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Cheap flights from Knoxville to Manchester from £308

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 28/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags
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Cheap return flights

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Lufthansa Logo
14:25 - 10:30TYS-MAN
15h 05m2 stops
Lufthansa Logo
07:00 - 20:22MAN-TYS
18h 22m2 stops
£525Lufthansa
Find Deal
Wed, 28 Jan - Tue, 1 Sep
Air Canada Logo
09:30 - 10:20TYS-MAN
19h 50m3 stops
Air Canada Logo
06:05 - 20:22MAN-TYS
19h 17m3 stops
£538Air Canada
Find Deal
Wed, 28 Jan - Tue, 1 Sep
Lufthansa Logo
14:25 - 10:30TYS-MAN
15h 05m2 stops
Lufthansa Logo
06:25 - 20:52MAN-TYS
19h 27m2 stops
£566Lufthansa
Find Deal
Mon, 12 Jan - Fri, 16 Jan
KLM Logo
13:00 - 08:20TYS-MAN
14h 20m2 stops
KLM Logo
13:25 - 18:52MAN-TYS
34h 27m1 stop
£581KLM
Find Deal
Mon, 12 Jan - Fri, 16 Jan
Virgin Atlantic Logo
17:00 - 10:30TYS-MAN
12h 30m1 stop
Virgin Atlantic Logo
11:00 - 21:46MAN-TYS
15h 46m1 stop
£583Virgin Atlantic
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Wed, 28 Jan - Tue, 1 Sep
Virgin Atlantic Logo
11:58 - 10:30TYS-MAN
17h 32m1 stop
Virgin Atlantic Logo
11:10 - 23:47MAN-TYS
17h 37m2 stops
£587Virgin Atlantic
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Wed, 28 Jan - Tue, 1 Sep
Lufthansa Logo
18:55 - 22:30TYS-MAN
47h 35m2 stops
Lufthansa Logo
17:40 - 20:47MAN-TYS
55h 07m2 stops
£601Lufthansa
Find Deal
Wed, 18 Mar - Sat, 21 Mar
Lufthansa Logo
19:25 - 17:00TYS-MAN
17h 35m2 stops
Lufthansa Logo
06:05 - 19:31MAN-TYS
18h 26m2 stops
£622Lufthansa
Find Deal
Fri, 27 Mar - Tue, 31 Mar
Scandinavian Airlines Logo
16:00 - 07:55TYS-MAN
35h 55m2 stops
Scandinavian Airlines Logo
09:35 - 23:44MAN-TYS
19h 09m2 stops
£656Scandinavian Airlines
Find Deal
Fri, 27 Mar - Tue, 31 Mar
Scandinavian Airlines Logo
16:00 - 07:55TYS-MAN
35h 55m2 stops
Scandinavian Airlines Logo
09:35 - 23:44MAN-TYS
19h 09m2 stops
£657Scandinavian Airlines
Find Deal
Fri, 27 Mar - Tue, 31 Mar

Lufthansa flights from Knoxville to Manchester

Our best Lufthansa deals on Knoxville to Manchester flight tickets
Lufthansa
28 Jan
TYS14:25Knoxville McGhee Tyson
15h 05m
2 stops
MAN10:30Manchester
1 Sept
MAN07:00Manchester
18h 22m
2 stops
TYS20:22Knoxville McGhee Tyson
£525
Find similar
Lufthansa
12 Jan
TYS14:25Knoxville McGhee Tyson
15h 05m
2 stops
MAN10:30Manchester
16 Jan
MAN06:25Manchester
19h 27m
2 stops
TYS20:52Knoxville McGhee Tyson
£566
Find similar
Lufthansa
18 Mar
TYS18:55Knoxville McGhee Tyson
47h 35m
2 stops
MAN22:30Manchester
21 Mar
MAN17:40Manchester
55h 07m
2 stops
TYS20:47Knoxville McGhee Tyson
£601
Find similar

Air Canada flights from Knoxville to Manchester

Our best Air Canada deals on Knoxville to Manchester flight tickets
Air Canada
28 Jan
TYS09:30Knoxville McGhee Tyson
19h 50m
3 stops
MAN10:20Manchester
1 Sept
MAN06:05Manchester
19h 17m
3 stops
TYS20:22Knoxville McGhee Tyson
£538
Find similar
Air Canada
12 Jan
TYS09:30Knoxville McGhee Tyson
19h 50m
3 stops
MAN10:20Manchester
16 Jan
MAN06:10Manchester
18h 17m
3 stops
TYS19:27Knoxville McGhee Tyson
£761
Find similar
Air Canada
3 Jan
TYS19:23Knoxville McGhee Tyson
33h 57m
3 stops
MAN10:20Manchester
10 Jan
MAN06:10Manchester
33h 47m
3 stops
TYS10:57Knoxville McGhee Tyson
£1,513
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 19 November 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 28/1

14:25-10:30

2 stops15h 05m

Manchester

Tue 1/9

07:00-20:22

2 stops18h 22m

£525

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 28/1

09:30-10:20

3 stops19h 50m

Manchester

Tue 1/9

06:05-20:22

3 stops19h 17m

£538

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

14:25-10:30

2 stops15h 05m

Manchester

Fri 16/1

06:25-20:52

2 stops19h 27m

£566

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

13:00-08:20

2 stops14h 20m

Manchester

Fri 16/1

13:25-18:52

1 stop34h 27m

£581

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 28/1

17:00-10:30

1 stop12h 30m

Manchester

Tue 1/9

11:00-21:46

1 stop15h 46m

£583

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 28/1

11:58-10:30

1 stop17h 32m

Manchester

Tue 1/9

11:10-23:47

2 stops17h 37m

£587

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 18/3

18:55-22:30

2 stops47h 35m

Manchester

Sat 21/3

17:40-20:47

2 stops55h 07m

£601

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 27/3

19:25-17:00

2 stops17h 35m

Manchester

Tue 31/3

06:05-19:31

2 stops18h 26m

£622

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 27/3

16:00-07:55

2 stops35h 55m

Manchester

Tue 31/3

09:35-23:44

2 stops19h 09m

£656

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 27/3

16:00-07:55

2 stops35h 55m

Manchester

Tue 31/3

09:35-23:44

2 stops19h 09m

£657

Flights are sorted by cheapest return flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Manchester?

The cheapest day to depart from Knoxville to Manchester is on a Monday. Travellers who choose to depart for Manchester on a Monday will often find tickets for as low as £784. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around £888. These prices are subject to change though, so be sure to set up a Price Alert for flights to Manchester.

What is the cheapest time of day to depart on your flight to Manchester?

The cheapest time of day to fly to Manchester is in the afternoon when flights can be purchased for as low as £931. Flights to Manchester are more costly at midday, with an average ticket price of £990. Departure times at midday fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Direct flights

None
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
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  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 11h 10m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Southport
Harrogate
Lincoln
Bradford
Derby
Morecambe
Aberystwyth
Skipton
Bolton
Preston
Stoke-on-Trent
Shrewsbury
Kendal
Ludlow

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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