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Cheap flights from South Carolina to Manchester from £325

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Manchester departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
Lufthansa Logo
16:41 - 23:20
CHS
-
MAN
25h 39m2 stops
Lufthansa Logo
11:15 - 23:44
MAN
-
CHS
17h 29m2 stops
£455Lufthansa
Mon, 2 Feb - Wed, 25 Feb
British Airways Logo
11:33 - 15:15
SAV
-
MAN
22h 42m2 stops
British Airways Logo
17:20 - 23:58
MAN
-
SAV
35h 38m2 stops
£460British Airways
Fri, 23 Jan - Fri, 30 Jan
Delta Logo
08:40 - 10:30
SAV
-
MAN
20h 50m1 stop
Delta Logo
13:00 - 22:02
MAN
-
SAV
13h 02m1 stop
£465Delta
Wed, 4 Mar - Tue, 10 Mar
Delta Logo
14:01 - 10:30
SAV
-
MAN
15h 29m1 stop
Delta Logo
13:00 - 09:31
MAN
-
SAV
24h 31m2 stops
£469Delta
Wed, 4 Mar - Tue, 10 Mar
Multiple Airlines Logo
15:28 - 10:10
CHS
-
MAN
13h 42m2 stops
Multiple Airlines Logo
13:00 - 21:02
MAN
-
CHS
13h 02m1 stop
£469Multiple Airlines
Mon, 2 Feb - Wed, 25 Feb
American Airlines Logo
15:29 - 16:25
HHH
-
MAN
19h 56m2 stops
American Airlines Logo
06:15 - 12:20
MAN
-
HHH
35h 05m2 stops
£475American Airlines
Sat, 31 Jan - Sat, 7 Feb
American Airlines Logo
23:45 - 15:35
CLT
-
MAN
10h 50m1 stop
American Airlines Logo
08:10 - 16:00
MAN
-
CLT
12h 50m1 stop
£479American Airlines
Wed, 6 May - Thu, 14 May
United Airlines Logo
14:13 - 10:20
SAV
-
MAN
15h 07m2 stops
United Airlines Logo
06:10 - 21:36
MAN
-
SAV
20h 26m2 stops
£479United Airlines
Fri, 23 Jan - Tue, 27 Jan
United Airlines Logo
06:05 - 10:20
CHS
-
MAN
23h 15m2 stops
United Airlines Logo
06:10 - 20:02
MAN
-
CHS
18h 52m2 stops
£479United Airlines
Fri, 30 Jan - Tue, 3 Feb
Multiple Airlines Logo
13:11 - 09:50
CLT
-
MAN
15h 39m2 stops
Multiple Airlines Logo
19:40 - 16:00
MAN
-
CLT
25h 20m2 stops
£488Multiple Airlines
Wed, 6 May - Thu, 14 May

Lufthansa flights from South Carolina to Manchester

Our best Lufthansa deals on South Carolina to Manchester flight tickets
Lufthansa
2 Feb
CHS16:41Charleston
25h 39m
2 stops
MAN23:20Manchester
25 Feb
MAN11:15Manchester
17h 29m
2 stops
CHS23:44Charleston
£455
Find similar
Lufthansa
5 May
CLT18:40Charlotte Douglas
17h 25m
1 stop
MAN17:05Manchester
14 May
MAN07:00Manchester
14h 45m
1 stop
CLT16:45Charlotte Douglas
£463
Find similar
Lufthansa
5 May
CLT19:47Charlotte Douglas
16h 18m
2 stops
MAN17:05Manchester
14 May
MAN07:00Manchester
14h 45m
1 stop
CLT16:45Charlotte Douglas
£466
Find similar

British Airways flights from South Carolina to Manchester

Our best British Airways deals on South Carolina to Manchester flight tickets
British Airways
23 Jan
SAV11:33Savannah/Hilton Head
22h 42m
2 stops
MAN15:15Manchester
30 Jan
MAN17:20Manchester
35h 38m
2 stops
SAV23:58Savannah/Hilton Head
£460
Find similar
British Airways
4 Mar
SAV06:00Savannah/Hilton Head
23h 55m
2 stops
MAN10:55Manchester
10 Mar
MAN14:45Manchester
37h 13m
2 stops
SAV23:58Savannah/Hilton Head
£461
Find similar
British Airways
29 Apr
CLT17:05Charlotte Douglas
15h 05m
2 stops
MAN13:10Manchester
5 May
MAN08:40Manchester
18h 03m
2 stops
CLT21:43Charlotte Douglas
£480
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 18 December 2025.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Mon 2/2

16:41-23:20

2 stops25h 39m

Manchester

Wed 25/2

11:15-23:44

2 stops17h 29m

£455

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Fri 23/1

11:33-15:15

2 stops22h 42m

Manchester

Fri 30/1

17:20-23:58

2 stops35h 38m

£460

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 4/3

08:40-10:30

1 stop20h 50m

Manchester

Tue 10/3

13:00-22:02

1 stop13h 02m

£465

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 4/3

14:01-10:30

1 stop15h 29m

Manchester

Tue 10/3

13:00-09:31

2 stops24h 31m

£469

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Mon 2/2

15:28-10:10

2 stops13h 42m

Manchester

Wed 25/2

13:00-21:02

1 stop13h 02m

£469

Hilton Head IslandManchester

HHH - MAN

HHHMAN

Hilton Head Island

Sat 31/1

15:29-16:25

2 stops19h 56m

Manchester

Sat 7/2

06:15-12:20

2 stops35h 05m

£475

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

23:45-15:35

1 stop10h 50m

Manchester

Thu 14/5

08:10-16:00

1 stop12h 50m

£479

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Fri 23/1

14:13-10:20

2 stops15h 07m

Manchester

Tue 27/1

06:10-21:36

2 stops20h 26m

£479

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Fri 30/1

06:05-10:20

2 stops23h 15m

Manchester

Tue 3/2

06:10-20:02

2 stops18h 52m

£479

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

13:11-09:50

2 stops15h 39m

Manchester

Thu 14/5

19:40-16:00

2 stops25h 20m

£488

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Manchester from

How to get the cheapest flight ticket from South Carolina to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

In general, November is the cheapest month to fly from South Carolina to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £485. If you aren’t able to travel to Manchester during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of £485.

What is the cheapest day to depart on your flight to Manchester?

The cheapest day to depart from South Carolina to Manchester is on a Thursday. Travellers who choose to depart for Manchester on a Thursday will often find tickets for as low as £804. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around £1,091. These prices are subject to change though, so be sure to set up a Price Alert for flights to Manchester.

What is the cheapest time of day to depart on your flight to Manchester?

The cheapest time of day to fly to Manchester is at midday when flights can be purchased for as low as £804. Flights to Manchester are more costly in the afternoon, with an average ticket price of £961. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on South Carolina to Manchester flights?

You could potentially save up to 49% on your flight if you consider stops on a South Carolina to Manchester flight.

Cheap South Carolina to Manchester flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Manchester

Fastest flight time

13h 43m

Direct flights

None
The fastest flight from South Carolina to Manchester takes 13h 43m
There are no direct flights from South Carolina to Manchester. There are no popular flight routes from South Carolina to Manchester.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Manchester Airport?

    Prices for flights from South Carolina to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Manchester Airport?

  • How old do you have to be to fly from South Carolina to Manchester Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Manchester

Compare and see reviews for airlines that fly from South Carolina to Manchester with momondo
Airline
Rating
Free Cancellation
Price
Virgin AtlanticPriceFrom £480Free CancellationRating
7.5
675 reviews
Search Virgin Atlantic flights

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Southport
Leicester
Harrogate
Lincoln
Bradford
Derby
Aberystwyth
Morecambe
Bolton
Skipton
Preston
Shrewsbury
Stoke-on-Trent
Kendal
Ludlow

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Manchester?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Manchester. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Manchester with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Manchester flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Manchester right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Manchester from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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