Cheap flights from Manchester to Prague Region from £21

The month of January is, on average, the cheapest month to fly to Prague Region from Manchester, with most prices found around £90. If you are unable to visit Prague Region during the month of January, then departing from Manchester during the month March is also very affordable. Most momondo users find prices during this month for around £104.

The cheapest day to depart from Manchester to Prague Region is on a Wednesday. Travellers who choose to depart for Prague Region on a Wednesday will often find tickets for as low as £105. On the other hand, Friday is the most expensive day to depart from Manchester because it is more convenient for both business and leisure travellers. As a result, prices tend to be around £139.

Our most recent data shows that the best time of day to fly to Prague Region is in the evening. Flights from Manchester to Prague Region during this time can be as low as £88. In contrast, the most expensive time of day to depart to Prague Region is in the morning when prices are around £125.

Fly from Manchester to Václav Havel Prague for the best Manchester - Prague Region flight prices

You are more likely to see cheaper flights to Prague Region from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to Prague Region for around £122 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Prague Region from Manchester for as low as £103 on momondo.

There is only 1 cabin class available to choose from on Manchester to Prague Region flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Ryanair is the most popular carrier operating from Manchester to Prague Region

Ryanair, easyJet and Jet2 are the top three most popular airlines that fly to Prague Region from Manchester according to our data. Ryanair is the first choice among our users, with 44% of people opting to fly with this airline when travelling to Prague Region. Keep in mind that there are 7 different airlines that fly to Prague Region on a routine basis, so you have a few additional options to choose from.

1 flights are operational daily from Manchester to Prague Region as of August 2026. The most popular departure time for this route is 12:00, with 66% of flights per day taking off in the afternoon.

As of August 2026, there are 7 flights per week flying from Manchester to Prague Region. The most common day of the week flights depart is Mon, with 43% of flights taking off on this day.