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Cheap flights from South Carolina to Manchester from £248

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Manchester departing on 20/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from South Carolina to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:25 - 17:00MYR  Myrtle Beach Intl-MAN Manchester
24h 35m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
11:30 - 14:33MAN  Manchester-MYR Myrtle Beach Intl
32h 03m2 stops Toronto Pearson Intl Chicago O'Hare Intl
£587United Airlines
Tue, 8 Dec - Thu, 10 Dec
United Airlines Logo
14:19 - 17:00GSP  Greenville-MAN Manchester
45h 41m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
06:10 - 23:19MAN  Manchester-GSP Greenville
22h 09m2 stops Brussels Bruxelles-National Newark
£621United Airlines
Sun, 29 Nov - Wed, 2 Dec
United Airlines Logo
14:19 - 17:00GSP  Greenville-MAN Manchester
45h 41m2 stops Chicago O'Hare Intl Frankfurt am Main
United Airlines Logo
06:10 - 23:19MAN  Manchester-GSP Greenville
22h 09m2 stops Brussels Bruxelles-National Newark
£622United Airlines
Sun, 29 Nov - Wed, 2 Dec
Lufthansa Logo
18:50 - 16:15CLT  Charlotte Douglas-MAN Manchester
16h 25m1 stop Munich Franz Josef Strauss
Lufthansa Logo
07:00 - 16:55MAN  Manchester-CLT Charlotte Douglas
14h 55m1 stop Munich Franz Josef Strauss
£623Lufthansa
Mon, 7 Dec - Fri, 18 Dec
Lufthansa Logo
19:47 - 16:15CLT  Charlotte Douglas-MAN Manchester
15h 28m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
Lufthansa Logo
07:00 - 16:55MAN  Manchester-CLT Charlotte Douglas
14h 55m1 stop Munich Franz Josef Strauss
£627Lufthansa
Mon, 7 Dec - Fri, 18 Dec
American Airlines Logo
20:15 - 14:55CLT  Charlotte Douglas-MAN Manchester
13h 40m1 stop London Heathrow
American Airlines Logo
08:55 - 16:05MAN  Manchester-CLT Charlotte Douglas
12h 10m1 stop London Heathrow
£634American Airlines
Wed, 4 Nov - Wed, 11 Nov
Multiple Airlines Logo
22:30 - 14:55CLT  Charlotte Douglas-MAN Manchester
11h 25m1 stop London Heathrow
Multiple Airlines Logo
09:55 - 10:08MAN  Manchester-CLT Charlotte Douglas
29h 13m2 stops Helsinki-Vantaa New York John F Kennedy Intl
£635Multiple Airlines
Wed, 4 Nov - Wed, 11 Nov
Delta Logo
10:40 - 09:40CLT  Charlotte Douglas-MAN Manchester
18h 00m1 stop New York John F Kennedy Intl
Delta Logo
14:55 - 09:58MAN  Manchester-CLT Charlotte Douglas
24h 03m1 stop New York John F Kennedy Intl
£640Delta
Tue, 3 Nov - Wed, 11 Nov
Virgin Atlantic Logo
10:40 - 08:20CLT  Charlotte Douglas-MAN Manchester
16h 40m1 stop New York John F Kennedy Intl
Virgin Atlantic Logo
15:00 - 22:44MAN  Manchester-CLT Charlotte Douglas
12h 44m1 stop New York John F Kennedy Intl
£682Virgin Atlantic
Tue, 15 Sep - Tue, 22 Sep
Virgin Atlantic Logo
18:25 - 10:30SAV  Savannah/Hilton Head-MAN Manchester
11h 05m1 stop Atlanta Hartsfield-Jackson
Virgin Atlantic Logo
12:40 - 21:15MAN  Manchester-SAV Savannah/Hilton Head
13h 35m1 stop Atlanta Hartsfield-Jackson
£687Virgin Atlantic
Tue, 24 Nov - Tue, 1 Dec

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Brussels Airlines flights from South Carolina to Manchester

Our best Brussels Airlines deals on South Carolina to Manchester flight tickets
Brussels Airlines
30 Sept
GSP14:51Greenville
25h 59m
3 stops
MAN21:50Manchester
27 Oct
MAN06:10Manchester
16h 51m
2 stops
GSP19:01Greenville
£931
Brussels Airlines
15 Dec
GSP14:54Greenville
14h 26m
2 stops
MAN10:20Manchester
5 Jan
MAN11:10Manchester
36h 40m
3 stops
GSP18:50Greenville
£1,179

United Airlines flights from South Carolina to Manchester

Our best United Airlines deals on South Carolina to Manchester flight tickets
United Airlines
8 Dec
MYR11:25Myrtle Beach Intl
24h 35m
2 stops
MAN17:00Manchester
10 Dec
MAN11:30Manchester
32h 03m
2 stops
MYR14:33Myrtle Beach Intl
£587
United Airlines
29 Nov
GSP14:19Greenville
45h 41m
2 stops
MAN17:00Manchester
2 Dec
MAN06:10Manchester
22h 09m
2 stops
GSP23:19Greenville
£621
United Airlines
29 Nov
GSP14:19Greenville
45h 41m
2 stops
MAN17:00Manchester
2 Dec
MAN06:10Manchester
22h 09m
2 stops
GSP23:19Greenville
£622

momondo Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 5 August 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Myrtle BeachManchester

MYR Myrtle Beach Intl - MAN Manchester

MYRMAN

Myrtle Beach Intl

Tue 8/12

11:25-17:00

2 stops24h 35m

Manchester

Thu 10/12

11:30-14:33

2 stops32h 03m

£587

GreenvilleManchester

GSP Greenville - MAN Manchester

GSPMAN

Greenville

Sun 29/11

14:19-17:00

2 stops45h 41m

Manchester

Wed 2/12

06:10-23:19

2 stops22h 09m

£621

GreenvilleManchester

GSP Greenville - MAN Manchester

GSPMAN

Greenville

Sun 29/11

14:19-17:00

2 stops45h 41m

Manchester

Wed 2/12

06:10-23:19

2 stops22h 09m

£622

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Mon 7/12

18:50-16:15

1 stop16h 25m

Manchester

Fri 18/12

07:00-16:55

1 stop14h 55m

£623

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Mon 7/12

19:47-16:15

2 stops15h 28m

Manchester

Fri 18/12

07:00-16:55

1 stop14h 55m

£627

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 4/11

20:15-14:55

1 stop13h 40m

Manchester

Wed 11/11

08:55-16:05

1 stop12h 10m

£634

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Wed 4/11

22:30-14:55

1 stop11h 25m

Manchester

Wed 11/11

09:55-10:08

2 stops29h 13m

£635

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Tue 3/11

10:40-09:40

1 stop18h 00m

Manchester

Wed 11/11

14:55-09:58

1 stop24h 03m

£640

CharlotteManchester

CLT Charlotte Douglas - MAN Manchester

CLTMAN

Charlotte Douglas

Tue 15/9

10:40-08:20

1 stop16h 40m

Manchester

Tue 22/9

15:00-22:44

1 stop12h 44m

£682
Fastest return journey

SavannahManchester

SAV Savannah/Hilton Head - MAN Manchester

SAVMAN

Savannah/Hilton Head

Tue 24/11

18:25-10:30

1 stop11h 05m

Manchester

Tue 1/12

12:40-21:15

1 stop13h 35m

£687

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from South Carolina to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

In general, April is the cheapest month to fly from South Carolina to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £439. If you aren’t able to travel to Manchester during the month of April, then flying in January is also cheap. Prices for this month can be found on momondo for an average of £498.

Can stopping save me money on South Carolina to Manchester flights?

You could potentially save up to 30% on your flight if you consider stops on a South Carolina to Manchester flight.

Cheap South Carolina to Manchester flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Manchester

Fastest flight time

9h 50m

Direct flights

None
The fastest flight from South Carolina to Manchester takes 9h 50m
There are no direct flights from South Carolina to Manchester. There are no popular flight routes from South Carolina to Manchester.
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Frequently asked questions about flying from South Carolina to Manchester

  • When did momondo last update prices for flights from South Carolina to Manchester Airport?

    Prices for flights from South Carolina to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Manchester Airport?

  • How old do you have to be to fly from South Carolina to Manchester Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Harrogate
Southport
Derby
Lincoln
Ripon
Shrewsbury
Bradford
Stoke-on-Trent
Skipton
Preston
Morecambe
Kendal
Aberystwyth
Conwy

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Manchester?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Manchester. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Manchester with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Manchester flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Manchester right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Manchester from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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