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Cheap flights from Knoxville to Manchester from £301

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 29/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags
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Cheap return flights

American Airlines Logo
14:59 - 11:55TYS-MAN
15h 56m2 stops
American Airlines Logo
08:55 - 22:54MAN-TYS
18h 59m2 stops
£511American Airlines
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Fri, 7 Nov - Tue, 25 Nov
United Airlines Logo
19:20 - 17:00TYS-MAN
16h 40m2 stops
United Airlines Logo
06:00 - 17:08MAN-TYS
40h 08m2 stops
£512United Airlines
Find Deal
Mon, 3 Nov - Mon, 24 Nov
American Airlines Logo
17:00 - 14:00TYS-MAN
16h 00m2 stops
American Airlines Logo
10:50 - 23:06MAN-TYS
17h 16m2 stops
£524American Airlines
Find Deal
Mon, 26 Jan - Sat, 16 May
British Airways Logo
17:00 - 14:00TYS-MAN
16h 00m2 stops
British Airways Logo
07:00 - 20:39MAN-TYS
18h 39m2 stops
£532British Airways
Find Deal
Mon, 26 Jan - Sat, 16 May
Multiple Airlines Logo
18:16 - 18:30TYS-MAN
19h 14m2 stops
Multiple Airlines Logo
18:20 - 20:34MAN-TYS
31h 14m2 stops
£534Multiple Airlines
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Fri, 7 Nov - Mon, 24 Nov
Lufthansa Logo
19:26 - 17:00TYS-MAN
16h 34m2 stops
Lufthansa Logo
10:40 - 23:52MAN-TYS
18h 12m2 stops
£597Lufthansa
Find Deal
Fri, 10 Oct - Sat, 25 Oct
Multiple Airlines Logo
07:20 - 16:15TYS-MAN
27h 55m2 stops
Multiple Airlines Logo
10:30 - 22:52MAN-TYS
17h 22m1 stop
£610Multiple Airlines
Find Deal
Fri, 7 Nov - Mon, 24 Nov
Delta Logo
11:30 - 10:10TYS-MAN
17h 40m2 stops
Delta Logo
11:00 - 09:11MAN-TYS
27h 11m1 stop
£624Delta
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Mon, 26 Jan - Sat, 16 May
Delta Logo
12:47 - 08:20TYS-MAN
14h 33m2 stops
Delta Logo
09:05 - 10:45MAN-TYS
29h 40m1 stop
£668Delta
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Fri, 24 Oct - Sun, 26 Oct
Lufthansa Logo
19:20 - 12:20TYS-MAN
36h 00m2 stops
Lufthansa Logo
06:25 - 20:20MAN-TYS
18h 55m2 stops
£2,582Lufthansa
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Mon, 3 Nov - Mon, 24 Nov

Delta flights from Knoxville to Manchester

Our best Delta deals on Knoxville to Manchester flight tickets
Delta
26 Jan
TYS11:30Knoxville McGhee Tyson
17h 40m
2 stops
MAN10:10Manchester
16 May
MAN11:00Manchester
27h 11m
1 stop
TYS09:11Knoxville McGhee Tyson
£624
Find similar
Delta
24 Oct
TYS12:47Knoxville McGhee Tyson
14h 33m
2 stops
MAN08:20Manchester
26 Oct
MAN09:05Manchester
29h 40m
1 stop
TYS10:45Knoxville McGhee Tyson
£668
Find similar
Delta
24 Oct
TYS08:15Knoxville McGhee Tyson
19h 20m
1 stop
MAN08:35Manchester
26 Oct
MAN09:05Manchester
29h 40m
1 stop
TYS10:45Knoxville McGhee Tyson
£674
Find similar

Air Canada flights from Knoxville to Manchester

Our best Air Canada deals on Knoxville to Manchester flight tickets
Air Canada
26 Jan
TYS09:30Knoxville McGhee Tyson
19h 50m
3 stops
MAN10:20Manchester
16 May
MAN06:05Manchester
18h 12m
3 stops
TYS19:17Knoxville McGhee Tyson
£662
Find similar
Air Canada
7 Nov
TYS09:50Knoxville McGhee Tyson
19h 30m
3 stops
MAN10:20Manchester
24 Nov
MAN06:10Manchester
19h 10m
3 stops
TYS20:20Knoxville McGhee Tyson
£707
Find similar
Air Canada
3 Nov
TYS09:50Knoxville McGhee Tyson
19h 30m
3 stops
MAN10:20Manchester
24 Nov
MAN06:10Manchester
19h 10m
3 stops
TYS20:20Knoxville McGhee Tyson
£836
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 17 September 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 7/11

14:59-11:55

2 stops15h 56m

Manchester

Tue 25/11

08:55-22:54

2 stops18h 59m

£511

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 3/11

19:20-17:00

2 stops16h 40m

Manchester

Mon 24/11

06:00-17:08

2 stops40h 08m

£512

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 26/1

17:00-14:00

2 stops16h 00m

Manchester

Sat 16/5

10:50-23:06

2 stops17h 16m

£524

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 26/1

17:00-14:00

2 stops16h 00m

Manchester

Sat 16/5

07:00-20:39

2 stops18h 39m

£532

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 7/11

18:16-18:30

2 stops19h 14m

Manchester

Mon 24/11

18:20-20:34

2 stops31h 14m

£534

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 10/10

19:26-17:00

2 stops16h 34m

Manchester

Sat 25/10

10:40-23:52

2 stops18h 12m

£597

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 7/11

07:20-16:15

2 stops27h 55m

Manchester

Mon 24/11

10:30-22:52

1 stop17h 22m

£610

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 26/1

11:30-10:10

2 stops17h 40m

Manchester

Sat 16/5

11:00-09:11

1 stop27h 11m

£624

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 24/10

12:47-08:20

2 stops14h 33m

Manchester

Sun 26/10

09:05-10:45

1 stop29h 40m

£668

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 3/11

19:20-12:20

2 stops36h 00m

Manchester

Mon 24/11

06:25-20:20

2 stops18h 55m

£2,582

Flights are sorted by cheapest return flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Manchester?

What is the cheapest day to depart on your flight to Manchester?

The cheapest day to depart from Knoxville to Manchester is on a Monday. Travellers who choose to depart for Manchester on a Monday will often find tickets for as low as £756. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around £857. These prices are subject to change though, so be sure to set up a Price Alert for flights to Manchester.

What is the cheapest time of day to depart on your flight to Manchester?

The cheapest time of day to fly to Manchester is in the afternoon when flights can be purchased for as low as £898. Flights to Manchester are more costly at midday, with an average ticket price of £955. Departure times at midday fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Direct flights

None
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
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  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 10h 19m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Southport
Harrogate
Lincoln
Bradford
Derby
Aberystwyth
Morecambe
Bolton
Skipton
Stoke-on-Trent
Preston
Shrewsbury
Kendal
Conwy

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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