Cheap flights from Madrid to Brussels from £43

In general, November is the cheapest month to fly from Madrid to Brussels. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £92. If you are unable to visit Brussels during the month of November, then departing from Madrid during the month March is also very affordable. Most momondo users find prices during this month for around £124.

Our data shows that Sunday is the least expensive day to fly to Brussels. Tickets to fly out on this day can be as low as £191. On the other hand, Wednesday is the most expensive day to depart from Madrid because it is more convenient for both business and leisure travellers. As a result, prices tend to be around £619.

According to our data, the cheapest time of day to fly to Brussels is in the evening. momondo users have found flights departing from Madrid to Brussels in the evening for as low as £184. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Brussels, so prices are often more expensive at around £529 per ticket.

Fly from Madrid Barajas to Brussels Bruxelles-National for the best Madrid Barajas - Brussels flight prices

You are more likely to see cheaper flights to Brussels from Madrid when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels for around £130 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels from Madrid for as low as £107 on momondo.

There are 3 cabin classes available to choose from on Madrid to Brussels flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Historically, on average around 17% of flights between Madrid and Brussels have experienced a delay on any given week. The average delay length over the past 12 months has been 112 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights departing in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week that experiences the fewest delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, Iberia have had the fewest delays on this route over the last 12 months, with about 9% of their flights experiencing any sort of delay.

As of April 2026, there are 27 flights per day flying from Madrid to Brussels. The most common time of day flights depart is 09:00, with 46% of flights taking off at midday.

As of April 2026, there are 195 flights per week flying from Madrid to Brussels. The most common day of the week flights depart is Tue, with 17% of flights taking off on this day.