Which airlines fly to South Carolina?

Virgin Atlantic, British Airways and American Airlines are the top three most popular airlines that fly to South Carolina from Manchester according to our data. Virgin Atlantic is the first choice among our users, with 77% of people opting to fly with this airline when travelling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Manchester to South Carolina?

United Airlines, Virgin Atlantic, and Delta are the most popular carriers operating from Manchester to South Carolina

When did momondo last update prices for flights from Manchester Airport to South Carolina?

Prices for flights from Manchester Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Manchester Airport to South Carolina?

As of October 2026, there are 5 operators available to choose from for flights from Manchester Airport to South Carolina.

How old do you have to be to fly from Manchester Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

£412 Cheap Flights from Manchester to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Manchester to South Carolina

Return

One-way

Cheap return flights

Enter your travel dates to find the best prices.

10:10 - 23:35MAN Manchester-MYR Myrtle Beach Intl

18h 25m2 stops Kastrup Copenhagen Atlanta Hartsfield-Jackson

14:15 - 09:30MYR Myrtle Beach Intl-MAN Manchester

38h 15m2 stops Atlanta Hartsfield-Jackson Kastrup Copenhagen

£576Scandinavian Airlines

Wed, 10 Feb - Mon, 8 Mar

19:15 - 00:04MAN Manchester-CHS Charleston

33h 49m2 stops Kastrup Copenhagen Atlanta Hartsfield-Jackson

06:00 - 09:30CHS Charleston-MAN Manchester

22h 30m2 stops New York John F Kennedy Intl Kastrup Copenhagen

£584Scandinavian Airlines

Sat, 5 Dec - Sun, 7 Feb

12:40 - 00:04MAN Manchester-CHS Charleston

16h 24m1 stop Atlanta Hartsfield-Jackson

06:00 - 09:40CHS Charleston-MAN Manchester

22h 40m1 stop New York John F Kennedy Intl

£809Virgin Atlantic

Sat, 5 Dec - Sun, 7 Feb

12:40 - 22:25MAN Manchester-CAE Columbia Metropolitan

14h 45m1 stop Atlanta Hartsfield-Jackson

12:00 - 10:30CAE Columbia Metropolitan-MAN Manchester

17h 30m1 stop Atlanta Hartsfield-Jackson

£815Virgin Atlantic

Wed, 13 Jan - Tue, 2 Feb

09:45 - 10:29MAN Manchester-GSP Greenville

29h 44m2 stops London Heathrow Philadelphia

16:06 - 16:30GSP Greenville-MAN Manchester

19h 24m2 stops Philadelphia London Heathrow

£816British Airways

Mon, 7 Dec - Mon, 14 Dec

11:55 - 23:52MAN Manchester-CHS Charleston

16h 57m2 stops London Heathrow Miami

11:32 - 11:45CHS Charleston-MAN Manchester

19h 13m2 stops Miami London Heathrow

£831British Airways

Mon, 23 Nov - Mon, 30 Nov

06:05 - 17:54MAN Manchester-CAE Columbia Metropolitan

16h 49m2 stops London Heathrow Philadelphia

17:15 - 14:55CAE Columbia Metropolitan-MAN Manchester

16h 40m2 stops Chicago O'Hare Intl London Heathrow

£856American Airlines

Wed, 6 Jan - Wed, 27 Jan

14:55 - 11:07MAN Manchester-GSP Greenville

25h 12m1 stop Atlanta Hartsfield-Jackson

08:15 - 10:05GSP Greenville-MAN Manchester

20h 50m2 stops Atlanta Hartsfield-Jackson Paris Charles de Gaulle

£878Delta

Thu, 19 Nov - Thu, 26 Nov

14:55 - 15:01MAN Manchester-MYR Myrtle Beach Intl

29h 06m1 stop Atlanta Hartsfield-Jackson

11:30 - 16:05MYR Myrtle Beach Intl-MAN Manchester

23h 35m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle

£889Delta

Fri, 6 Nov - Mon, 9 Nov

11:55 - 23:58MAN Manchester-CAE Columbia Metropolitan

17h 03m2 stops London Heathrow Chicago O'Hare Intl

20:17 - 16:35CAE Columbia Metropolitan-MAN Manchester

15h 18m2 stops Charlotte Douglas London Heathrow

£901American Airlines

Fri, 4 Dec - Fri, 11 Dec

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Scandinavian Airlines flights from Manchester to South Carolina

Our best Scandinavian Airlines deals on Manchester to South Carolina flight tickets

Scandinavian Airlines

10 Feb

MAN10:10Manchester

18h 25m

2 stops

MYR23:35Myrtle Beach Intl

8 Mar

MYR14:15Myrtle Beach Intl

38h 15m

2 stops

MAN09:30Manchester

£576

Scandinavian Airlines

5 Dec

MAN19:15Manchester

33h 49m

2 stops

CHS00:04Charleston

7 Feb

CHS06:00Charleston

22h 30m

2 stops

MAN09:30Manchester

£584

Scandinavian Airlines

13 Jan

MAN10:10Manchester

17h 15m

2 stops

CAE22:25Columbia Metropolitan

3 Feb

CAE17:10Columbia Metropolitan

20h 25m

2 stops

MAN18:35Manchester

£584

Virgin Atlantic flights from Manchester to South Carolina

Our best Virgin Atlantic deals on Manchester to South Carolina flight tickets

Virgin Atlantic

5 Dec

MAN12:40Manchester

16h 24m

1 stop

CHS00:04Charleston

7 Feb

CHS06:00Charleston

22h 40m

1 stop

MAN09:40Manchester

£809

Virgin Atlantic

13 Jan

MAN12:40Manchester

14h 45m

1 stop

CAE22:25Columbia Metropolitan

2 Feb

CAE12:00Columbia Metropolitan

17h 30m

1 stop

MAN10:30Manchester

£815

Virgin Atlantic

6 Jan

MAN14:55Manchester

30h 33m

2 stops

CAE16:28Columbia Metropolitan

27 Jan

CAE12:00Columbia Metropolitan

16h 40m

2 stops

MAN09:40Manchester

£819

momondo Fare Finder

Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterMyrtle Beach

MAN Manchester - MYR Myrtle Beach Intl

MANMYR

Manchester

Wed 10/2

10:10-23:35

2 stops18h 25m

Myrtle Beach Intl

Mon 8/3

14:15-09:30

2 stops38h 15m

£576

ManchesterCharleston

MAN Manchester - CHS Charleston

MANCHS

Manchester

Sat 5/12

19:15-00:04

2 stops33h 49m

Charleston

Sun 7/2

06:00-09:30

2 stops22h 30m

£584

ManchesterCharleston

MAN Manchester - CHS Charleston

MANCHS

Manchester

Sat 5/12

12:40-00:04

1 stop16h 24m

Charleston

Sun 7/2

06:00-09:40

1 stop22h 40m

£809

Fastest return journey

ManchesterColumbia

MAN Manchester - CAE Columbia Metropolitan

MANCAE

Manchester

Wed 13/1

12:40-22:25

1 stop14h 45m

Columbia Metropolitan

Tue 2/2

12:00-10:30

1 stop17h 30m

£815

ManchesterGreenville

MAN Manchester - GSP Greenville

MANGSP

Manchester

Mon 7/12

09:45-10:29

2 stops29h 44m

Greenville

Mon 14/12

16:06-16:30

2 stops19h 24m

£816

ManchesterCharleston

MAN Manchester - CHS Charleston

MANCHS

Manchester

Mon 23/11

11:55-23:52

2 stops16h 57m

Charleston

Mon 30/11

11:32-11:45

2 stops19h 13m

£831

ManchesterColumbia

MAN Manchester - CAE Columbia Metropolitan

MANCAE

Manchester

Wed 6/1

06:05-17:54

2 stops16h 49m

Columbia Metropolitan

Wed 27/1

17:15-14:55

2 stops16h 40m

£856

ManchesterGreenville

MAN Manchester - GSP Greenville

MANGSP

Manchester

Thu 19/11

14:55-11:07

1 stop25h 12m

Greenville

Thu 26/11

08:15-10:05

2 stops20h 50m

£878

ManchesterMyrtle Beach

MAN Manchester - MYR Myrtle Beach Intl

MANMYR

Manchester

Fri 6/11

14:55-15:01

1 stop29h 06m

Myrtle Beach Intl

Mon 9/11

11:30-16:05

2 stops23h 35m

£889

ManchesterColumbia

MAN Manchester - CAE Columbia Metropolitan

MANCAE

Manchester

Fri 4/12

11:55-23:58

2 stops17h 03m

Columbia Metropolitan

Fri 11/12

20:17-16:35

2 stops15h 18m

£901

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Manchester to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South Carolina?

The month of April is another great option to travel to South Carolina, with average flight prices from Manchester averaging around £751.

Can stopping save me money on Manchester to South Carolina flights?

You could potentially save up to 18% on your flight if you consider stops on a Manchester to South Carolina flight.

Cheap Manchester to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to South Carolina

Best price found	£412
Fastest flight time	15h 10m
Direct flights	None

The best one-way flight to South Carolina from Manchester in the past 72 hours is £412. The best return flight deal from Manchester to South Carolina found on momondo in the last 72 hours is £576.

The fastest flight from Manchester to South Carolina takes 15h 10m

There are no direct flights from Manchester to South Carolina. There are no popular flight routes from Manchester to South Carolina.

Search flight deals

Frequently asked questions about flying from Manchester to South Carolina

When did momondo last update prices for flights from Manchester Airport to South Carolina?
Prices for flights from Manchester Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Manchester Airport to South Carolina?
As of October 2026, there are 5 operators available to choose from for flights from Manchester Airport to South Carolina.
How old do you have to be to fly from Manchester Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Manchester to South Carolina

Compare and see reviews for airlines that fly from Manchester to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Virgin Atlantic	PriceFrom £595	Free Cancellation	Rating 7.5 697 reviews	Search Virgin Atlantic flights
American Airlines	PriceFrom £624	Free Cancellation	Rating 7.0 12,193 reviews	Search American Airlines flights
British Airways	PriceFrom £630	Free Cancellation	Rating 6.7 8,270 reviews	Search British Airways flights
Delta	PriceFrom £663	Free Cancellation	Rating 7.8 8,678 reviews	Search Delta flights
Aer Lingus	PriceFrom £822	Free Cancellation	Rating 7.3 1,854 reviews	Search Aer Lingus flights

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to South Carolina?

It is quick and easy to find Manchester to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Manchester to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Manchester with this policy.

How can momondo help me find flights from Manchester to South Carolina?

Once all potential Manchester to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Manchester to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.