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Cheap flights from San Francisco to London from £410

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to London departing on 16/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap return flights

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Delta Logo
13:55 - 17:25SFO-SOU
19h 30m1 stop
Delta Logo
17:30 - 11:50SOU-SFO
26h 20m1 stop
£578Delta
Find Deal
Sun, 30 Nov - Tue, 9 Dec
Delta Logo
13:55 - 17:25SFO-SOU
19h 30m1 stop
Delta Logo
18:05 - 11:50SOU-SFO
25h 45m1 stop
£579Delta
Find Deal
Sun, 30 Nov - Mon, 15 Dec
Delta Logo
06:00 - 17:00SFO-SOU
27h 00m2 stops
Delta Logo
18:05 - 11:50SOU-SFO
25h 45m1 stop
£582Delta
Find Deal
Tue, 25 Nov - Mon, 8 Dec
Delta Logo
13:55 - 17:00SFO-SOU
19h 05m1 stop
Delta Logo
17:30 - 11:50SOU-SFO
26h 20m1 stop
£584Delta
Find Deal
Wed, 18 Feb - Wed, 4 Mar
Delta Logo
13:55 - 17:00SFO-SOU
19h 05m1 stop
Delta Logo
17:30 - 11:50SOU-SFO
26h 20m1 stop
£585Delta
Find Deal
Wed, 18 Feb - Mon, 23 Feb
Delta Logo
13:55 - 17:25SFO-SOU
19h 30m1 stop
Delta Logo
18:05 - 15:57SOU-SFO
29h 52m2 stops
£586Delta
Find Deal
Sun, 30 Nov - Mon, 8 Dec
Delta Logo
13:55 - 17:25SFO-SOU
19h 30m1 stop
Delta Logo
18:05 - 15:57SOU-SFO
29h 52m2 stops
£587Delta
Find Deal
Sun, 30 Nov - Mon, 15 Dec
Delta Logo
07:00 - 08:25SFO-SOU
17h 25m2 stops
Delta Logo
17:30 - 11:50SOU-SFO
26h 20m1 stop
£588Delta
Find Deal
Wed, 18 Feb - Wed, 4 Mar
KLM Logo
13:45 - 08:45SFO-SOU
35h 00m1 stop
KLM Logo
09:20 - 11:45SOU-SFO
34h 25m1 stop
£595KLM
Find Deal
Tue, 14 Apr - Thu, 23 Apr
KLM Logo
13:45 - 08:45SFO-SOU
35h 00m1 stop
KLM Logo
17:35 - 11:45SOU-SFO
26h 10m1 stop
£597KLM
Find Deal
Tue, 14 Apr - Thu, 30 Apr

KLM flights from San Francisco to Southampton

Our best KLM deals on San Francisco to Southampton flight tickets
KLM
14 Apr
SFO13:45San Francisco
35h 00m
1 stop
SOU08:45Southampton Eastleigh
23 Apr
SOU09:20Southampton Eastleigh
34h 25m
1 stop
SFO11:45San Francisco
£595
Find similar
KLM
14 Apr
SFO13:45San Francisco
35h 00m
1 stop
SOU08:45Southampton Eastleigh
30 Apr
SOU17:35Southampton Eastleigh
26h 10m
1 stop
SFO11:45San Francisco
£597
Find similar
KLM
14 Apr
SFO15:00San Francisco
18h 00m
2 stops
SOU17:00Southampton Eastleigh
23 Apr
SOU17:35Southampton Eastleigh
26h 10m
1 stop
SFO11:45San Francisco
£598
Find similar

Delta flights from San Francisco to Southampton

Our best Delta deals on San Francisco to Southampton flight tickets
Delta
30 Nov
SFO13:55San Francisco
19h 30m
1 stop
SOU17:25Southampton Eastleigh
9 Dec
SOU17:30Southampton Eastleigh
26h 20m
1 stop
SFO11:50San Francisco
£578
Find similar
Delta
30 Nov
SFO13:55San Francisco
19h 30m
1 stop
SOU17:25Southampton Eastleigh
15 Dec
SOU18:05Southampton Eastleigh
25h 45m
1 stop
SFO11:50San Francisco
£579
Find similar
Delta
25 Nov
SFO06:00San Francisco
27h 00m
2 stops
SOU17:00Southampton Eastleigh
8 Dec
SOU18:05Southampton Eastleigh
25h 45m
1 stop
SFO11:50San Francisco
£582
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from San Francisco to Southampton that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 7 November 2025.
Use the filters below to find and compare flights from San Francisco to Southampton that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Sun 30/11

13:55-17:25

1 stop19h 30m

Southampton Eastleigh

Tue 9/12

17:30-11:50

1 stop26h 20m

£578

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Sun 30/11

13:55-17:25

1 stop19h 30m

Southampton Eastleigh

Mon 15/12

18:05-11:50

1 stop25h 45m

£579

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Tue 25/11

06:00-17:00

2 stops27h 00m

Southampton Eastleigh

Mon 8/12

18:05-11:50

1 stop25h 45m

£582

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Wed 18/2

13:55-17:00

1 stop19h 05m

Southampton Eastleigh

Wed 4/3

17:30-11:50

1 stop26h 20m

£584

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Wed 18/2

13:55-17:00

1 stop19h 05m

Southampton Eastleigh

Mon 23/2

17:30-11:50

1 stop26h 20m

£585

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Sun 30/11

13:55-17:25

1 stop19h 30m

Southampton Eastleigh

Mon 8/12

18:05-15:57

2 stops29h 52m

£586

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Sun 30/11

13:55-17:25

1 stop19h 30m

Southampton Eastleigh

Mon 15/12

18:05-15:57

2 stops29h 52m

£587

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Wed 18/2

07:00-08:25

2 stops17h 25m

Southampton Eastleigh

Wed 4/3

17:30-11:50

1 stop26h 20m

£588

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Tue 14/4

13:45-08:45

1 stop35h 00m

Southampton Eastleigh

Thu 23/4

09:20-11:45

1 stop34h 25m

£595

San FranciscoSouthampton

SFO - SOU

SFOSOU

San Francisco

Tue 14/4

13:45-08:45

1 stop35h 00m

Southampton Eastleigh

Thu 30/4

17:35-11:45

1 stop26h 10m

£597

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to London from

How to get the cheapest flight ticket from San Francisco to Southampton

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from San Francisco to Southampton Eastleigh?

Delta and Aer Lingus are the most popular carriers operating from San Francisco to Southampton Eastleigh

Which airlines fly to Southampton?

United Airlines, Virgin Atlantic and British Airways are the top three most popular airlines that fly to Southampton from San Francisco according to our data. United Airlines is the first choice among our users, with 33% of people opting to fly with this airline when travelling to Southampton. Keep in mind that there are 7 different airlines that fly to Southampton on a routine basis, so you have a few additional options to choose from.

When to book flights from San Francisco to Southampton

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Southampton according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap San Francisco to Southampton (SFO to SOU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Southampton

Direct flights

None
There are no direct flights from San Francisco to Southampton. There are no popular flight routes from San Francisco to Southampton.
Search flight deals

  • How far is San Francisco to Southampton Eastleigh by plane?

    The straight-line distance from San Francisco to Southampton Eastleigh is 5341.1 mi. By plane, this route typically takes 17h 05m.

  • When did momondo last update prices for flights from San Francisco Airport to Southampton Eastleigh Airport?

    Prices for flights from San Francisco Airport to Southampton Eastleigh Airport were last updated today.

  • How old do you have to be to fly from San Francisco Airport to Southampton Eastleigh Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Southampton Eastleigh Airport.

  • What documentation or ID do you need to fly to Southampton Eastleigh Airport?

    The travel and health documents required for your trip to Southampton Eastleigh Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Southampton Eastleigh Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near London?

Book flights to London if you plan to visit one of these locations
Portsmouth

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Southampton?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Southampton for you.

Can I find flights from San Francisco to Southampton with flexible booking policies on momondo?

All flight searches from San Francisco to Southampton on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from San Francisco to Southampton?

momondo provides multiple filters to help you find the best flight to Southampton from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Southampton right now. Can momondo alert me if prices change?

Price alerts on flights to Southampton from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Southampton trip

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