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Cheap flights from Knoxville to Manchester from £587

This is the cheapest return flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 6/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Knoxville to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
United Airlines Logo
14:00 - 17:00TYS  Knoxville McGhee Tyson-MAN Manchester
22h 00m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
11:30 - 13:18MAN  Manchester-TYS Knoxville McGhee Tyson
30h 48m2 stops Toronto Pearson Intl Chicago O'Hare Intl
£587United Airlines
Sun, 6 Dec - Tue, 8 Dec
American Airlines Logo
15:53 - 09:50TYS  Knoxville McGhee Tyson-MAN Manchester
12h 57m2 stops Charlotte Douglas London Heathrow
American Airlines Logo
07:55 - 21:06MAN  Manchester-TYS Knoxville McGhee Tyson
18h 11m2 stops London Heathrow Charlotte Douglas
£733American Airlines
Wed, 16 Sep - Wed, 30 Sep
British Airways Logo
16:48 - 19:15TYS  Knoxville McGhee Tyson-MAN Manchester
21h 27m2 stops Chicago O'Hare Intl London Heathrow
British Airways Logo
20:15 - 20:01MAN  Manchester-TYS Knoxville McGhee Tyson
28h 46m2 stops London Heathrow Philadelphia
£734British Airways
Mon, 14 Sep - Mon, 28 Sep
Lufthansa Logo
19:20 - 23:15TYS  Knoxville McGhee Tyson-MAN Manchester
22h 55m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
Lufthansa Logo
17:55 - 23:59MAN  Manchester-TYS Knoxville McGhee Tyson
35h 04m2 stops Munich Franz Josef Strauss Washington, D.C. Dulles Intl
£736Lufthansa
Mon, 14 Sep - Mon, 28 Sep
Virgin Atlantic Logo
12:06 - 08:50TYS  Knoxville McGhee Tyson-MAN Manchester
15h 44m1 stop Atlanta Hartsfield-Jackson
Virgin Atlantic Logo
12:40 - 22:02MAN  Manchester-TYS Knoxville McGhee Tyson
14h 22m1 stop Atlanta Hartsfield-Jackson
£755Virgin Atlantic
Mon, 19 Oct - Sat, 7 Nov
Lufthansa Logo
19:25 - 23:15TYS  Knoxville McGhee Tyson-MAN Manchester
22h 50m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
Lufthansa Logo
06:00 - 20:54MAN  Manchester-TYS Knoxville McGhee Tyson
19h 54m2 stops Frankfurt am Main Chicago O'Hare Intl
£760Lufthansa
Mon, 19 Oct - Sat, 7 Nov
Virgin Atlantic Logo
12:06 - 08:50TYS  Knoxville McGhee Tyson-MAN Manchester
15h 44m1 stop Atlanta Hartsfield-Jackson
Virgin Atlantic Logo
05:50 - 19:49MAN  Manchester-TYS Knoxville McGhee Tyson
18h 59m2 stops Amsterdam Schiphol Detroit Metropolitan Wayne County
£761Virgin Atlantic
Mon, 19 Oct - Sat, 7 Nov
United Airlines Logo
19:25 - 10:25TYS  Knoxville McGhee Tyson-MAN Manchester
34h 00m2 stops Washington, D.C. Dulles Intl Brussels Bruxelles-National
United Airlines Logo
09:00 - 18:05MAN  Manchester-TYS Knoxville McGhee Tyson
38h 05m2 stops Toronto Pearson Intl Houston George Bush Intcntl
£763United Airlines
Sun, 27 Sep - Sun, 4 Oct
Delta Logo
08:55 - 08:50TYS  Knoxville McGhee Tyson-MAN Manchester
18h 55m1 stop Atlanta Hartsfield-Jackson
Delta Logo
13:00 - 20:15MAN  Manchester-TYS Knoxville McGhee Tyson
12h 15m1 stop Atlanta Hartsfield-Jackson
£763Delta
Mon, 14 Sep - Mon, 28 Sep
Air France Logo
18:13 - 14:00TYS  Knoxville McGhee Tyson-MAN Manchester
14h 47m2 stops Atlanta Hartsfield-Jackson Paris Charles de Gaulle
Air France Logo
13:00 - 20:15MAN  Manchester-TYS Knoxville McGhee Tyson
12h 15m1 stop Atlanta Hartsfield-Jackson
£767Air France
Mon, 14 Sep - Mon, 28 Sep

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Virgin Atlantic flights from Knoxville to Manchester

Our best Virgin Atlantic deals on Knoxville to Manchester flight tickets
Virgin Atlantic
19 Oct
TYS12:06Knoxville McGhee Tyson
15h 44m
1 stop
MAN08:50Manchester
7 Nov
MAN12:40Manchester
14h 22m
1 stop
TYS22:02Knoxville McGhee Tyson
£755
Virgin Atlantic
19 Oct
TYS12:06Knoxville McGhee Tyson
15h 44m
1 stop
MAN08:50Manchester
7 Nov
MAN05:50Manchester
18h 59m
2 stops
TYS19:49Knoxville McGhee Tyson
£761

Lufthansa flights from Knoxville to Manchester

Our best Lufthansa deals on Knoxville to Manchester flight tickets
Lufthansa
14 Sept
TYS19:20Knoxville McGhee Tyson
22h 55m
2 stops
MAN23:15Manchester
28 Sept
MAN17:55Manchester
35h 04m
2 stops
TYS23:59Knoxville McGhee Tyson
£736
Lufthansa
19 Oct
TYS19:25Knoxville McGhee Tyson
22h 50m
2 stops
MAN23:15Manchester
7 Nov
MAN06:00Manchester
19h 54m
2 stops
TYS20:54Knoxville McGhee Tyson
£760
Lufthansa
1 Sept
TYS13:00Knoxville McGhee Tyson
23h 05m
2 stops
MAN17:05Manchester
8 Sept
MAN07:00Manchester
21h 59m
2 stops
TYS23:59Knoxville McGhee Tyson
£789

momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 14 August 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

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Route

Depart

Return

Price

Cheapest return flight

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Sun 6/12

14:00-17:00

2 stops22h 00m

Manchester

Tue 8/12

11:30-13:18

2 stops30h 48m

£587

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Wed 16/9

15:53-09:50

2 stops12h 57m

Manchester

Wed 30/9

07:55-21:06

2 stops18h 11m

£733

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 14/9

16:48-19:15

2 stops21h 27m

Manchester

Mon 28/9

20:15-20:01

2 stops28h 46m

£734

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 14/9

19:20-23:15

2 stops22h 55m

Manchester

Mon 28/9

17:55-23:59

2 stops35h 04m

£736

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 19/10

12:06-08:50

1 stop15h 44m

Manchester

Sat 7/11

12:40-22:02

1 stop14h 22m

£755

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 19/10

19:25-23:15

2 stops22h 50m

Manchester

Sat 7/11

06:00-20:54

2 stops19h 54m

£760

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 19/10

12:06-08:50

1 stop15h 44m

Manchester

Sat 7/11

05:50-19:49

2 stops18h 59m

£761

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Sun 27/9

19:25-10:25

2 stops34h 00m

Manchester

Sun 4/10

09:00-18:05

2 stops38h 05m

£763

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 14/9

08:55-08:50

1 stop18h 55m

Manchester

Mon 28/9

13:00-20:15

1 stop12h 15m

£763
Fastest return journey

KnoxvilleManchester

TYS Knoxville McGhee Tyson - MAN Manchester

TYSMAN

Knoxville McGhee Tyson

Mon 14/9

18:13-14:00

2 stops14h 47m

Manchester

Mon 28/9

13:00-20:15

1 stop12h 15m

£767

Flights are sorted by cheapest return flights first.

Sorted by cheapest first

See travel insights to Manchester from

How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

In general, January is the cheapest month to fly from Knoxville to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £461. If you aren’t able to travel to Manchester during the month of January, then flying in March is also cheap. Prices for this month can be found on momondo for an average of £474.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Fastest flight time

15h 44m

Direct flights

None
The fastest flight from Knoxville to Manchester takes 15h 44m
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
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Frequently asked questions about flying from Knoxville to Manchester

  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 15h 44m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Harrogate
Southport
Derby
Lincoln
Ripon
Shrewsbury
Bradford
Skipton
Stoke-on-Trent
Preston
Morecambe
Kendal
Aberystwyth
Conwy

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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