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Cheap flights from Knoxville to Manchester from £286

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 16/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags
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Cheap return flights

Enter your travel dates to find the best prices.
Lufthansa Logo
19:20 - 23:20TYS-MAN
23h 00m2 stops
Lufthansa Logo
06:00 - 19:29MAN-TYS
18h 29m2 stops
£565Lufthansa
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Mon, 1 Dec - Thu, 4 Dec
United Airlines Logo
09:40 - 12:20TYS-MAN
22h 40m2 stops
United Airlines Logo
06:05 - 17:28MAN-TYS
16h 23m2 stops
£707United Airlines
Find Deal
Fri, 27 Mar - Tue, 31 Mar
Virgin Atlantic Logo
19:20 - 10:30TYS-MAN
11h 10m1 stop
Virgin Atlantic Logo
20:40 - 21:32MAN-TYS
29h 52m2 stops
£711Virgin Atlantic
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Fri, 27 Mar - Tue, 31 Mar
Delta Logo
19:20 - 10:30TYS-MAN
11h 10m1 stop
Delta Logo
11:00 - 23:44MAN-TYS
17h 44m1 stop
£720Delta
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Fri, 27 Mar - Tue, 31 Mar
Multiple Airlines Logo
20:07 - 16:05TYS-MAN
14h 58m2 stops
Multiple Airlines Logo
13:30 - 23:28MAN-TYS
14h 58m1 stop
£744Multiple Airlines
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Mon, 1 Dec - Thu, 4 Dec
United Airlines Logo
14:25 - 17:00TYS-MAN
21h 35m2 stops
United Airlines Logo
06:00 - 10:56MAN-TYS
33h 56m2 stops
£889United Airlines
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Mon, 1 Dec - Wed, 31 Dec
Delta Logo
08:35 - 08:20TYS-MAN
18h 45m2 stops
Delta Logo
13:30 - 10:31MAN-TYS
26h 01m1 stop
£896Delta
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Mon, 1 Dec - Wed, 31 Dec
Multiple Airlines Logo
11:29 - 07:00TYS-MAN
14h 31m1 stop
Multiple Airlines Logo
10:30 - 21:44MAN-TYS
16h 14m1 stop
£924Multiple Airlines
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Mon, 1 Dec - Thu, 4 Dec
Air Canada Logo
09:50 - 10:20TYS-MAN
19h 30m3 stops
Air Canada Logo
06:10 - 10:56MAN-TYS
33h 46m3 stops
£1,896Air Canada
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Mon, 1 Dec - Wed, 31 Dec
Air Canada Logo
09:50 - 10:20TYS-MAN
19h 30m3 stops
Air Canada Logo
06:10 - 10:56MAN-TYS
33h 46m3 stops
£2,445Air Canada
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Mon, 1 Dec - Wed, 31 Dec

United Airlines flights from Knoxville to Manchester

Our best United Airlines deals on Knoxville to Manchester flight tickets
United Airlines
27 Mar
TYS09:40Knoxville McGhee Tyson
22h 40m
2 stops
MAN12:20Manchester
31 Mar
MAN06:05Manchester
16h 23m
2 stops
TYS17:28Knoxville McGhee Tyson
£707
Find similar
United Airlines
1 Dec
TYS14:25Knoxville McGhee Tyson
21h 35m
2 stops
MAN17:00Manchester
31 Dec
MAN06:00Manchester
33h 56m
2 stops
TYS10:56Knoxville McGhee Tyson
£889
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Delta flights from Knoxville to Manchester

Our best Delta deals on Knoxville to Manchester flight tickets
Delta
27 Mar
TYS19:20Knoxville McGhee Tyson
11h 10m
1 stop
MAN10:30Manchester
31 Mar
MAN11:00Manchester
17h 44m
1 stop
TYS23:44Knoxville McGhee Tyson
£720
Find similar
Delta
1 Dec
TYS08:35Knoxville McGhee Tyson
18h 45m
2 stops
MAN08:20Manchester
31 Dec
MAN13:30Manchester
26h 01m
1 stop
TYS10:31Knoxville McGhee Tyson
£896
Find similar
Delta
25 Dec
TYS13:54Knoxville McGhee Tyson
15h 36m
1 stop
MAN10:30Manchester
1 Jan
MAN13:30Manchester
29h 00m
1 stop
TYS13:30Knoxville McGhee Tyson
£949
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momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 11 November 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/12

19:20-23:20

2 stops23h 00m

Manchester

Thu 4/12

06:00-19:29

2 stops18h 29m

£565

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 27/3

09:40-12:20

2 stops22h 40m

Manchester

Tue 31/3

06:05-17:28

2 stops16h 23m

£707

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 27/3

19:20-10:30

1 stop11h 10m

Manchester

Tue 31/3

20:40-21:32

2 stops29h 52m

£711

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 27/3

19:20-10:30

1 stop11h 10m

Manchester

Tue 31/3

11:00-23:44

1 stop17h 44m

£720

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/12

20:07-16:05

2 stops14h 58m

Manchester

Thu 4/12

13:30-23:28

1 stop14h 58m

£744

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/12

14:25-17:00

2 stops21h 35m

Manchester

Wed 31/12

06:00-10:56

2 stops33h 56m

£889

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/12

08:35-08:20

2 stops18h 45m

Manchester

Wed 31/12

13:30-10:31

1 stop26h 01m

£896

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/12

11:29-07:00

1 stop14h 31m

Manchester

Thu 4/12

10:30-21:44

1 stop16h 14m

£924

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/12

09:50-10:20

3 stops19h 30m

Manchester

Wed 31/12

06:10-10:56

3 stops33h 46m

£1,896

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 1/12

09:50-10:20

3 stops19h 30m

Manchester

Wed 31/12

06:10-10:56

3 stops33h 46m

£2,445

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Manchester?

The cheapest day to depart from Knoxville to Manchester is on a Monday. Travellers who choose to depart for Manchester on a Monday will often find tickets for as low as £783. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around £887. These prices are subject to change though, so be sure to set up a Price Alert for flights to Manchester.

What is the cheapest time of day to depart on your flight to Manchester?

The cheapest time of day to fly to Manchester is in the afternoon when flights can be purchased for as low as £930. Flights to Manchester are more costly at midday, with an average ticket price of £989. Departure times at midday fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Direct flights

None
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
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  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 11h 10m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Southport
Harrogate
Lincoln
Bradford
Derby
Morecambe
Aberystwyth
Skipton
Bolton
Preston
Stoke-on-Trent
Shrewsbury
Kendal
Ludlow

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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