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Cheap flights from South Carolina to Manchester from £280

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Manchester departing on 6/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from South Carolina to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:25 - 17:00MYR  Myrtle Beach Intl-MAN Manchester
24h 35m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
11:30 - 14:33MAN  Manchester-MYR Myrtle Beach Intl
32h 03m2 stops Toronto Pearson Intl Chicago O'Hare Intl
£586United Airlines
Tue, 8 Dec - Thu, 10 Dec
United Airlines Logo
11:25 - 17:00MYR  Myrtle Beach Intl-MAN Manchester
24h 35m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
11:30 - 14:33MAN  Manchester-MYR Myrtle Beach Intl
32h 03m2 stops Toronto Pearson Intl Chicago O'Hare Intl
£587United Airlines
Tue, 8 Dec - Thu, 10 Dec
United Airlines Logo
06:00 - 17:00CHS  Charleston-MAN Manchester
30h 00m2 stops Newark Frankfurt am Main
United Airlines Logo
11:30 - 15:24MAN  Manchester-CHS Charleston
32h 54m2 stops Toronto Pearson Intl Newark
£587United Airlines
Sun, 6 Dec - Tue, 8 Dec
United Airlines Logo
05:50 - 08:40GSP  Greenville-MAN Manchester
45h 50m2 stops Newark Toronto Pearson Intl
United Airlines Logo
06:10 - 22:59MAN  Manchester-GSP Greenville
21h 49m2 stops Brussels Bruxelles-National Chicago O'Hare Intl
£597United Airlines
Sun, 15 Nov - Wed, 18 Nov
United Airlines Logo
05:50 - 08:40GSP  Greenville-MAN Manchester
45h 50m2 stops Newark Toronto Pearson Intl
United Airlines Logo
06:10 - 23:47MAN  Manchester-GSP Greenville
22h 37m2 stops Brussels Bruxelles-National Newark
£597United Airlines
Sun, 15 Nov - Wed, 18 Nov
Multiple Airlines Logo
09:15 - 22:40CLT  Charlotte Douglas-MAN Manchester
32h 25m2 stops Toronto Pearson Intl Barcelona-El Prat
Multiple Airlines Logo
18:00 - 16:45MAN  Manchester-CLT Charlotte Douglas
27h 45m2 stops Barcelona-El Prat Munich Franz Josef Strauss
£635Multiple Airlines
Thu, 24 Sep - Wed, 30 Sep
Aer Lingus Logo
12:59 - 08:40CLT  Charlotte Douglas-MAN Manchester
14h 41m2 stops Toronto Pearson Intl Dublin
Aer Lingus Logo
11:40 - 21:30MAN  Manchester-CLT Charlotte Douglas
14h 50m2 stops Dublin Hartford Bradley Intl
£645Aer Lingus
Wed, 23 Sep - Thu, 8 Oct
Aer Lingus Logo
12:59 - 08:40CLT  Charlotte Douglas-MAN Manchester
14h 41m2 stops Toronto Pearson Intl Dublin
Aer Lingus Logo
08:10 - 15:05MAN  Manchester-CLT Charlotte Douglas
11h 55m1 stop Dublin
£655Aer Lingus
Wed, 23 Sep - Thu, 8 Oct
Virgin Atlantic Logo
10:40 - 08:15CLT  Charlotte Douglas-MAN Manchester
16h 35m1 stop New York John F Kennedy Intl
Virgin Atlantic Logo
20:50 - 16:11MAN  Manchester-CLT Charlotte Douglas
24h 21m2 stops Amsterdam Schiphol Atlanta Hartsfield-Jackson
£685Virgin Atlantic
Wed, 16 Sep - Mon, 21 Sep
Virgin Atlantic Logo
10:40 - 08:15CLT  Charlotte Douglas-MAN Manchester
16h 35m1 stop New York John F Kennedy Intl
Virgin Atlantic Logo
20:50 - 16:11MAN  Manchester-CLT Charlotte Douglas
24h 21m2 stops Amsterdam Schiphol Atlanta Hartsfield-Jackson
£685Virgin Atlantic
Wed, 16 Sep - Mon, 21 Sep

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Delta flights from South Carolina to Manchester

Our best Delta deals on South Carolina to Manchester flight tickets
Delta
3 Feb
SAV12:26Savannah/Hilton Head
15h 19m
1 stop
MAN08:45Manchester
10 Feb
MAN12:40Manchester
16h 19m
1 stop
SAV23:59Savannah/Hilton Head
£679
Delta
3 Feb
SAV11:45Savannah/Hilton Head
17h 20m
2 stops
MAN10:05Manchester
10 Feb
MAN12:40Manchester
13h 07m
1 stop
SAV20:47Savannah/Hilton Head
£683
Delta
24 Nov
SAV18:25Savannah/Hilton Head
11h 05m
1 stop
MAN10:30Manchester
1 Dec
MAN12:40Manchester
16h 18m
1 stop
SAV23:58Savannah/Hilton Head
£685

Air Canada flights from South Carolina to Manchester

Our best Air Canada deals on South Carolina to Manchester flight tickets
Air Canada
3 Feb
SAV09:45Savannah/Hilton Head
17h 55m
3 stops
MAN08:40Manchester
10 Feb
MAN06:10Manchester
22h 15m
3 stops
SAV23:25Savannah/Hilton Head
£694
Air Canada
3 Feb
SAV06:30Savannah/Hilton Head
21h 10m
3 stops
MAN08:40Manchester
10 Feb
MAN06:10Manchester
22h 15m
3 stops
SAV23:25Savannah/Hilton Head
£696
Air Canada
4 Nov
SAV09:50Savannah/Hilton Head
17h 25m
3 stops
MAN08:15Manchester
11 Nov
MAN06:10Manchester
22h 20m
3 stops
SAV23:30Savannah/Hilton Head
£732

momondo Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 10 August 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Myrtle BeachManchester

MYR Myrtle Beach Intl - MAN Manchester

MYRMAN

Myrtle Beach Intl

Tue 8/12

11:25-17:00

2 stops24h 35m

Manchester

Thu 10/12

11:30-14:33

2 stops32h 03m

£586

Myrtle BeachManchester

MYR Myrtle Beach Intl - MAN Manchester

MYRMAN

Myrtle Beach Intl

Tue 8/12

11:25-17:00

2 stops24h 35m

Manchester

Thu 10/12

11:30-14:33

2 stops32h 03m

£587

CharlestonManchester

CHS Charleston - MAN Manchester

CHSMAN

Charleston

Sun 6/12

06:00-17:00

2 stops30h 00m

Manchester

Tue 8/12

11:30-15:24

2 stops32h 54m

£587

GreenvilleManchester

GSP Greenville - MAN Manchester

GSPMAN

Greenville

Sun 15/11

05:50-08:40

2 stops45h 50m

Manchester

Wed 18/11

06:10-22:59

2 stops21h 49m

£597

GreenvilleManchester

GSP Greenville - MAN Manchester

GSPMAN

Greenville

Sun 15/11

05:50-08:40

2 stops45h 50m

Manchester

Wed 18/11

06:10-23:47

2 stops22h 37m

£597

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Thu 24/9

09:15-22:40

2 stops32h 25m

Manchester

Wed 30/9

18:00-16:45

2 stops27h 45m

£635

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 23/9

12:59-08:40

2 stops14h 41m

Manchester

Thu 8/10

11:40-21:30

2 stops14h 50m

£645
Fastest return journey

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 23/9

12:59-08:40

2 stops14h 41m

Manchester

Thu 8/10

08:10-15:05

1 stop11h 55m

£655

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 16/9

10:40-08:15

1 stop16h 35m

Manchester

Mon 21/9

20:50-16:11

2 stops24h 21m

£685

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 16/9

10:40-08:15

1 stop16h 35m

Manchester

Mon 21/9

20:50-16:11

2 stops24h 21m

£685

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from South Carolina to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

In general, April is the cheapest month to fly from South Carolina to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £438. If you aren’t able to travel to Manchester during the month of April, then flying in January is also cheap. Prices for this month can be found on momondo for an average of £496.

Can stopping save me money on South Carolina to Manchester flights?

You could potentially save up to 30% on your flight if you consider stops on a South Carolina to Manchester flight.

Cheap South Carolina to Manchester flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Manchester

Fastest flight time

10h 15m

Direct flights

None
The fastest flight from South Carolina to Manchester takes 10h 15m
There are no direct flights from South Carolina to Manchester. There are no popular flight routes from South Carolina to Manchester.
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Frequently asked questions about flying from South Carolina to Manchester

  • When did momondo last update prices for flights from South Carolina to Manchester Airport?

    Prices for flights from South Carolina to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Manchester Airport?

  • How old do you have to be to fly from South Carolina to Manchester Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Harrogate
Southport
Derby
Lincoln
Ripon
Shrewsbury
Bradford
Skipton
Stoke-on-Trent
Preston
Morecambe
Kendal
Aberystwyth
Conwy

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Manchester?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Manchester. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Manchester with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Manchester flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Manchester right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Manchester from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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