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Cheap flights from Knoxville to Manchester from £587

This is the cheapest return flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 6/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Knoxville to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
United Airlines Logo
07:00 - 17:00TYS  Knoxville McGhee Tyson-MAN Manchester
29h 00m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
11:30 - 13:18MAN  Manchester-TYS Knoxville McGhee Tyson
30h 48m2 stops Toronto Pearson Intl Chicago O'Hare Intl
£587United Airlines
Sun, 6 Dec - Tue, 8 Dec
United Airlines Logo
14:00 - 17:00TYS  Knoxville McGhee Tyson-MAN Manchester
22h 00m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
11:30 - 13:18MAN  Manchester-TYS Knoxville McGhee Tyson
30h 48m2 stops Toronto Pearson Intl Chicago O'Hare Intl
£588United Airlines
Sun, 6 Dec - Tue, 8 Dec
United Airlines Logo
05:45 - 10:20TYS  Knoxville McGhee Tyson-MAN Manchester
23h 35m2 stops Washington, D.C. Dulles Intl Brussels Bruxelles-National
United Airlines Logo
06:10 - 20:54MAN  Manchester-TYS Knoxville McGhee Tyson
19h 44m2 stops Brussels Bruxelles-National Chicago O'Hare Intl
£598United Airlines
Mon, 2 Nov - Wed, 4 Nov
Delta Logo
14:40 - 08:45TYS  Knoxville McGhee Tyson-MAN Manchester
13h 05m1 stop Atlanta Hartsfield-Jackson
Delta Logo
05:50 - 23:46MAN  Manchester-TYS Knoxville McGhee Tyson
21h 56m2 stops Amsterdam Schiphol Atlanta Hartsfield-Jackson
£693Delta
Wed, 16 Dec - Wed, 17 Mar
Virgin Atlantic Logo
14:40 - 10:45TYS  Knoxville McGhee Tyson-MAN Manchester
15h 05m2 stops Atlanta Hartsfield-Jackson Orlando
Virgin Atlantic Logo
09:05 - 23:46MAN  Manchester-TYS Knoxville McGhee Tyson
18h 41m2 stops Amsterdam Schiphol Atlanta Hartsfield-Jackson
£695Virgin Atlantic
Wed, 16 Dec - Wed, 17 Mar
Delta Logo
12:34 - 08:45TYS  Knoxville McGhee Tyson-MAN Manchester
15h 11m1 stop Atlanta Hartsfield-Jackson
Delta Logo
12:40 - 09:12MAN  Manchester-TYS Knoxville McGhee Tyson
24h 32m1 stop Atlanta Hartsfield-Jackson
£713Delta
Wed, 16 Dec - Wed, 17 Mar
United Airlines Logo
18:20 - 08:15TYS  Knoxville McGhee Tyson-MAN Manchester
56h 55m2 stops Newark Toronto Pearson Intl
United Airlines Logo
06:10 - 16:59MAN  Manchester-TYS Knoxville McGhee Tyson
15h 49m2 stops Brussels Bruxelles-National Chicago O'Hare Intl
£727United Airlines
Fri, 6 Nov - Sat, 14 Nov
British Airways Logo
07:50 - 09:10TYS  Knoxville McGhee Tyson-MAN Manchester
20h 20m2 stops Philadelphia London Heathrow
British Airways Logo
17:35 - 18:46MAN  Manchester-TYS Knoxville McGhee Tyson
30h 11m2 stops London Heathrow Chicago O'Hare Intl
£733British Airways
Thu, 5 Nov - Sat, 14 Nov
British Airways Logo
07:50 - 09:10TYS  Knoxville McGhee Tyson-MAN Manchester
20h 20m2 stops Philadelphia London Heathrow
British Airways Logo
17:35 - 18:46MAN  Manchester-TYS Knoxville McGhee Tyson
30h 11m2 stops London Heathrow Chicago O'Hare Intl
£733British Airways
Thu, 5 Nov - Sat, 14 Nov
British Airways Logo
20:15 - 19:15TYS  Knoxville McGhee Tyson-MAN Manchester
18h 00m2 stops Chicago O'Hare Intl London Heathrow
British Airways Logo
20:15 - 22:50MAN  Manchester-TYS Knoxville McGhee Tyson
31h 35m2 stops London Heathrow Charlotte Douglas
£734British Airways
Mon, 14 Sep - Mon, 28 Sep

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Delta flights from Knoxville to Manchester

Our best Delta deals on Knoxville to Manchester flight tickets
Delta
16 Dec
TYS14:40Knoxville McGhee Tyson
13h 05m
1 stop
MAN08:45Manchester
17 Mar
MAN05:50Manchester
21h 56m
2 stops
TYS23:46Knoxville McGhee Tyson
£693
Delta
16 Dec
TYS12:34Knoxville McGhee Tyson
15h 11m
1 stop
MAN08:45Manchester
17 Mar
MAN12:40Manchester
24h 32m
1 stop
TYS09:12Knoxville McGhee Tyson
£713
Delta
6 Nov
TYS11:50Knoxville McGhee Tyson
17h 40m
1 stop
MAN10:30Manchester
14 Nov
MAN12:40Manchester
12h 29m
1 stop
TYS20:09Knoxville McGhee Tyson
£748

Virgin Atlantic flights from Knoxville to Manchester

Our best Virgin Atlantic deals on Knoxville to Manchester flight tickets
Virgin Atlantic
16 Dec
TYS14:40Knoxville McGhee Tyson
15h 05m
2 stops
MAN10:45Manchester
17 Mar
MAN09:05Manchester
18h 41m
2 stops
TYS23:46Knoxville McGhee Tyson
£695
Virgin Atlantic
19 Oct
TYS12:06Knoxville McGhee Tyson
15h 44m
1 stop
MAN08:50Manchester
14 Nov
MAN12:40Manchester
12h 29m
1 stop
TYS20:09Knoxville McGhee Tyson
£756
Virgin Atlantic
9 Aug
TYS14:14Knoxville McGhee Tyson
12h 01m
1 stop
MAN07:15Manchester
16 Aug
MAN11:15Manchester
17h 37m
1 stop
TYS23:52Knoxville McGhee Tyson
£998

momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 8 August 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Sun 6/12

07:00-17:00

2 stops29h 00m

Manchester

Tue 8/12

11:30-13:18

2 stops30h 48m

£587

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Sun 6/12

14:00-17:00

2 stops22h 00m

Manchester

Tue 8/12

11:30-13:18

2 stops30h 48m

£588

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 2/11

05:45-10:20

2 stops23h 35m

Manchester

Wed 4/11

06:10-20:54

2 stops19h 44m

£598

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Wed 16/12

14:40-08:45

1 stop13h 05m

Manchester

Wed 17/3

05:50-23:46

2 stops21h 56m

£693
Fastest return journey

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Wed 16/12

14:40-10:45

2 stops15h 05m

Manchester

Wed 17/3

09:05-23:46

2 stops18h 41m

£695

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Wed 16/12

12:34-08:45

1 stop15h 11m

Manchester

Wed 17/3

12:40-09:12

1 stop24h 32m

£713

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

18:20-08:15

2 stops56h 55m

Manchester

Sat 14/11

06:10-16:59

2 stops15h 49m

£727

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Thu 5/11

07:50-09:10

2 stops20h 20m

Manchester

Sat 14/11

17:35-18:46

2 stops30h 11m

£733

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Thu 5/11

07:50-09:10

2 stops20h 20m

Manchester

Sat 14/11

17:35-18:46

2 stops30h 11m

£733

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 14/9

20:15-19:15

2 stops18h 00m

Manchester

Mon 28/9

20:15-22:50

2 stops31h 35m

£734

Flights are sorted by cheapest return flights first.

Sorted by cheapest first

See travel insights to Manchester from

How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

In general, January is the cheapest month to fly from Knoxville to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £462. If you aren’t able to travel to Manchester during the month of January, then flying in March is also cheap. Prices for this month can be found on momondo for an average of £474.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Fastest flight time

15h 03m

Direct flights

None
The fastest flight from Knoxville to Manchester takes 15h 03m
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
Search flight deals

Frequently asked questions about flying from Knoxville to Manchester

  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 15h 03m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Harrogate
Southport
Derby
Lincoln
Ripon
Shrewsbury
Bradford
Stoke-on-Trent
Skipton
Preston
Morecambe
Kendal
Aberystwyth
Conwy

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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