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Cheap flights from Des Moines to Manchester from £273

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Manchester departing on 15/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags
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Find the cheapest flights from Des Moines to Manchester

Cheap return flights

Enter your travel dates to find the best prices.
Lufthansa Logo
11:40 - 17:35
DSM
-
MAN
23h 55m
2 stops
Lufthansa Logo
17:55 - 21:23
MAN
-
DSM
33h 28m
2 stops
£725Lufthansa
Tue, 12 May - Tue, 19 May
Lufthansa Logo
19:05 - 17:35
DSM
-
MAN
16h 30m
2 stops
Lufthansa Logo
07:00 - 21:23
MAN
-
DSM
20h 23m
2 stops
£729Lufthansa
Tue, 12 May - Tue, 19 May
Lufthansa Logo
11:40 - 17:35
DSM
-
MAN
23h 55m
2 stops
Lufthansa Logo
05:55 - 18:05
MAN
-
DSM
18h 10m
2 stops
£734Lufthansa
Tue, 12 May - Tue, 19 May
American Airlines Logo
14:16 - 09:50
DSM
-
MAN
13h 34m
2 stops
American Airlines Logo
06:55 - 19:33
MAN
-
DSM
18h 38m
2 stops
£738American Airlines
Tue, 12 May - Tue, 19 May
Lufthansa Logo
19:05 - 23:15
DSM
-
MAN
22h 10m
2 stops
Lufthansa Logo
17:55 - 21:23
MAN
-
DSM
33h 28m
2 stops
£743Lufthansa
Mon, 11 May - Mon, 18 May
United Airlines Logo
06:15 - 10:25
DSM
-
MAN
22h 10m
2 stops
United Airlines Logo
06:05 - 18:05
MAN
-
DSM
18h 00m
2 stops
£753United Airlines
Tue, 12 May - Tue, 19 May
Lufthansa Logo
19:05 - 17:35
DSM
-
MAN
16h 30m
2 stops
Lufthansa Logo
10:35 - 21:23
MAN
-
DSM
16h 48m
2 stops
£754Lufthansa
Tue, 12 May - Tue, 19 May
Virgin Atlantic Logo
13:04 - 10:00
DSM
-
MAN
14h 56m
2 stops
Virgin Atlantic Logo
13:00 - 22:32
MAN
-
DSM
15h 32m
1 stop
£755Virgin Atlantic
Tue, 12 May - Tue, 19 May
United Airlines Logo
15:20 - 10:25
DSM
-
MAN
13h 05m
2 stops
United Airlines Logo
10:35 - 20:16
MAN
-
DSM
39h 41m
2 stops
£762United Airlines
Mon, 11 May - Mon, 18 May
Lufthansa Logo
19:05 - 23:15
DSM
-
MAN
22h 10m
2 stops
Lufthansa Logo
17:55 - 21:23
MAN
-
DSM
33h 28m
2 stops
£769Lufthansa
Mon, 11 May - Mon, 18 May

Delta flights from Des Moines to Manchester

Our best Delta deals on Des Moines to Manchester flight tickets
Delta
19 May
DSM07:34Des Moines
18h 46m
1 stop
MAN08:20Manchester
26 May
MAN13:00Manchester
15h 32m
1 stop
DSM22:32Des Moines
£842
Delta
14 May
DSM06:15Des Moines
20h 05m
2 stops
MAN08:20Manchester
21 May
MAN13:00Manchester
28h 08m
1 stop
DSM11:08Des Moines
£882
Delta
9 May
DSM07:01Des Moines
20h 59m
2 stops
MAN10:00Manchester
16 May
MAN13:15Manchester
27h 53m
1 stop
DSM11:08Des Moines
£898

Lufthansa flights from Des Moines to Manchester

Our best Lufthansa deals on Des Moines to Manchester flight tickets
Lufthansa
12 May
DSM11:40Des Moines
23h 55m
2 stops
MAN17:35Manchester
19 May
MAN17:55Manchester
33h 28m
2 stops
DSM21:23Des Moines
£725
Lufthansa
12 May
DSM19:05Des Moines
16h 30m
2 stops
MAN17:35Manchester
19 May
MAN07:00Manchester
20h 23m
2 stops
DSM21:23Des Moines
£729
Lufthansa
12 May
DSM11:40Des Moines
23h 55m
2 stops
MAN17:35Manchester
19 May
MAN05:55Manchester
18h 10m
2 stops
DSM18:05Des Moines
£734

momondo Fare Finder

 
Customise your flight search to find flights from Des Moines to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 1 April 2026.
Use the filters below to find and compare flights from Des Moines to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 12/5

11:40-17:35

2 stops23h 55m

Manchester

Tue 19/5

17:55-21:23

2 stops33h 28m

£725

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 12/5

19:05-17:35

2 stops16h 30m

Manchester

Tue 19/5

07:00-21:23

2 stops20h 23m

£729

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 12/5

11:40-17:35

2 stops23h 55m

Manchester

Tue 19/5

05:55-18:05

2 stops18h 10m

£734

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 12/5

14:16-09:50

2 stops13h 34m

Manchester

Tue 19/5

06:55-19:33

2 stops18h 38m

£738

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Mon 11/5

19:05-23:15

2 stops22h 10m

Manchester

Mon 18/5

17:55-21:23

2 stops33h 28m

£743

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 12/5

06:15-10:25

2 stops22h 10m

Manchester

Tue 19/5

06:05-18:05

2 stops18h 00m

£753

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 12/5

19:05-17:35

2 stops16h 30m

Manchester

Tue 19/5

10:35-21:23

2 stops16h 48m

£754
Fastest return journey

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Tue 12/5

13:04-10:00

2 stops14h 56m

Manchester

Tue 19/5

13:00-22:32

1 stop15h 32m

£755

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Mon 11/5

15:20-10:25

2 stops13h 05m

Manchester

Mon 18/5

10:35-20:16

2 stops39h 41m

£762

Des MoinesManchester

DSM - MAN

DSMMAN

Des Moines

Mon 11/5

19:05-23:15

2 stops22h 10m

Manchester

Mon 18/5

17:55-21:23

2 stops33h 28m

£769

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Manchester from

How to get the cheapest flight ticket from Des Moines to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Manchester?

Air Canada, American Airlines, and Lufthansa are the most popular carriers operating from Des Moines to Manchester

When to book flights from Des Moines to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Des Moines to Manchester (DSM to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Manchester

Fastest flight time

19h 42m

Direct flights

None
The fastest flight from Des Moines to Manchester takes 19h 42m
There are no direct flights from Des Moines to Manchester. There are no popular flight routes from Des Moines to Manchester.
Search flight deals

  • How far is Des Moines to Manchester by plane?

    The distance between Des Moines and Manchester is about 4038.6 mi. Typically, this will take 19h 42m by plane in normal conditions.

  • When did momondo last update prices for flights from Des Moines Airport to Manchester Airport?

    Prices for flights from Des Moines Airport to Manchester Airport refresh daily.

  • How old do you have to be to fly from Des Moines Airport to Manchester Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Chester
Windermere
Sheffield
Leicester
Southport
Harrogate
Derby
Lincoln
Bradford
Shrewsbury
Morecambe
Aberystwyth
Preston
Skipton
Bolton
Ludlow
Kendal
Stoke-on-Trent

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Manchester?

It is quick and easy to find Des Moines to Manchester flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Manchester that suits you.

Can I find flights from Des Moines to Manchester with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Manchester from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Manchester?

momondo helps you find the best flight between Des Moines and Manchester by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Manchester right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Manchester flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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