m

£991

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

20:55-18:36

2 stops27h 41m

Des Moines

Mon 15/6

05:15-07:40

2 stops20h 25m

£992

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

20:55-18:36

2 stops27h 41m

Des Moines

Mon 15/6

05:15-08:40

2 stops21h 25m

£994

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

06:05-15:48

2 stops15h 43m

Des Moines

Tue 16/6

18:50-10:25

2 stops33h 35m

£996

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

20:55-18:36

2 stops27h 41m

Des Moines

Tue 16/6

13:46-13:55

2 stops18h 09m

£1,000
Fastest return journey

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Sat 2/5

06:05-19:26

2 stops19h 21m

Des Moines

Sat 9/5

15:26-17:20

2 stops19h 54m

£1,004

Flights are sorted by cheapest return flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Manchester to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester and Des Moines?

What is the cheapest month to fly to Des Moines?

In general, November is the cheapest month to fly from Manchester to Des Moines. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £784. If you don’t want to visit Des Moines in November, then you should wait until October to fly from Manchester, when ticket prices are also cheap, with an average price of £815.

Can stopping save me money on Manchester to Des Moines flights?

You could potentially save up to 7% on your flight if you consider stops on a Manchester to Des Moines flight.

When to book flights from Manchester to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Manchester to Des Moines (MAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to Des Moines

Fastest flight time

16h 48m

Direct flights

None
The fastest flight from Manchester to Des Moines takes 16h 48m
There are no direct flights from Manchester to Des Moines. There are no popular flight routes from Manchester to Des Moines.
Search flight deals

  • How far is Manchester to Des Moines by plane?

    A flight from Manchester to Des Moines will travel around 4038.6 mi. 16h 48m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Manchester Airport to Des Moines Airport?

    Prices for flights from Manchester Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Manchester Airport to Des Moines Airport?

  • How old do you have to be to fly from Manchester Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester to Des Moines?

Best airlines flying from Manchester to Des Moines

Compare and see reviews for airlines that fly from Manchester to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
British AirwaysPriceFrom £784Free CancellationRating
6.7
7,809 reviews
Search British Airways flights
Virgin AtlanticPriceFrom £788Free CancellationRating
7.5
682 reviews
Search Virgin Atlantic flights
Aer LingusPriceFrom £933Free CancellationRating
7.2
1,481 reviews
Search Aer Lingus flights
DeltaPriceFrom £942Free CancellationRating
7.9
8,315 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Des Moines?

It is quick and easy to find Manchester to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Manchester to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Manchester on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Manchester to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Manchester.

I’m not ready to book a flight from Manchester to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Manchester to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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