Cheap flights from Lisbon to Madrid from £22

The cheapest month to fly to Region of Madrid from Lisbon is in February. Flight prices, which tend to average around £59, are often lower during this time because this is during the off-season. If you’re not able to fly to Region of Madrid in February, then March is your next best option. Flight prices from Lisbon to Region of Madrid during March average around £64.

On average, the least expensive day to fly to Region of Madrid from Lisbon is on a Friday. momondo users have found tickets for Friday departures for as low as £154. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Tuesday is the most expensive day to depart from Lisbon because it is more convenient for both business and leisure travellers. As a result, prices tend to be around £451.

According to our data, the cheapest time of day to fly to Region of Madrid is in the afternoon. momondo users have found flights departing from Lisbon to Region of Madrid in the afternoon for as low as £160. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are £433 on average. Flights to Region of Madrid from Lisbon in the evening are generally more expensive because this time of day is more convenient for travellers’ schedules.

Fly from Lisbon Humberto Delgado to Madrid Barajas for the best Lisbon Humberto Delgado - Madrid flight prices

You are more likely to see cheaper flights to Region of Madrid from Lisbon when booking weeks ahead of your departure date. In general, you can expect to find flights to Region of Madrid for around £69 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Region of Madrid from Lisbon for as low as £55 on momondo.

There are 3 cabin classes available to choose from on Lisbon Humberto Delgado to Madrid flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

easyJet is the most popular carrier operating from Lisbon Humberto Delgado to Madrid

easyJet, TAP AIR PORTUGAL and Air Europa are the top three most popular airlines that fly to Region of Madrid from Lisbon according to our data. easyJet is the first choice among our users, with 33% of people opting to fly with this airline when travelling to Region of Madrid. Keep in mind that there are 4 different airlines that fly to Region of Madrid on a routine basis, so you have a few additional options to choose from.

The number of flights available between Lisbon and Region of Madrid is 69 per day as of March 2026. The most frequent departure time is 11:00, with 57% of daily flights leaving at midday.

As of March 2026, 487 flights take off from Lisbon and land in Region of Madrid each week. The most common flight departure day for this route is Fri, with 20% of weekly flights taking off on this day.