Travelling from most locations, it is best to book your flight to Italy during the month of January for the best deal, although there are other times of the year which offer great deals as well.
In general, most flyers find the cheapest time to book a flight to Italy is about 60 days prior.
Most of our users find that booking their departure to Italy on a Tuesday is the cheapest. Conversely, departing on a Friday seems to be the most expensive.
On average you can find the best deals on plane tickets to Italy when looking for flights with midday departure times.