Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to Manchester from £325

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Manchester departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Voted winner of Europe's Best Travel App 2023

Save money when you book flights with momondo

Big names, great deals

Big names, great deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customise your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from South Carolina to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
Lufthansa Logo
16:41 - 23:20
CHS
-
MAN
25h 39m2 stops
Lufthansa Logo
11:15 - 23:44
MAN
-
CHS
17h 29m2 stops
£454Lufthansa
Mon, 2 Feb - Wed, 25 Feb
British Airways Logo
06:00 - 10:55
SAV
-
MAN
23h 55m2 stops
British Airways Logo
14:45 - 23:58
MAN
-
SAV
37h 13m2 stops
£460British Airways
Wed, 4 Mar - Tue, 10 Mar
Delta Logo
16:31 - 10:30
SAV
-
MAN
12h 59m1 stop
Delta Logo
13:00 - 22:02
MAN
-
SAV
13h 02m1 stop
£464Delta
Wed, 4 Mar - Tue, 10 Mar
Delta Logo
10:06 - 10:30
GSP
-
MAN
19h 24m1 stop
Delta Logo
13:30 - 18:37
MAN
-
GSP
34h 07m1 stop
£464Delta
Thu, 5 Feb - Tue, 17 Feb
Multiple Airlines Logo
15:28 - 10:10
CHS
-
MAN
13h 42m2 stops
Multiple Airlines Logo
13:00 - 21:02
MAN
-
CHS
13h 02m1 stop
£468Multiple Airlines
Mon, 2 Feb - Wed, 25 Feb
Multiple Airlines Logo
09:06 - 11:00
CLT
-
MAN
20h 54m2 stops
Multiple Airlines Logo
11:55 - 23:59
MAN
-
CLT
17h 04m2 stops
£472Multiple Airlines
Fri, 30 Jan - Fri, 6 Feb
American Airlines Logo
15:29 - 16:25
HHH
-
MAN
19h 56m2 stops
American Airlines Logo
06:15 - 12:20
MAN
-
HHH
35h 05m2 stops
£474American Airlines
Sat, 31 Jan - Sat, 7 Feb
American Airlines Logo
23:45 - 15:35
CLT
-
MAN
10h 50m1 stop
American Airlines Logo
08:10 - 16:00
MAN
-
CLT
12h 50m1 stop
£477American Airlines
Wed, 6 May - Thu, 14 May
United Airlines Logo
14:13 - 10:20
SAV
-
MAN
15h 07m2 stops
United Airlines Logo
06:10 - 14:47
MAN
-
SAV
37h 37m2 stops
£477United Airlines
Fri, 23 Jan - Tue, 27 Jan
United Airlines Logo
17:34 - 10:20
GSP
-
MAN
35h 46m2 stops
United Airlines Logo
06:10 - 10:01
MAN
-
GSP
32h 51m2 stops
£477United Airlines
Thu, 5 Feb - Wed, 11 Feb

Lufthansa flights from South Carolina to Manchester

Our best Lufthansa deals on South Carolina to Manchester flight tickets
Lufthansa
2 Feb
CHS16:41Charleston
25h 39m
2 stops
MAN23:20Manchester
25 Feb
MAN11:15Manchester
17h 29m
2 stops
CHS23:44Charleston
£454
Find similar
Lufthansa
5 May
CLT18:40Charlotte Douglas
17h 25m
1 stop
MAN17:05Manchester
14 May
MAN07:00Manchester
14h 45m
1 stop
CLT16:45Charlotte Douglas
£462
Find similar
Lufthansa
5 May
CLT19:47Charlotte Douglas
16h 18m
2 stops
MAN17:05Manchester
14 May
MAN07:00Manchester
14h 45m
1 stop
CLT16:45Charlotte Douglas
£465
Find similar

Delta flights from South Carolina to Manchester

Our best Delta deals on South Carolina to Manchester flight tickets
Delta
5 Feb
GSP10:06Greenville
19h 24m
1 stop
MAN10:30Manchester
17 Feb
MAN13:30Manchester
34h 07m
1 stop
GSP18:37Greenville
£464
Find similar
Delta
5 Feb
GSP12:00Greenville
17h 30m
1 stop
MAN10:30Manchester
11 Feb
MAN10:25Manchester
27h 51m
2 stops
GSP09:16Greenville
£468
Find similar
Delta
2 Feb
CHS06:30Charleston
19h 00m
1 stop
MAN06:30Manchester
25 Feb
MAN13:00Manchester
27h 59m
1 stop
CHS11:59Charleston
£469
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 17 December 2025.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Mon 2/2

16:41-23:20

2 stops25h 39m

Manchester

Wed 25/2

11:15-23:44

2 stops17h 29m

£454

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 4/3

06:00-10:55

2 stops23h 55m

Manchester

Tue 10/3

14:45-23:58

2 stops37h 13m

£460

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 4/3

16:31-10:30

1 stop12h 59m

Manchester

Tue 10/3

13:00-22:02

1 stop13h 02m

£464

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Thu 5/2

10:06-10:30

1 stop19h 24m

Manchester

Tue 17/2

13:30-18:37

1 stop34h 07m

£464

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Mon 2/2

15:28-10:10

2 stops13h 42m

Manchester

Wed 25/2

13:00-21:02

1 stop13h 02m

£468

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Fri 30/1

09:06-11:00

2 stops20h 54m

Manchester

Fri 6/2

11:55-23:59

2 stops17h 04m

£472

Hilton Head IslandManchester

HHH - MAN

HHHMAN

Hilton Head Island

Sat 31/1

15:29-16:25

2 stops19h 56m

Manchester

Sat 7/2

06:15-12:20

2 stops35h 05m

£474

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

23:45-15:35

1 stop10h 50m

Manchester

Thu 14/5

08:10-16:00

1 stop12h 50m

£477

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Fri 23/1

14:13-10:20

2 stops15h 07m

Manchester

Tue 27/1

06:10-14:47

2 stops37h 37m

£477

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Thu 5/2

17:34-10:20

2 stops35h 46m

Manchester

Wed 11/2

06:10-10:01

2 stops32h 51m

£477

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Manchester from

How to get the cheapest flight ticket from South Carolina to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Manchester?

In general, November is the cheapest month to fly from South Carolina to Manchester. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around £483. If you aren’t able to travel to Manchester during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of £484.

What is the cheapest day to depart on your flight to Manchester?

The cheapest day to depart from South Carolina to Manchester is on a Thursday. Travellers who choose to depart for Manchester on a Thursday will often find tickets for as low as £802. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around £1,088. These prices are subject to change though, so be sure to set up a Price Alert for flights to Manchester.

What is the cheapest time of day to depart on your flight to Manchester?

The cheapest time of day to fly to Manchester is at midday when flights can be purchased for as low as £802. Flights to Manchester are more costly in the afternoon, with an average ticket price of £959. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on South Carolina to Manchester flights?

You could potentially save up to 49% on your flight if you consider stops on a South Carolina to Manchester flight.

Cheap South Carolina to Manchester flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Manchester

Fastest flight time

13h 43m

Direct flights

None
The fastest flight from South Carolina to Manchester takes 13h 43m
There are no direct flights from South Carolina to Manchester. There are no popular flight routes from South Carolina to Manchester.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Manchester Airport?

    Prices for flights from South Carolina to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from South Carolina to Manchester Airport?

  • How old do you have to be to fly from South Carolina to Manchester Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Manchester

Compare and see reviews for airlines that fly from South Carolina to Manchester with momondo
Airline
Rating
Free Cancellation
Price
Virgin AtlanticPriceFrom £479Free CancellationRating
7.5
675 reviews
Search Virgin Atlantic flights

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Southport
Leicester
Harrogate
Lincoln
Bradford
Derby
Aberystwyth
Morecambe
Bolton
Skipton
Preston
Shrewsbury
Stoke-on-Trent
Kendal
Ludlow

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Manchester?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from South Carolina to Manchester. momondo saves you time and could save you money on your trip.

Can I find flights from South Carolina to Manchester with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Manchester flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Manchester?

momondo provides multiple filters to help you find the best flight to Manchester from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Manchester right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Manchester from South Carolina. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Manchester trip

We make it super easy to schedule, organise and travel with friends or family. Trips is free – and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 16/1
Fri 23/1
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United Kingdom