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Cheap flights from Manchester to South Carolina from £277

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester to South Carolina departing on 10/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Manchester to South Carolina

Cheap return flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:55 - 23:59
MAN
-
CLT
17h 04m2 stops
Multiple Airlines Logo
06:00 - 10:45
CLT
-
MAN
23h 45m3 stops
£510Multiple Airlines
Tue, 3 Feb - Tue, 10 Feb
Multiple Airlines Logo
09:10 - 23:59
MAN
-
CLT
19h 49m2 stops
Multiple Airlines Logo
09:06 - 17:55
CLT
-
MAN
27h 49m2 stops
£531Multiple Airlines
Mon, 2 Feb - Mon, 9 Feb
Virgin Atlantic Logo
09:00 - 20:27
MAN
-
CAE
16h 27m1 stop
Virgin Atlantic Logo
18:59 - 16:05
CAE
-
MAN
16h 06m2 stops
£604Virgin Atlantic
Mon, 2 Feb - Mon, 9 Feb
Virgin Atlantic Logo
05:50 - 16:18
MAN
-
CAE
15h 28m2 stops
Virgin Atlantic Logo
18:59 - 16:05
CAE
-
MAN
16h 06m2 stops
£605Virgin Atlantic
Mon, 2 Feb - Mon, 9 Feb
Scandinavian Airlines Logo
21:40 - 22:29
MAN
-
CLT
29h 49m2 stops
Scandinavian Airlines Logo
16:30 - 08:55
CLT
-
MAN
35h 25m2 stops
£605Scandinavian Airlines
Sun, 5 Apr - Sun, 19 Apr
British Airways Logo
06:15 - 23:58
MAN
-
SAV
22h 43m2 stops
British Airways Logo
11:33 - 11:25
SAV
-
MAN
18h 52m2 stops
£606British Airways
Tue, 3 Feb - Tue, 10 Feb
Scandinavian Airlines Logo
09:35 - 23:57
MAN
-
CLT
19h 22m2 stops
Scandinavian Airlines Logo
10:00 - 08:55
CLT
-
MAN
41h 55m2 stops
£614Scandinavian Airlines
Thu, 14 May - Thu, 4 Jun
British Airways Logo
08:00 - 22:42
MAN
-
CHS
19h 42m2 stops
British Airways Logo
11:17 - 09:45
CHS
-
MAN
17h 28m2 stops
£619British Airways
Wed, 29 Apr - Thu, 14 May
Delta Logo
13:30 - 23:58
MAN
-
SAV
15h 28m1 stop
Delta Logo
14:53 - 10:10
SAV
-
MAN
14h 17m2 stops
£626Delta
Tue, 3 Feb - Tue, 10 Feb
Delta Logo
14:50 - 11:24
MAN
-
CHS
25h 34m2 stops
Delta Logo
17:25 - 08:25
CHS
-
MAN
10h 00m1 stop
£641Delta
Wed, 29 Apr - Thu, 14 May

Scandinavian Airlines flights from Manchester to South Carolina

Our best Scandinavian Airlines deals on Manchester to South Carolina flight tickets
Scandinavian Airlines
5 Apr
MAN21:40Manchester
29h 49m
2 stops
CLT22:29Charlotte Douglas
19 Apr
CLT16:30Charlotte Douglas
35h 25m
2 stops
MAN08:55Manchester
£605
Find similar
Scandinavian Airlines
14 May
MAN09:35Manchester
19h 22m
2 stops
CLT23:57Charlotte Douglas
4 Jun
CLT10:00Charlotte Douglas
41h 55m
2 stops
MAN08:55Manchester
£614
Find similar
Scandinavian Airlines
26 Feb
MAN19:15Manchester
31h 42m
2 stops
CLT21:57Charlotte Douglas
19 Mar
CLT10:15Charlotte Douglas
19h 15m
2 stops
MAN09:30Manchester
£619
Find similar

Lufthansa flights from Manchester to South Carolina

Our best Lufthansa deals on Manchester to South Carolina flight tickets
Lufthansa
17 Jan
MAN06:45Manchester
15h 10m
1 stop
CLT16:55Charlotte Douglas
24 Jan
CLT18:50Charlotte Douglas
23h 30m
1 stop
MAN23:20Manchester
£700
Find similar
Lufthansa
26 Feb
MAN06:25Manchester
15h 30m
1 stop
CLT16:55Charlotte Douglas
19 Mar
CLT19:50Charlotte Douglas
23h 30m
1 stop
MAN23:20Manchester
£703
Find similar
Lufthansa
8 Jan
MAN06:00Manchester
22h 48m
2 stops
GSP23:48Greenville
17 Jan
GSP12:04Greenville
19h 06m
2 stops
MAN12:10Manchester
£732
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 21 December 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Tue 3/2

11:55-23:59

2 stops17h 04m

Charlotte Douglas

Tue 10/2

06:00-10:45

3 stops23h 45m

£510

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Mon 2/2

09:10-23:59

2 stops19h 49m

Charlotte Douglas

Mon 9/2

09:06-17:55

2 stops27h 49m

£531

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Mon 2/2

09:00-20:27

1 stop16h 27m

Columbia Metropolitan

Mon 9/2

18:59-16:05

2 stops16h 06m

£604

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Mon 2/2

05:50-16:18

2 stops15h 28m

Columbia Metropolitan

Mon 9/2

18:59-16:05

2 stops16h 06m

£605

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sun 5/4

21:40-22:29

2 stops29h 49m

Charlotte Douglas

Sun 19/4

16:30-08:55

2 stops35h 25m

£605

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Tue 3/2

06:15-23:58

2 stops22h 43m

Savannah/Hilton Head

Tue 10/2

11:33-11:25

2 stops18h 52m

£606

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Thu 14/5

09:35-23:57

2 stops19h 22m

Charlotte Douglas

Thu 4/6

10:00-08:55

2 stops41h 55m

£614

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 29/4

08:00-22:42

2 stops19h 42m

Charleston

Thu 14/5

11:17-09:45

2 stops17h 28m

£619

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Tue 3/2

13:30-23:58

1 stop15h 28m

Savannah/Hilton Head

Tue 10/2

14:53-10:10

2 stops14h 17m

£626

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 29/4

14:50-11:24

2 stops25h 34m

Charleston

Thu 14/5

17:25-08:25

1 stop10h 00m

£641

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Manchester to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The month of September is another great option to travel to South Carolina, with average flight prices from Manchester averaging around £633.

What is the cheapest day to depart on your flight to South Carolina?

The cheapest day to depart from Manchester to South Carolina is on a Wednesday when prices can be found for as low as £693. Flights from Manchester to South Carolina on a Saturday will generally be more expensive and average around £758. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to South Carolina?

In the evening is the cheapest time of day to fly from Manchester to South Carolina when you can find flight prices for as low as £703. Flying to South Carolina in the evening is an ideal time because this is during off-peak travel hours. Try not to purchase tickets in the afternoon because they tend to be around £866. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Manchester when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around £742 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Manchester for as low as £688 on momondo.

Can stopping save me money on Manchester to South Carolina flights?

You could potentially save up to 18% on your flight if you consider stops on a Manchester to South Carolina flight.

Cheap Manchester to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester to South Carolina

Fastest flight time

14h 50m

Direct flights

None
The fastest flight from Manchester to South Carolina takes 14h 50m
There are no direct flights from Manchester to South Carolina. There are no popular flight routes from Manchester to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Manchester Airport to South Carolina?

    Prices for flights from Manchester Airport to South Carolina refresh daily.

  • How many operators does momondo search for flights from Manchester Airport to South Carolina?

  • How old do you have to be to fly from Manchester Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Manchester to South Carolina

Compare and see reviews for airlines that fly from Manchester to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
FinnairPriceFrom £514Free CancellationRating
7.6
1,339 reviews
Search Finnair flights
British AirwaysPriceFrom £544Free CancellationRating
6.7
7,602 reviews
Search British Airways flights
Virgin AtlanticPriceFrom £568Free CancellationRating
7.5
675 reviews
Search Virgin Atlantic flights
KLMPriceFrom £581Free CancellationRating
7.7
1,431 reviews
Search KLM flights
DeltaPriceFrom £625Free CancellationRating
7.9
8,017 reviews
Search Delta flights
Aer LingusPriceFrom £803Free CancellationRating
7.2
1,408 reviews
Search Aer Lingus flights

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to South Carolina?

It is quick and easy to find Manchester to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Manchester to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Manchester with this policy.

How can momondo help me find flights from Manchester to South Carolina?

Once all potential Manchester to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Manchester to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organise and travel with friends or family. Trips is free – and available to use no matter where you book.
Start using Trips
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