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Cheap flights from South Carolina to Manchester from £221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Manchester departing on 24/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap return flights

Enter your travel dates to find the best prices.
Delta Logo
05:40 - 10:30GSP-MAN
23h 50m1 stop
Delta Logo
09:00 - 23:55MAN-GSP
19h 55m1 stop
£471Delta
Find Deal
Fri, 23 Jan - Mon, 2 Feb
Lufthansa Logo
11:49 - 23:20GSP-MAN
30h 31m2 stops
Lufthansa Logo
11:15 - 23:48MAN-GSP
17h 33m2 stops
£473Lufthansa
Find Deal
Thu, 15 Jan - Mon, 19 Jan
Lufthansa Logo
17:34 - 23:20GSP-MAN
24h 46m2 stops
Lufthansa Logo
06:25 - 23:48MAN-GSP
22h 23m2 stops
£473Lufthansa
Find Deal
Fri, 23 Jan - Mon, 2 Feb
United Airlines Logo
10:51 - 10:20GSP-MAN
18h 29m2 stops
United Airlines Logo
06:10 - 16:52MAN-GSP
15h 42m2 stops
£483United Airlines
Find Deal
Tue, 20 Jan - Mon, 2 Feb
British Airways Logo
11:00 - 09:10GSP-MAN
17h 10m2 stops
British Airways Logo
09:40 - 20:59MAN-GSP
16h 19m2 stops
£484British Airways
Find Deal
Thu, 22 Jan - Sun, 1 Feb
United Airlines Logo
10:20 - 09:50CLT-MAN
18h 30m2 stops
United Airlines Logo
07:00 - 16:45MAN-CLT
14h 45m1 stop
£496United Airlines
Find Deal
Wed, 29 Apr - Wed, 6 May
Multiple Airlines Logo
14:51 - 10:20CLT-MAN
15h 29m2 stops
Multiple Airlines Logo
18:45 - 17:55MAN-CLT
51h 10m2 stops
£499Multiple Airlines
Find Deal
Tue, 17 Mar - Sun, 22 Mar
American Airlines Logo
23:00 - 19:05CLT-MAN
15h 05m1 stop
American Airlines Logo
07:50 - 19:05MAN-CLT
16h 15m1 stop
£502American Airlines
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Thu, 26 Feb - Wed, 4 Mar
American Airlines Logo
18:30 - 11:00CLT-MAN
11h 30m1 stop
American Airlines Logo
09:50 - 19:05MAN-CLT
14h 15m1 stop
£503American Airlines
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Thu, 26 Feb - Wed, 4 Mar
Multiple Airlines Logo
11:10 - 10:20CHS-MAN
19h 10m3 stops
Multiple Airlines Logo
07:00 - 20:31MAN-CHS
42h 31m2 stops
£560Multiple Airlines
Find Deal
Tue, 24 Mar - Thu, 2 Apr

Virgin Atlantic flights from South Carolina to Manchester

Our best Virgin Atlantic deals on South Carolina to Manchester flight tickets
Virgin Atlantic
27 Mar
MYR10:55Myrtle Beach Intl
17h 00m
2 stops
MAN07:55Manchester
31 Mar
MAN11:00Manchester
11h 56m
1 stop
MYR17:56Myrtle Beach Intl
£603
Find similar
Virgin Atlantic
27 Mar
CHS14:25Charleston
13h 30m
2 stops
MAN07:55Manchester
31 Mar
MAN20:40Manchester
25h 09m
2 stops
CHS16:49Charleston
£609
Find similar
Virgin Atlantic
27 Mar
CHS14:25Charleston
13h 30m
2 stops
MAN07:55Manchester
31 Mar
MAN11:00Manchester
15h 20m
1 stop
CHS21:20Charleston
£625
Find similar

Delta flights from South Carolina to Manchester

Our best Delta deals on South Carolina to Manchester flight tickets
Delta
23 Jan
GSP05:40Greenville
23h 50m
1 stop
MAN10:30Manchester
2 Feb
MAN09:00Manchester
19h 55m
1 stop
GSP23:55Greenville
£471
Find similar
Delta
24 Jan
GSP10:06Greenville
19h 04m
2 stops
MAN10:10Manchester
3 Feb
MAN13:30Manchester
13h 22m
1 stop
GSP21:52Greenville
£474
Find similar
Delta
15 Jan
GSP06:50Greenville
22h 40m
1 stop
MAN10:30Manchester
19 Jan
MAN09:00Manchester
14h 39m
1 stop
GSP18:39Greenville
£475
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 14 November 2025.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Fri 23/1

05:40-10:30

1 stop23h 50m

Manchester

Mon 2/2

09:00-23:55

1 stop19h 55m

£471

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Thu 15/1

11:49-23:20

2 stops30h 31m

Manchester

Mon 19/1

11:15-23:48

2 stops17h 33m

£473

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Fri 23/1

17:34-23:20

2 stops24h 46m

Manchester

Mon 2/2

06:25-23:48

2 stops22h 23m

£473

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Tue 20/1

10:51-10:20

2 stops18h 29m

Manchester

Mon 2/2

06:10-16:52

2 stops15h 42m

£483

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Thu 22/1

11:00-09:10

2 stops17h 10m

Manchester

Sun 1/2

09:40-20:59

2 stops16h 19m

£484

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 29/4

10:20-09:50

2 stops18h 30m

Manchester

Wed 6/5

07:00-16:45

1 stop14h 45m

£496

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 17/3

14:51-10:20

2 stops15h 29m

Manchester

Sun 22/3

18:45-17:55

2 stops51h 10m

£499

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 26/2

23:00-19:05

1 stop15h 05m

Manchester

Wed 4/3

07:50-19:05

1 stop16h 15m

£502

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 26/2

18:30-11:00

1 stop11h 30m

Manchester

Wed 4/3

09:50-19:05

1 stop14h 15m

£503

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Tue 24/3

11:10-10:20

3 stops19h 10m

Manchester

Thu 2/4

07:00-20:31

2 stops42h 31m

£560

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

In general, October is the cheapest month to fly from South Carolina to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £493. If you aren’t able to travel to Manchester during the month of October, then flying in September is also cheap. Prices for this month can be found on momondo for an average of £564.

What is the cheapest day to depart on your flight to Manchester?

The cheapest day to depart from South Carolina to Manchester is on a Thursday. Travellers who choose to depart for Manchester on a Thursday will often find tickets for as low as £817. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around £1,108. These prices are subject to change though, so be sure to set up a Price Alert for flights to Manchester.

What is the cheapest time of day to depart on your flight to Manchester?

The cheapest time of day to fly to Manchester is at midday when flights can be purchased for as low as £817. Flights to Manchester are more costly in the afternoon, with an average ticket price of £977. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on South Carolina to Manchester flights?

You could potentially save up to 41% on your flight if you consider stops on a South Carolina to Manchester flight.

Cheap South Carolina to Manchester flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Manchester

Direct flights

None
There are no direct flights from South Carolina to Manchester. There are no popular flight routes from South Carolina to Manchester.
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  • When did momondo last update prices for flights from South Carolina to Manchester Airport?

    Prices for flights from South Carolina to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Manchester Airport?

  • How old do you have to be to fly from South Carolina to Manchester Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Manchester

Compare and see reviews for airlines that fly from South Carolina to Manchester with momondo
Airline
Rating
Free Cancellation
Price
Virgin AtlanticPriceFrom £488Free CancellationRating
7.5
673 reviews
Search Virgin Atlantic flights

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Southport
Harrogate
Lincoln
Bradford
Derby
Morecambe
Aberystwyth
Skipton
Bolton
Preston
Stoke-on-Trent
Shrewsbury
Kendal
Ludlow

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Manchester?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Manchester. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Manchester with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Manchester flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Manchester right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Manchester from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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