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Cheap flights from Knoxville to Manchester from £171

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 17/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags
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Cheap return flights

Enter your travel dates to find the best prices.
British Airways Logo
16:02 - 16:20
TYS
-
MAN
19h 18m
2 stops
British Airways Logo
07:55 - 21:07
MAN
-
TYS
18h 12m
2 stops
£470British Airways
Wed, 25 Feb - Sun, 1 Mar
United Airlines Logo
06:45 - 08:45
TYS
-
MAN
21h 00m
2 stops
United Airlines Logo
06:10 - 10:49
MAN
-
TYS
33h 39m
2 stops
£485United Airlines
Thu, 26 Feb - Thu, 5 Mar
United Airlines Logo
14:21 - 14:50
TYS
-
MAN
19h 29m
2 stops
United Airlines Logo
06:00 - 20:47
MAN
-
TYS
18h 47m
3 stops
£807United Airlines
Sat, 7 Mar - Sun, 15 Mar
Delta Logo
17:00 - 10:30
TYS
-
MAN
12h 30m
1 stop
Delta Logo
11:05 - 10:31
MAN
-
TYS
27h 26m
2 stops
£962Delta
Sat, 7 Mar - Sun, 15 Mar
Aer Lingus Logo
11:26 - 07:40
TYS
-
MAN
15h 14m
2 stops
Aer Lingus Logo
20:55 - 18:11
MAN
-
TYS
26h 16m
2 stops
£1,156Aer Lingus
Tue, 26 May - Wed, 27 May
Aer Lingus Logo
11:26 - 07:40
TYS
-
MAN
15h 14m
2 stops
Aer Lingus Logo
20:55 - 18:11
MAN
-
TYS
26h 16m
2 stops
£1,156Aer Lingus
Tue, 26 May - Wed, 27 May
Ethiopian Air Logo
14:21 - 08:20
TYS
-
MAN
36h 59m
4 stops
Ethiopian Air Logo
18:30 - 15:15
MAN
-
TYS
49h 45m
4 stops
£2,316Ethiopian Air
Wed, 25 Feb - Sun, 1 Mar
Lufthansa Logo
19:20 - 17:05
TYS
-
MAN
16h 45m
2 stops
Lufthansa Logo
07:00 - 19:41
MAN
-
TYS
17h 41m
2 stops
£2,718Lufthansa
Wed, 6 May - Wed, 13 May
Lufthansa Logo
19:20 - 17:05
TYS
-
MAN
16h 45m
2 stops
Lufthansa Logo
07:00 - 19:41
MAN
-
TYS
17h 41m
2 stops
£2,719Lufthansa
Wed, 6 May - Wed, 13 May
Air Canada Logo
09:40 - 10:25
TYS
-
MAN
19h 45m
3 stops
Air Canada Logo
06:05 - 19:41
MAN
-
TYS
18h 36m
3 stops
£2,975Air Canada
Wed, 6 May - Wed, 13 May

Aer Lingus flights from Knoxville to Manchester

Our best Aer Lingus deals on Knoxville to Manchester flight tickets
Aer Lingus
26 May
TYS11:26Knoxville McGhee Tyson
15h 14m
2 stops
MAN07:40Manchester
27 May
MAN20:55Manchester
26h 16m
2 stops
TYS18:11Knoxville McGhee Tyson
£1,156
Aer Lingus
26 May
TYS11:26Knoxville McGhee Tyson
15h 14m
2 stops
MAN07:40Manchester
27 May
MAN20:55Manchester
26h 16m
2 stops
TYS18:11Knoxville McGhee Tyson
£1,156

Delta flights from Knoxville to Manchester

Our best Delta deals on Knoxville to Manchester flight tickets
Delta
7 Mar
TYS17:00Knoxville McGhee Tyson
12h 30m
1 stop
MAN10:30Manchester
15 Mar
MAN11:05Manchester
27h 26m
2 stops
TYS10:31Knoxville McGhee Tyson
£962
Delta
6 May
TYS10:04Knoxville McGhee Tyson
16h 11m
1 stop
MAN07:15Manchester
13 May
MAN10:40Manchester
17h 58m
1 stop
TYS23:38Knoxville McGhee Tyson
£3,843
Delta
6 May
TYS08:50Knoxville McGhee Tyson
17h 25m
1 stop
MAN07:15Manchester
13 May
MAN10:40Manchester
17h 58m
1 stop
TYS23:38Knoxville McGhee Tyson
£3,843

momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 14 January 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 25/2

16:02-16:20

2 stops19h 18m

Manchester

Sun 1/3

07:55-21:07

2 stops18h 12m

£470

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 26/2

06:45-08:45

2 stops21h 00m

Manchester

Thu 5/3

06:10-10:49

2 stops33h 39m

£485

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sat 7/3

14:21-14:50

2 stops19h 29m

Manchester

Sun 15/3

06:00-20:47

3 stops18h 47m

£807

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sat 7/3

17:00-10:30

1 stop12h 30m

Manchester

Sun 15/3

11:05-10:31

2 stops27h 26m

£962

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 26/5

11:26-07:40

2 stops15h 14m

Manchester

Wed 27/5

20:55-18:11

2 stops26h 16m

£1,156

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 26/5

11:26-07:40

2 stops15h 14m

Manchester

Wed 27/5

20:55-18:11

2 stops26h 16m

£1,156

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 25/2

14:21-08:20

4 stops36h 59m

Manchester

Sun 1/3

18:30-15:15

4 stops49h 45m

£2,316

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 6/5

19:20-17:05

2 stops16h 45m

Manchester

Wed 13/5

07:00-19:41

2 stops17h 41m

£2,718

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 6/5

19:20-17:05

2 stops16h 45m

Manchester

Wed 13/5

07:00-19:41

2 stops17h 41m

£2,719

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 6/5

09:40-10:25

3 stops19h 45m

Manchester

Wed 13/5

06:05-19:41

3 stops18h 36m

£2,975

Flights are sorted by cheapest return flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Manchester?

What is the cheapest month to fly to Manchester?

In general, January is the cheapest month to fly from Knoxville to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £462. If you aren’t able to travel to Manchester during the month of January, then flying in March is also cheap. Prices for this month can be found on momondo for an average of £475.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Fastest flight time

15h 14m

Direct flights

None
The fastest flight from Knoxville to Manchester takes 15h 14m
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
Search flight deals

  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 15h 14m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Southport
Leicester
Harrogate
Lincoln
Derby
Bradford
Aberystwyth
Morecambe
Bolton
Skipton
Preston
Shrewsbury
Stoke-on-Trent
Kendal
Ludlow

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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