Cheap flights from Southampton to South America from £688

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to South America departing on 30/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags
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Cheap return flights

Enter your travel dates to find the best prices.
Delta Logo
17:35 - 09:35
SOU
-
GRU
43h 00m2 stops
Delta Logo
23:45 - 08:50
GRU
-
SOU
30h 05m2 stops
£855Delta
Thu, 22 Jan - Sun, 15 Feb
Delta Logo
09:25 - 09:55
SOU
-
GRU
27h 30m2 stops
Delta Logo
21:00 - 08:50
GRU
-
SOU
56h 50m2 stops
£1,022Delta
Wed, 21 Jan - Fri, 13 Feb
Delta Logo
09:25 - 07:20
SOU
-
EZE
24h 55m2 stops
Delta Logo
20:55 - 17:05
EZE
-
SOU
41h 10m2 stops
£1,042Delta
Wed, 28 Jan - Wed, 4 Feb
Delta Logo
17:35 - 09:55
SOU
-
GRU
43h 20m2 stops
Delta Logo
21:00 - 08:50
GRU
-
SOU
56h 50m2 stops
£1,072Delta
Mon, 26 Jan - Fri, 13 Feb
Delta Logo
09:00 - 10:15
SOU
-
EZE
28h 15m2 stops
Delta Logo
20:55 - 08:45
EZE
-
SOU
32h 50m2 stops
£1,091Delta
Thu, 29 Jan - Thu, 5 Feb
KLM Logo
09:25 - 20:20
SOU
-
EZE
37h 55m2 stops
KLM Logo
16:25 - 08:25
EZE
-
SOU
37h 00m1 stop
£1,159KLM
Wed, 28 Jan - Wed, 4 Feb
KLM Logo
17:35 - 20:20
SOU
-
EZE
29h 45m2 stops
KLM Logo
16:25 - 08:45
EZE
-
SOU
37h 20m1 stop
£1,226KLM
Thu, 29 Jan - Thu, 5 Feb
Multiple Airlines Logo
14:15 - 15:10
SOU
-
EZE
27h 55m3 stops
Multiple Airlines Logo
02:25 - 19:20
EZE
-
SOU
37h 55m3 stops
£1,282Multiple Airlines
Thu, 29 Jan - Wed, 4 Feb
KLM Logo
09:25 - 07:15
SOU
-
EZE
24h 50m1 stop
KLM Logo
16:25 - 08:25
EZE
-
SOU
37h 00m1 stop
£1,311KLM
Wed, 28 Jan - Wed, 4 Feb
KLM Logo
17:35 - 07:15
SOU
-
EZE
16h 40m1 stop
KLM Logo
16:25 - 17:05
EZE
-
SOU
21h 40m1 stop
£1,367KLM
Thu, 29 Jan - Thu, 5 Feb

Delta flights from Southampton to South America

Our best Delta deals on Southampton to South America flight tickets
Delta
29 Jan
SOU09:00Southampton Eastleigh
28h 15m
2 stops
EZE10:15Buenos Aires Ministro Pistarini
5 Feb
EZE20:55Buenos Aires Ministro Pistarini
32h 50m
2 stops
SOU08:45Southampton Eastleigh
Delta
29 Jan
SOU09:00Southampton Eastleigh
25h 40m
2 stops
SCL07:40Santiago Arturo Merino Benitez
5 Feb
SCL23:10Santiago Arturo Merino Benitez
30h 35m
2 stops
SOU08:45Southampton Eastleigh
Delta
29 Dec
SOU18:05Southampton Eastleigh
38h 35m
2 stops
GRU05:40Sao Paulo Guarulhos Intl
11 Jan
GRU21:00Sao Paulo Guarulhos Intl
32h 50m
2 stops
SOU08:50Southampton Eastleigh

KLM flights from Southampton to South America

Our best KLM deals on Southampton to South America flight tickets
KLM
29 Jan
SOU17:35Southampton Eastleigh
29h 45m
2 stops
EZE20:20Buenos Aires Ministro Pistarini
5 Feb
EZE16:25Buenos Aires Ministro Pistarini
37h 20m
1 stop
SOU08:45Southampton Eastleigh
KLM
29 Jan
SOU17:35Southampton Eastleigh
16h 40m
1 stop
EZE07:15Buenos Aires Ministro Pistarini
5 Feb
EZE16:25Buenos Aires Ministro Pistarini
21h 40m
1 stop
SOU17:05Southampton Eastleigh

momondo Fare Finder

 
Customise your flight search to find flights from Southampton to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 17 December 2025.
Use the filters below to find and compare flights from Southampton to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Thu 22/1

17:35-09:35

2 stops43h 00m

Sao Paulo Guarulhos Intl

Sun 15/2

23:45-08:50

2 stops30h 05m

£855

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Wed 21/1

09:25-09:55

2 stops27h 30m

Sao Paulo Guarulhos Intl

Fri 13/2

21:00-08:50

2 stops56h 50m

£1,022

SouthamptonBuenos Aires

SOU - EZE

SOUEZE

Southampton Eastleigh

Wed 28/1

09:25-07:20

2 stops24h 55m

Buenos Aires Ministro Pistarini

Wed 4/2

20:55-17:05

2 stops41h 10m

£1,042

SouthamptonSao Paulo

SOU - GRU

SOUGRU

Southampton Eastleigh

Mon 26/1

17:35-09:55

2 stops43h 20m

Sao Paulo Guarulhos Intl

Fri 13/2

21:00-08:50

2 stops56h 50m

£1,072

SouthamptonBuenos Aires

SOU - EZE

SOUEZE

Southampton Eastleigh

Thu 29/1

09:00-10:15

2 stops28h 15m

Buenos Aires Ministro Pistarini

Thu 5/2

20:55-08:45

2 stops32h 50m

£1,091

SouthamptonBuenos Aires

SOU - EZE

SOUEZE

Southampton Eastleigh

Wed 28/1

09:25-20:20

2 stops37h 55m

Buenos Aires Ministro Pistarini

Wed 4/2

16:25-08:25

1 stop37h 00m

£1,159

SouthamptonBuenos Aires

SOU - EZE

SOUEZE

Southampton Eastleigh

Thu 29/1

17:35-20:20

2 stops29h 45m

Buenos Aires Ministro Pistarini

Thu 5/2

16:25-08:45

1 stop37h 20m

£1,226

SouthamptonBuenos Aires

SOU - EZE

SOUEZE

Southampton Eastleigh

Thu 29/1

14:15-15:10

3 stops27h 55m

Buenos Aires Ministro Pistarini

Wed 4/2

02:25-19:20

3 stops37h 55m

£1,282

SouthamptonBuenos Aires

SOU - EZE

SOUEZE

Southampton Eastleigh

Wed 28/1

09:25-07:15

1 stop24h 50m

Buenos Aires Ministro Pistarini

Wed 4/2

16:25-08:25

1 stop37h 00m

£1,311

SouthamptonBuenos Aires

SOU - EZE

SOUEZE

Southampton Eastleigh

Thu 29/1

17:35-07:15

1 stop16h 40m

Buenos Aires Ministro Pistarini

Thu 5/2

16:25-17:05

1 stop21h 40m

£1,367

Flights are sorted by cheapest return flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Southampton to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Southampton Eastleigh to South America?

Delta and KLM are the most popular carriers operating from Southampton Eastleigh to South America

Which airlines fly to South America?

British Airways, Avianca and LATAM Airlines are the top three most popular airlines that fly to South America from Southampton according to our data. British Airways is the first choice among our users, with 31% of people opting to fly with this airline when travelling to South America. Keep in mind that there are 18 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

Cheap Southampton to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to South America

Fastest flight time

14h 40m

Direct flights

None
The fastest flight from Southampton to South America takes 14h 40m
There are no direct flights from Southampton to South America. There are no popular flight routes from Southampton to South America.
  • When did momondo last update prices for flights from Southampton Eastleigh Airport to South America?

    Prices for flights from Southampton Eastleigh Airport to South America were last updated today.

  • How old do you have to be to fly from Southampton Eastleigh Airport to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Southampton Eastleigh Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to South America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Southampton to South America . Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Southampton to South America with flexible booking policies on momondo?

Flights from Southampton to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Southampton to South America?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South America from Southampton.

I’m not ready to book a flight from Southampton to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Southampton. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

We make it super easy to schedule, organise and travel with friends or family. Trips is free – and available to use no matter where you book.

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1 adult
Fri 16/1
Fri 23/1

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Popular Cities in South America

Popular flights according to clicks in the last 7 days on momondo