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Cheap flights from Knoxville to Manchester from £388

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 6/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags
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Find the cheapest flights from Knoxville to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:16 - 10:20
TYS
-
MAN
19h 04m
2 stops
United Airlines Logo
06:10 - 16:49
MAN
-
TYS
15h 39m
2 stops
£608United Airlines
Mon, 7 Dec - Wed, 9 Dec
United Airlines Logo
10:16 - 10:20
TYS
-
MAN
19h 04m
2 stops
United Airlines Logo
06:10 - 16:49
MAN
-
TYS
15h 39m
2 stops
£609United Airlines
Mon, 7 Dec - Wed, 9 Dec
Delta Logo
15:55 - 10:30
TYS
-
MAN
14h 35m
1 stop
Delta Logo
13:30 - 21:45
MAN
-
TYS
13h 15m
1 stop
£686Delta
Tue, 27 Oct - Wed, 18 Nov
Delta Logo
11:30 - 06:40
TYS
-
MAN
15h 10m
2 stops
Delta Logo
13:30 - 23:46
MAN
-
TYS
15h 16m
1 stop
£689Delta
Tue, 27 Oct - Wed, 18 Nov
American Airlines Logo
20:37 - 16:30
TYS
-
MAN
15h 53m
2 stops
American Airlines Logo
07:50 - 19:33
MAN
-
TYS
16h 43m
2 stops
£691American Airlines
Tue, 27 Oct - Wed, 18 Nov
Multiple Airlines Logo
19:35 - 07:40
TYS
-
MAN
32h 05m
2 stops
Multiple Airlines Logo
06:10 - 23:37
MAN
-
TYS
22h 27m
3 stops
£700Multiple Airlines
Tue, 27 Oct - Wed, 18 Nov
Air Canada Logo
05:45 - 10:20
TYS
-
MAN
24h 35m
3 stops
Air Canada Logo
06:10 - 23:37
MAN
-
TYS
22h 27m
3 stops
£703Air Canada
Tue, 27 Oct - Wed, 18 Nov
United Airlines Logo
07:00 - 08:40
TYS
-
MAN
44h 40m
2 stops
United Airlines Logo
11:30 - 13:20
MAN
-
TYS
30h 50m
2 stops
£716United Airlines
Sat, 5 Dec - Sat, 12 Dec
Multiple Airlines Logo
19:35 - 08:40
TYS
-
MAN
32h 05m
2 stops
Multiple Airlines Logo
11:30 - 14:42
MAN
-
TYS
32h 12m
3 stops
£734Multiple Airlines
Sat, 5 Dec - Sat, 12 Dec
United Airlines Logo
14:00 - 10:20
TYS
-
MAN
15h 20m
2 stops
United Airlines Logo
11:30 - 17:02
MAN
-
TYS
34h 32m
2 stops
£754United Airlines
Fri, 6 Nov - Sat, 14 Nov

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Delta flights from Knoxville to Manchester

Our best Delta deals on Knoxville to Manchester flight tickets
Delta
27 Oct
TYS15:55Knoxville McGhee Tyson
14h 35m
1 stop
MAN10:30Manchester
18 Nov
MAN13:30Manchester
13h 15m
1 stop
TYS21:45Knoxville McGhee Tyson
£686
Delta
27 Oct
TYS11:30Knoxville McGhee Tyson
15h 10m
2 stops
MAN06:40Manchester
18 Nov
MAN13:30Manchester
15h 16m
1 stop
TYS23:46Knoxville McGhee Tyson
£689
Delta
27 Jul
TYS13:59Knoxville McGhee Tyson
13h 51m
1 stop
MAN08:50Manchester
12 Aug
MAN08:55Manchester
19h 59m
2 stops
TYS23:54Knoxville McGhee Tyson
£758

Air Canada flights from Knoxville to Manchester

Our best Air Canada deals on Knoxville to Manchester flight tickets
Air Canada
27 Oct
TYS05:45Knoxville McGhee Tyson
24h 35m
3 stops
MAN10:20Manchester
18 Nov
MAN06:10Manchester
22h 27m
3 stops
TYS23:37Knoxville McGhee Tyson
£703
Air Canada
29 Jul
TYS10:00Knoxville McGhee Tyson
19h 25m
3 stops
MAN10:25Manchester
11 Aug
MAN06:05Manchester
19h 19m
3 stops
TYS20:24Knoxville McGhee Tyson
£948
Air Canada
6 Nov
TYS09:45Knoxville McGhee Tyson
17h 55m
3 stops
MAN08:40Manchester
14 Nov
MAN11:30Manchester
32h 13m
3 stops
TYS14:43Knoxville McGhee Tyson
£1,011

momondo Fare Finder

 
Customise your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 23 June 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 7/12

10:16-10:20

2 stops19h 04m

Manchester

Wed 9/12

06:10-16:49

2 stops15h 39m

£608

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 7/12

10:16-10:20

2 stops19h 04m

Manchester

Wed 9/12

06:10-16:49

2 stops15h 39m

£609
Fastest return journey

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

15:55-10:30

1 stop14h 35m

Manchester

Wed 18/11

13:30-21:45

1 stop13h 15m

£686

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

11:30-06:40

2 stops15h 10m

Manchester

Wed 18/11

13:30-23:46

1 stop15h 16m

£689

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

20:37-16:30

2 stops15h 53m

Manchester

Wed 18/11

07:50-19:33

2 stops16h 43m

£691

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

19:35-07:40

2 stops32h 05m

Manchester

Wed 18/11

06:10-23:37

3 stops22h 27m

£700

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 27/10

05:45-10:20

3 stops24h 35m

Manchester

Wed 18/11

06:10-23:37

3 stops22h 27m

£703

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sat 5/12

07:00-08:40

2 stops44h 40m

Manchester

Sat 12/12

11:30-13:20

2 stops30h 50m

£716

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sat 5/12

19:35-08:40

2 stops32h 05m

Manchester

Sat 12/12

11:30-14:42

3 stops32h 12m

£734

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 6/11

14:00-10:20

2 stops15h 20m

Manchester

Sat 14/11

11:30-17:02

2 stops34h 32m

£754

Flights are sorted by cheapest return flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Manchester?

What is the cheapest month to fly to Manchester?

In general, January is the cheapest month to fly from Knoxville to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £470. If you aren’t able to travel to Manchester during the month of January, then flying in March is also cheap. Prices for this month can be found on momondo for an average of £483.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Fastest flight time

15h 09m

Direct flights

None
The fastest flight from Knoxville to Manchester takes 15h 09m
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
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Frequently asked questions about flying from Knoxville to Manchester

  • How far is Knoxville McGhee Tyson to Manchester by plane?

    A flight from Knoxville McGhee Tyson to Manchester will travel around 3949.9 mi. A reasonable flight in good conditions will take 15h 09m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The travel and health documents required for your trip to Manchester Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Manchester Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Harrogate
Southport
Derby
Lincoln
Ripon
Bradford
Shrewsbury
Skipton
Morecambe
Preston
Aberystwyth
Stoke-on-Trent
Kendal
Bolton

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

It is quick and easy to find Knoxville to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Manchester flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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