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Cheap flights from Knoxville to Manchester from £270

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 16/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags
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Find the cheapest flights from Knoxville to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
United Airlines Logo
08:26 - 10:20
TYS
-
MAN
20h 54m
2 stops
United Airlines Logo
06:10 - 19:17
MAN
-
TYS
18h 07m
2 stops
£601United Airlines
Mon, 9 Nov - Wed, 11 Nov
United Airlines Logo
14:20 - 10:20
TYS
-
MAN
15h 00m
2 stops
United Airlines Logo
11:30 - 13:18
MAN
-
TYS
30h 48m
2 stops
£745United Airlines
Fri, 6 Nov - Sat, 14 Nov
United Airlines Logo
14:20 - 10:20
TYS
-
MAN
15h 00m
2 stops
United Airlines Logo
11:30 - 13:18
MAN
-
TYS
30h 48m
2 stops
£746United Airlines
Fri, 6 Nov - Sat, 14 Nov
Virgin Atlantic Logo
19:20 - 10:30
TYS
-
MAN
10h 10m
1 stop
Virgin Atlantic Logo
13:25 - 23:46
MAN
-
TYS
15h 21m
1 stop
£750Virgin Atlantic
Thu, 5 Nov - Sat, 14 Nov
Delta Logo
08:47 - 10:30
TYS
-
MAN
20h 43m
1 stop
Delta Logo
13:25 - 23:46
MAN
-
TYS
15h 21m
1 stop
£751Delta
Fri, 6 Nov - Sat, 14 Nov
Delta Logo
11:30 - 10:10
TYS
-
MAN
17h 40m
2 stops
Delta Logo
13:25 - 23:46
MAN
-
TYS
15h 21m
1 stop
£754Delta
Thu, 5 Nov - Sat, 14 Nov
American Airlines Logo
16:15 - 11:55
TYS
-
MAN
14h 40m
2 stops
American Airlines Logo
09:50 - 22:54
MAN
-
TYS
18h 04m
2 stops
£756American Airlines
Fri, 6 Nov - Sat, 14 Nov
American Airlines Logo
17:51 - 14:50
TYS
-
MAN
15h 59m
2 stops
American Airlines Logo
08:50 - 22:54
MAN
-
TYS
19h 04m
2 stops
£756American Airlines
Fri, 6 Nov - Sat, 14 Nov
Delta Logo
17:57 - 16:35
TYS
-
MAN
17h 38m
2 stops
Delta Logo
13:25 - 23:46
MAN
-
TYS
15h 21m
1 stop
£757Delta
Fri, 6 Nov - Sat, 14 Nov
Air Canada Logo
10:16 - 10:20
TYS
-
MAN
19h 04m
3 stops
Air Canada Logo
11:30 - 14:42
MAN
-
TYS
32h 12m
3 stops
£765Air Canada
Thu, 5 Nov - Sat, 14 Nov

American Airlines flights from Knoxville to Manchester

Our best American Airlines deals on Knoxville to Manchester flight tickets
American Airlines
6 Nov
TYS17:51Knoxville McGhee Tyson
15h 59m
2 stops
MAN14:50Manchester
14 Nov
MAN08:50Manchester
17h 14m
2 stops
TYS21:04Knoxville McGhee Tyson
£756
American Airlines
6 Nov
TYS17:51Knoxville McGhee Tyson
15h 59m
2 stops
MAN14:50Manchester
14 Nov
MAN08:50Manchester
19h 04m
2 stops
TYS22:54Knoxville McGhee Tyson
£756

KLM flights from Knoxville to Manchester

Our best KLM deals on Knoxville to Manchester flight tickets
KLM
15 Jul
TYS18:36Knoxville McGhee Tyson
17h 09m
2 stops
MAN16:45Manchester
22 Jul
MAN12:10Manchester
16h 42m
2 stops
TYS23:52Knoxville McGhee Tyson
£806
KLM
19 Jun
TYS11:55Knoxville McGhee Tyson
15h 30m
2 stops
MAN08:25Manchester
29 Jun
MAN13:00Manchester
15h 54m
1 stop
TYS23:54Knoxville McGhee Tyson
£1,561
KLM
19 Jun
TYS11:55Knoxville McGhee Tyson
15h 30m
2 stops
MAN08:25Manchester
27 Jun
MAN13:15Manchester
15h 47m
1 stop
TYS00:02Knoxville McGhee Tyson
£1,660

momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 5 June 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 9/11

08:26-10:20

2 stops20h 54m

Manchester

Wed 11/11

06:10-19:17

2 stops18h 07m

£601

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

14:20-10:20

2 stops15h 00m

Manchester

Sat 14/11

11:30-13:18

2 stops30h 48m

£745

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

14:20-10:20

2 stops15h 00m

Manchester

Sat 14/11

11:30-13:18

2 stops30h 48m

£746
Fastest return journey

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 5/11

19:20-10:30

1 stop10h 10m

Manchester

Sat 14/11

13:25-23:46

1 stop15h 21m

£750

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

08:47-10:30

1 stop20h 43m

Manchester

Sat 14/11

13:25-23:46

1 stop15h 21m

£751

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 5/11

11:30-10:10

2 stops17h 40m

Manchester

Sat 14/11

13:25-23:46

1 stop15h 21m

£754

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

16:15-11:55

2 stops14h 40m

Manchester

Sat 14/11

09:50-22:54

2 stops18h 04m

£756

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

17:51-14:50

2 stops15h 59m

Manchester

Sat 14/11

08:50-22:54

2 stops19h 04m

£756

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

17:57-16:35

2 stops17h 38m

Manchester

Sat 14/11

13:25-23:46

1 stop15h 21m

£757

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 5/11

10:16-10:20

3 stops19h 04m

Manchester

Sat 14/11

11:30-14:42

3 stops32h 12m

£765

Flights are sorted by cheapest return flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Manchester?

What is the cheapest month to fly to Manchester?

In general, January is the cheapest month to fly from Knoxville to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £463. If you aren’t able to travel to Manchester during the month of January, then flying in March is also cheap. Prices for this month can be found on momondo for an average of £476.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Fastest flight time

15h 00m

Direct flights

None
The fastest flight from Knoxville to Manchester takes 15h 00m
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
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Frequently asked questions about flying from Knoxville to Manchester

  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 15h 00m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Southport
Harrogate
Derby
Lincoln
Ripon
Bradford
Shrewsbury
Morecambe
Preston
Aberystwyth
Skipton
Stoke-on-Trent
Kendal
Bolton

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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