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Cheap flights from Knoxville to Manchester from £265

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 1/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags
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Find the cheapest flights from Knoxville to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
United Airlines Logo
07:00 - 10:20
TYS
-
MAN
23h 20m
2 stops
United Airlines Logo
11:30 - 17:02
MAN
-
TYS
34h 32m
2 stops
£672United Airlines
Tue, 27 Oct - Thu, 12 Nov
Delta Logo
16:37 - 10:30
TYS
-
MAN
13h 53m
1 stop
Delta Logo
13:30 - 21:45
MAN
-
TYS
13h 15m
1 stop
£678Delta
Tue, 27 Oct - Thu, 12 Nov
Delta Logo
12:06 - 06:40
TYS
-
MAN
14h 34m
2 stops
Delta Logo
13:30 - 20:40
MAN
-
TYS
12h 10m
1 stop
£681Delta
Tue, 27 Oct - Thu, 12 Nov
Multiple Airlines Logo
05:45 - 10:20
TYS
-
MAN
24h 35m
3 stops
Multiple Airlines Logo
11:30 - 09:50
MAN
-
TYS
27h 20m
2 stops
£693Multiple Airlines
Tue, 27 Oct - Thu, 12 Nov
Multiple Airlines Logo
19:20 - 07:15
TYS
-
MAN
31h 55m
2 stops
Multiple Airlines Logo
11:30 - 23:56
MAN
-
TYS
17h 26m
3 stops
£715Multiple Airlines
Tue, 27 Oct - Thu, 12 Nov
Air Canada Logo
05:45 - 10:20
TYS
-
MAN
24h 35m
3 stops
Air Canada Logo
11:30 - 23:56
MAN
-
TYS
17h 26m
3 stops
£717Air Canada
Tue, 27 Oct - Thu, 12 Nov
United Airlines Logo
13:00 - 10:25
TYS
-
MAN
16h 25m
2 stops
United Airlines Logo
09:00 - 16:58
MAN
-
TYS
36h 58m
2 stops
£726United Airlines
Tue, 11 Aug - Wed, 19 Aug
Delta Logo
14:14 - 07:15
TYS
-
MAN
12h 01m
1 stop
Delta Logo
13:00 - 22:00
MAN
-
TYS
14h 00m
1 stop
£732Delta
Sun, 9 Aug - Fri, 21 Aug
Lufthansa Logo
13:54 - 09:50
TYS
-
MAN
14h 56m
2 stops
Lufthansa Logo
07:00 - 23:59
MAN
-
TYS
21h 59m
2 stops
£734Lufthansa
Mon, 10 Aug - Thu, 20 Aug
Delta Logo
16:38 - 14:00
TYS
-
MAN
16h 22m
2 stops
Delta Logo
13:00 - 20:10
MAN
-
TYS
12h 10m
1 stop
£736Delta
Mon, 10 Aug - Thu, 20 Aug

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Lufthansa flights from Knoxville to Manchester

Our best Lufthansa deals on Knoxville to Manchester flight tickets
Lufthansa
10 Aug
TYS13:54Knoxville McGhee Tyson
14h 56m
2 stops
MAN09:50Manchester
20 Aug
MAN07:00Manchester
21h 59m
2 stops
TYS23:59Knoxville McGhee Tyson
£734
Lufthansa
16 Jul
TYS19:19Knoxville McGhee Tyson
22h 56m
2 stops
MAN23:15Manchester
26 Jul
MAN06:05Manchester
19h 29m
2 stops
TYS20:34Knoxville McGhee Tyson
£1,004

United Airlines flights from Knoxville to Manchester

Our best United Airlines deals on Knoxville to Manchester flight tickets
United Airlines
27 Oct
TYS07:00Knoxville McGhee Tyson
23h 20m
2 stops
MAN10:20Manchester
12 Nov
MAN11:30Manchester
34h 32m
2 stops
TYS17:02Knoxville McGhee Tyson
£672
United Airlines
11 Aug
TYS13:00Knoxville McGhee Tyson
16h 25m
2 stops
MAN10:25Manchester
19 Aug
MAN09:00Manchester
36h 58m
2 stops
TYS16:58Knoxville McGhee Tyson
£726
United Airlines
9 Aug
TYS10:00Knoxville McGhee Tyson
19h 25m
2 stops
MAN10:25Manchester
21 Aug
MAN06:05Manchester
19h 48m
2 stops
TYS20:53Knoxville McGhee Tyson
£744

momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 9 July 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

07:00-10:20

2 stops23h 20m

Manchester

Thu 12/11

11:30-17:02

2 stops34h 32m

£672

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

16:37-10:30

1 stop13h 53m

Manchester

Thu 12/11

13:30-21:45

1 stop13h 15m

£678

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

12:06-06:40

2 stops14h 34m

Manchester

Thu 12/11

13:30-20:40

1 stop12h 10m

£681

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

05:45-10:20

3 stops24h 35m

Manchester

Thu 12/11

11:30-09:50

2 stops27h 20m

£693

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

19:20-07:15

2 stops31h 55m

Manchester

Thu 12/11

11:30-23:56

3 stops17h 26m

£715

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

05:45-10:20

3 stops24h 35m

Manchester

Thu 12/11

11:30-23:56

3 stops17h 26m

£717

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 11/8

13:00-10:25

2 stops16h 25m

Manchester

Wed 19/8

09:00-16:58

2 stops36h 58m

£726
Fastest return journey

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sun 9/8

14:14-07:15

1 stop12h 01m

Manchester

Fri 21/8

13:00-22:00

1 stop14h 00m

£732

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 10/8

13:54-09:50

2 stops14h 56m

Manchester

Thu 20/8

07:00-23:59

2 stops21h 59m

£734

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 10/8

16:38-14:00

2 stops16h 22m

Manchester

Thu 20/8

13:00-20:10

1 stop12h 10m

£736

Flights are sorted by cheapest return flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Manchester?

What is the cheapest month to fly to Manchester?

In general, January is the cheapest month to fly from Knoxville to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £465. If you aren’t able to travel to Manchester during the month of January, then flying in March is also cheap. Prices for this month can be found on momondo for an average of £478.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Fastest flight time

15h 09m

Direct flights

None
The fastest flight from Knoxville to Manchester takes 15h 09m
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
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Frequently asked questions about flying from Knoxville to Manchester

  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 15h 09m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Harrogate
Southport
Derby
Lincoln
Ripon
Bradford
Shrewsbury
Skipton
Stoke-on-Trent
Preston
Morecambe
Aberystwyth
Kendal
Conwy

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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