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Cheap flights from Southampton to Chicago from £326

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to Chicago departing on 19/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags
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Find the cheapest flights from Southampton to Chicago

Cheap return flights

Enter your travel dates to find the best prices.
KLM Logo
17:30 - 17:37
SOU
-
MDW
30h 07m
2 stops
KLM Logo
13:29 - 08:20
MDW
-
SOU
36h 51m
2 stops
£669KLM
Sat, 28 Feb - Sat, 7 Mar
KLM Logo
09:25 - 20:17
SOU
-
ORD
16h 52m
2 stops
KLM Logo
14:05 - 08:20
ORD
-
SOU
36h 15m
2 stops
£669KLM
Sat, 28 Feb - Sat, 7 Mar
KLM Logo
17:30 - 14:20
SOU
-
ORD
26h 50m
1 stop
KLM Logo
16:25 - 08:50
ORD
-
SOU
10h 25m
1 stop
£670KLM
Sat, 28 Feb - Sat, 7 Mar
KLM Logo
09:25 - 20:17
SOU
-
ORD
16h 52m
2 stops
KLM Logo
16:25 - 08:50
ORD
-
SOU
10h 25m
1 stop
£674KLM
Sat, 28 Feb - Sat, 7 Mar
British Airways Logo
12:25 - 19:15
SOU
-
ORD
12h 50m
1 stop
British Airways Logo
16:50 - 08:45
ORD
-
SOU
10h 55m
1 stop
£727British Airways
Wed, 4 Mar - Sun, 8 Mar
British Airways Logo
12:25 - 19:15
SOU
-
ORD
12h 50m
1 stop
British Airways Logo
20:40 - 19:40
ORD
-
SOU
18h 00m
1 stop
£729British Airways
Wed, 4 Mar - Sun, 8 Mar
British Airways Logo
20:10 - 19:15
SOU
-
ORD
29h 05m
1 stop
British Airways Logo
20:40 - 11:55
ORD
-
SOU
10h 15m
1 stop
£733British Airways
Thu, 5 Mar - Mon, 9 Mar
British Airways Logo
16:05 - 14:00
SOU
-
ORD
27h 55m
1 stop
British Airways Logo
22:45 - 08:10
ORD
-
SOU
28h 25m
2 stops
£743British Airways
Thu, 5 Mar - Mon, 9 Mar
British Airways Logo
12:25 - 19:15
SOU
-
ORD
12h 50m
1 stop
British Airways Logo
16:50 - 12:05
ORD
-
SOU
14h 15m
2 stops
£747British Airways
Wed, 4 Mar - Sun, 8 Mar
British Airways Logo
12:25 - 19:15
SOU
-
ORD
12h 50m
1 stop
British Airways Logo
16:50 - 12:05
ORD
-
SOU
14h 15m
2 stops
£749British Airways
Wed, 4 Mar - Sun, 8 Mar

British Airways flights from Southampton to Chicago

Our best British Airways deals on Southampton to Chicago flight tickets
British Airways
4 Mar
SOU12:25Southampton Eastleigh
12h 50m
1 stop
ORD19:15Chicago O'Hare Intl
8 Mar
ORD16:50Chicago O'Hare Intl
10h 55m
1 stop
SOU08:45Southampton Eastleigh
£727
British Airways
4 Mar
SOU12:25Southampton Eastleigh
12h 50m
1 stop
ORD19:15Chicago O'Hare Intl
8 Mar
ORD20:40Chicago O'Hare Intl
18h 00m
1 stop
SOU19:40Southampton Eastleigh
£729
British Airways
5 Mar
SOU20:10Southampton Eastleigh
29h 05m
1 stop
ORD19:15Chicago O'Hare Intl
9 Mar
ORD20:40Chicago O'Hare Intl
10h 15m
1 stop
SOU11:55Southampton Eastleigh
£733

KLM flights from Southampton to Chicago

Our best KLM deals on Southampton to Chicago flight tickets
KLM
28 Feb
SOU09:25Southampton Eastleigh
16h 52m
2 stops
ORD20:17Chicago O'Hare Intl
7 Mar
ORD14:05Chicago O'Hare Intl
36h 15m
2 stops
SOU08:20Southampton Eastleigh
£669
KLM
28 Feb
SOU17:30Southampton Eastleigh
26h 50m
1 stop
ORD14:20Chicago O'Hare Intl
7 Mar
ORD16:25Chicago O'Hare Intl
10h 25m
1 stop
SOU08:50Southampton Eastleigh
£670
KLM
28 Feb
SOU09:25Southampton Eastleigh
16h 52m
2 stops
ORD20:17Chicago O'Hare Intl
7 Mar
ORD16:25Chicago O'Hare Intl
10h 25m
1 stop
SOU08:50Southampton Eastleigh
£674

momondo Fare Finder

 
Customise your flight search to find flights from Southampton to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 2 February 2026.
Use the filters below to find and compare flights from Southampton to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonChicago

SOU - MDW

SOUMDW

Southampton Eastleigh

Sat 28/2

17:30-17:37

2 stops30h 07m

Chicago Midway

Sat 7/3

13:29-08:20

2 stops36h 51m

£669

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Sat 28/2

09:25-20:17

2 stops16h 52m

Chicago O'Hare Intl

Sat 7/3

14:05-08:20

2 stops36h 15m

£669

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Sat 28/2

17:30-14:20

1 stop26h 50m

Chicago O'Hare Intl

Sat 7/3

16:25-08:50

1 stop10h 25m

£670

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Sat 28/2

09:25-20:17

2 stops16h 52m

Chicago O'Hare Intl

Sat 7/3

16:25-08:50

1 stop10h 25m

£674

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Wed 4/3

12:25-19:15

1 stop12h 50m

Chicago O'Hare Intl

Sun 8/3

16:50-08:45

1 stop10h 55m

£727

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Wed 4/3

12:25-19:15

1 stop12h 50m

Chicago O'Hare Intl

Sun 8/3

20:40-19:40

1 stop18h 00m

£729

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Thu 5/3

20:10-19:15

1 stop29h 05m

Chicago O'Hare Intl

Mon 9/3

20:40-11:55

1 stop10h 15m

£733

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Thu 5/3

16:05-14:00

1 stop27h 55m

Chicago O'Hare Intl

Mon 9/3

22:45-08:10

2 stops28h 25m

£743

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Wed 4/3

12:25-19:15

1 stop12h 50m

Chicago O'Hare Intl

Sun 8/3

16:50-12:05

2 stops14h 15m

£747

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Wed 4/3

12:25-19:15

1 stop12h 50m

Chicago O'Hare Intl

Sun 8/3

16:50-12:05

2 stops14h 15m

£749

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Southampton to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Wednesday when prices can be found for as low as £608. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Chicago is Saturday, with ticket prices averaging around £647.

What is the cheapest time of day to depart on your flight to Chicago?

Flying to Chicago from Southampton at midday is the least expensive time of day to depart. momondo users have found prices as low as £622 when looking at flights departing at midday. Flights in the afternoon are often more expensive, with an average ticket price of £657.

When to book flights from Southampton to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Southampton to Chicago (SOU to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to Chicago

Fastest flight time

12h 50m

Direct flights

None
The fastest flight from Southampton to Chicago takes 12h 50m
There are no direct flights from Southampton to Chicago. There are no popular flight routes from Southampton to Chicago.
Search flight deals

  • How far is Southampton Eastleigh to Chicago by plane?

    The distance between Southampton Eastleigh and Chicago is about 3914.9 mi. 12h 50m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to Chicago?

    Prices for flights from Southampton Eastleigh Airport to Chicago are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to Chicago?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Southampton Eastleigh Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The required travel and health documents for your Chicago trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Southampton to Chicago . Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Southampton to Chicago with flexible booking policies on momondo?

All flight searches from Southampton to Chicago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Southampton to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Southampton to Chicago.

I’m not ready to book a flight from Southampton to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Southampton to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport