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Cheap flights from Southampton to Chicago from £455

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to Chicago departing on 21/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags
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Find the cheapest flights from Southampton to Chicago

Cheap return flights

Enter your travel dates to find the best prices.
British Airways Logo
09:20 - 18:25
SOU
-
ORD
15h 05m
1 stop
British Airways Logo
20:10 - 19:30
ORD
-
SOU
17h 20m
1 stop
£601British Airways
Wed, 11 Nov - Sun, 15 Nov
British Airways Logo
09:20 - 18:25
SOU
-
ORD
15h 05m
1 stop
British Airways Logo
20:10 - 19:30
ORD
-
SOU
17h 20m
1 stop
£603British Airways
Wed, 11 Nov - Sun, 15 Nov
British Airways Logo
09:20 - 18:25
SOU
-
ORD
15h 05m
1 stop
British Airways Logo
20:10 - 19:30
ORD
-
SOU
17h 20m
1 stop
£604British Airways
Wed, 11 Nov - Sun, 15 Nov
British Airways Logo
20:00 - 14:14
SOU
-
ORD
48h 14m
2 stops
British Airways Logo
15:55 - 08:40
ORD
-
SOU
10h 45m
1 stop
£606British Airways
Wed, 11 Nov - Sun, 15 Nov
Delta Logo
17:20 - 14:15
SOU
-
ORD
26h 55m
1 stop
Delta Logo
08:25 - 08:35
ORD
-
SOU
18h 10m
2 stops
£710Delta
Mon, 31 Aug - Wed, 9 Sep
Delta Logo
09:05 - 18:01
SOU
-
MDW
14h 56m
2 stops
Delta Logo
17:45 - 16:50
MDW
-
SOU
17h 05m
2 stops
£713Delta
Tue, 1 Sep - Tue, 8 Sep
Delta Logo
18:05 - 18:07
SOU
-
MDW
30h 02m
2 stops
Delta Logo
18:58 - 08:45
MDW
-
SOU
31h 47m
2 stops
£850Delta
Fri, 10 Jul - Tue, 14 Jul
KLM Logo
09:15 - 22:36
SOU
-
MDW
19h 21m
2 stops
KLM Logo
19:25 - 17:35
MDW
-
SOU
16h 10m
2 stops
£1,411KLM
Wed, 5 Aug - Wed, 12 Aug
KLM Logo
09:15 - 22:36
SOU
-
MDW
19h 21m
2 stops
KLM Logo
19:25 - 17:35
MDW
-
SOU
16h 10m
2 stops
£1,728KLM
Wed, 5 Aug - Wed, 12 Aug
KLM Logo
09:15 - 22:36
SOU
-
MDW
19h 21m
2 stops
KLM Logo
19:25 - 17:35
MDW
-
SOU
16h 10m
2 stops
£1,731KLM
Wed, 5 Aug - Wed, 12 Aug

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British Airways flights from Southampton to Chicago

Our best British Airways deals on Southampton to Chicago flight tickets
British Airways
11 Nov
SOU09:20Southampton Eastleigh
15h 05m
1 stop
ORD18:25Chicago O'Hare Intl
15 Nov
ORD20:10Chicago O'Hare Intl
17h 20m
1 stop
SOU19:30Southampton Eastleigh
£601
British Airways
11 Nov
SOU09:20Southampton Eastleigh
15h 05m
1 stop
ORD18:25Chicago O'Hare Intl
15 Nov
ORD20:10Chicago O'Hare Intl
17h 20m
1 stop
SOU19:30Southampton Eastleigh
£603
British Airways
11 Nov
SOU09:20Southampton Eastleigh
15h 05m
1 stop
ORD18:25Chicago O'Hare Intl
15 Nov
ORD20:10Chicago O'Hare Intl
17h 20m
1 stop
SOU19:30Southampton Eastleigh
£604

Delta flights from Southampton to Chicago

Our best Delta deals on Southampton to Chicago flight tickets
Delta
31 Aug
SOU17:20Southampton Eastleigh
26h 55m
1 stop
ORD14:15Chicago O'Hare Intl
9 Sept
ORD08:25Chicago O'Hare Intl
18h 10m
2 stops
SOU08:35Southampton Eastleigh
£710
Delta
1 Sept
SOU09:05Southampton Eastleigh
14h 56m
2 stops
MDW18:01Chicago Midway
8 Sept
MDW17:45Chicago Midway
17h 05m
2 stops
SOU16:50Southampton Eastleigh
£713
Delta
3 Sept
SOU09:05Southampton Eastleigh
11h 10m
1 stop
ORD14:15Chicago O'Hare Intl
9 Sept
ORD12:29Chicago O'Hare Intl
14h 06m
2 stops
SOU08:35Southampton Eastleigh
£740

momondo Fare Finder

 
Customise your flight search to find flights from Southampton to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 27 June 2026.
Use the filters below to find and compare flights from Southampton to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Wed 11/11

09:20-18:25

1 stop15h 05m

Chicago O'Hare Intl

Sun 15/11

20:10-19:30

1 stop17h 20m

£601

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Wed 11/11

09:20-18:25

1 stop15h 05m

Chicago O'Hare Intl

Sun 15/11

20:10-19:30

1 stop17h 20m

£603

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Wed 11/11

09:20-18:25

1 stop15h 05m

Chicago O'Hare Intl

Sun 15/11

20:10-19:30

1 stop17h 20m

£604

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Wed 11/11

20:00-14:14

2 stops48h 14m

Chicago O'Hare Intl

Sun 15/11

15:55-08:40

1 stop10h 45m

£606

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Mon 31/8

17:20-14:15

1 stop26h 55m

Chicago O'Hare Intl

Wed 9/9

08:25-08:35

2 stops18h 10m

£710
Fastest return journey

SouthamptonChicago

SOU - MDW

SOUMDW

Southampton Eastleigh

Tue 1/9

09:05-18:01

2 stops14h 56m

Chicago Midway

Tue 8/9

17:45-16:50

2 stops17h 05m

£713

SouthamptonChicago

SOU - MDW

SOUMDW

Southampton Eastleigh

Fri 10/7

18:05-18:07

2 stops30h 02m

Chicago Midway

Tue 14/7

18:58-08:45

2 stops31h 47m

£850

SouthamptonChicago

SOU - MDW

SOUMDW

Southampton Eastleigh

Wed 5/8

09:15-22:36

2 stops19h 21m

Chicago Midway

Wed 12/8

19:25-17:35

2 stops16h 10m

£1,411

SouthamptonChicago

SOU - MDW

SOUMDW

Southampton Eastleigh

Wed 5/8

09:15-22:36

2 stops19h 21m

Chicago Midway

Wed 12/8

19:25-17:35

2 stops16h 10m

£1,728

SouthamptonChicago

SOU - MDW

SOUMDW

Southampton Eastleigh

Wed 5/8

09:15-22:36

2 stops19h 21m

Chicago Midway

Wed 12/8

19:25-17:35

2 stops16h 10m

£1,731

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Southampton to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Wednesday when prices can be found for as low as £678. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Chicago is Sunday, with ticket prices averaging around £695.

What is the cheapest time of day to depart on your flight to Chicago?

Flying to Chicago from Southampton at midday is the least expensive time of day to depart. momondo users have found prices as low as £670 when looking at flights departing at midday. Flights in the afternoon are often more expensive, with an average ticket price of £700.

When to book flights from Southampton to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Southampton to Chicago (SOU to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to Chicago

Fastest flight time

11h 10m

Direct flights

None
The fastest flight from Southampton to Chicago takes 11h 10m
There are no direct flights from Southampton to Chicago. There are no popular flight routes from Southampton to Chicago.
Search flight deals

Frequently asked questions about flying from Southampton to Chicago

  • How far is Southampton Eastleigh to Chicago by plane?

    The distance between Southampton Eastleigh and Chicago is about 3914.9 mi. 11h 10m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to Chicago?

    Prices for flights from Southampton Eastleigh Airport to Chicago are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to Chicago?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Southampton Eastleigh Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The required travel and health documents for your Chicago trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Travelling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Schererville

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to Chicago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Southampton to Chicago . Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Southampton to Chicago with flexible booking policies on momondo?

All flight searches from Southampton to Chicago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Southampton to Chicago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Southampton to Chicago.

I’m not ready to book a flight from Southampton to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Southampton to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport