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Cheap flights from Southampton to San Francisco from £357

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to San Francisco departing on 11/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags
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Cheap return flights

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Delta Logo
17:30 - 11:50SOU-SFO
26h 20m1 stop
Delta Logo
22:54 - 17:05SFO-SOU
34h 11m2 stops
£508Delta
Find Deal
tir., 23 dec. - ons., 7 jan.
Virgin Atlantic Logo
17:35 - 11:50SOU-SFO
26h 15m1 stop
Virgin Atlantic Logo
14:05 - 17:00SFO-SOU
18h 55m2 stops
£514Virgin Atlantic
Find Deal
ons., 21 jan. - søn., 25 jan.
Virgin Atlantic Logo
17:35 - 11:50SOU-SFO
26h 15m1 stop
Virgin Atlantic Logo
06:00 - 08:50SFO-SOU
18h 50m2 stops
£515Virgin Atlantic
Find Deal
ons., 21 jan. - søn., 25 jan.
Virgin Atlantic Logo
17:35 - 16:09SOU-SFO
30h 34m2 stops
Virgin Atlantic Logo
14:05 - 17:00SFO-SOU
18h 55m2 stops
£518Virgin Atlantic
Find Deal
ons., 21 jan. - søn., 25 jan.
Virgin Atlantic Logo
17:35 - 17:47SOU-SFO
32h 12m2 stops
Virgin Atlantic Logo
08:00 - 08:50SFO-SOU
16h 50m2 stops
£520Virgin Atlantic
Find Deal
ons., 21 jan. - søn., 25 jan.
Delta Logo
17:45 - 11:50SOU-SFO
26h 05m1 stop
Delta Logo
22:55 - 08:05SFO-SOU
26h 10m2 stops
£522Delta
Find Deal
søn., 1 mar. - ons., 11 mar.
Delta Logo
09:25 - 11:50SOU-SFO
34h 25m1 stop
Delta Logo
13:55 - 17:00SFO-SOU
19h 05m1 stop
£524Delta
Find Deal
ons., 21 jan. - søn., 25 jan.
Delta Logo
08:40 - 20:57SOU-SFO
20h 17m2 stops
Delta Logo
22:50 - 08:10SFO-SOU
26h 20m2 stops
£527Delta
Find Deal
tir., 3 mar. - søn., 8 mar.
Virgin Atlantic Logo
09:25 - 23:04SOU-SFO
21h 39m2 stops
Virgin Atlantic Logo
05:45 - 08:50SFO-SOU
19h 05m2 stops
£527Virgin Atlantic
Find Deal
ons., 21 jan. - søn., 25 jan.
Delta Logo
17:30 - 11:50SOU-SFO
26h 20m1 stop
Delta Logo
14:55 - 17:00SFO-SOU
19h 05m1 stop
£535Delta
Find Deal
lør., 28 feb. - man., 9 mar.

British Airways flights from Southampton to San Francisco

Our best British Airways deals on Southampton to San Francisco flight tickets
British Airways
28 Feb
SOU09:30Southampton Eastleigh
14h 05m
1 stop
SFO15:35San Francisco
4 Mar
SFO17:20San Francisco
14h 15m
1 stop
SOU15:35Southampton Eastleigh
£707
Find similar
British Airways
2 Mar
SOU09:30Southampton Eastleigh
14h 05m
1 stop
SFO15:35San Francisco
6 Mar
SFO17:20San Francisco
31h 25m
1 stop
SOU08:45Southampton Eastleigh
£712
Find similar
British Airways
1 Mar
SOU20:10Southampton Eastleigh
27h 25m
1 stop
SFO15:35San Francisco
7 Mar
SFO17:20San Francisco
31h 25m
1 stop
SOU08:45Southampton Eastleigh
£718
Find similar

Virgin Atlantic flights from Southampton to San Francisco

Our best Virgin Atlantic deals on Southampton to San Francisco flight tickets
Virgin Atlantic
21 Jan
SOU17:35Southampton Eastleigh
26h 15m
1 stop
SFO11:50San Francisco
25 Jan
SFO06:00San Francisco
18h 50m
2 stops
SOU08:50Southampton Eastleigh
£515
Find similar
Virgin Atlantic
21 Jan
SOU17:35Southampton Eastleigh
32h 12m
2 stops
SFO17:47San Francisco
25 Jan
SFO08:00San Francisco
16h 50m
2 stops
SOU08:50Southampton Eastleigh
£520
Find similar
Virgin Atlantic
21 Jan
SOU17:35Southampton Eastleigh
26h 15m
1 stop
SFO11:50San Francisco
25 Jan
SFO05:45San Francisco
19h 05m
2 stops
SOU08:50Southampton Eastleigh
£524
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 25 november 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

tir. 23/12

17:30-11:50

1 stop26h 20m

San Francisco

ons. 7/1

22:54-17:05

2 stops34h 11m

£508

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ons. 21/1

17:35-11:50

1 stop26h 15m

San Francisco

søn. 25/1

14:05-17:00

2 stops18h 55m

£514

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ons. 21/1

17:35-11:50

1 stop26h 15m

San Francisco

søn. 25/1

06:00-08:50

2 stops18h 50m

£515

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ons. 21/1

17:35-16:09

2 stops30h 34m

San Francisco

søn. 25/1

14:05-17:00

2 stops18h 55m

£518

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ons. 21/1

17:35-17:47

2 stops32h 12m

San Francisco

søn. 25/1

08:00-08:50

2 stops16h 50m

£520

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

søn. 1/3

17:45-11:50

1 stop26h 05m

San Francisco

ons. 11/3

22:55-08:05

2 stops26h 10m

£522

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ons. 21/1

09:25-11:50

1 stop34h 25m

San Francisco

søn. 25/1

13:55-17:00

1 stop19h 05m

£524

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

tir. 3/3

08:40-20:57

2 stops20h 17m

San Francisco

søn. 8/3

22:50-08:10

2 stops26h 20m

£527

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ons. 21/1

09:25-23:04

2 stops21h 39m

San Francisco

søn. 25/1

05:45-08:50

2 stops19h 05m

£527

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

lør. 28/2

17:30-11:50

1 stop26h 20m

San Francisco

man. 9/3

14:55-17:00

1 stop19h 05m

£535

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Southampton to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart on your flight to San Francisco is on a Thursday when prices can be found for as low as £596. This is often the case because there is less demand to fly during this day of the week. Flights from Southampton to San Francisco on a Sunday will generally be more expensive and average around £693. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to San Francisco?

Our most recent data shows that the best time of day to fly to San Francisco is in the evening. Flights from Southampton to San Francisco during this time can be as low as £491. Try not to purchase tickets at midday because they tend to be around £985. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Southampton to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Southampton to San Francisco (SOU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to San Francisco

Direct flights

None
There are no direct flights from Southampton to San Francisco. There are no popular flight routes from Southampton to San Francisco.
Search flight deals

  • How far is Southampton Eastleigh to San Francisco by plane?

    A flight from Southampton Eastleigh to San Francisco will travel around 5341.1 mi. By plane, this route typically takes 14h 05m.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to San Francisco Airport?

    Prices for flights from Southampton Eastleigh Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Southampton Eastleigh Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Carmel-by-the-Sea
Santa Clara
Seaside
Big Sur
Rohnert Park
Sunnyvale
San Ramon
South San Francisco
Capitola
Campbell
Palo Alto
Sausalito
San Bruno
Woodland
Santa Cruz
Redwood City
Burlingame
Modesto
Aptos
Fremont

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to San Francisco?

It is quick and easy to find Southampton to San Francisco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Francisco that suits you.

Can I find flights from Southampton to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Southampton which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Southampton to San Francisco?

Once all potential Southampton to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Southampton to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Southampton are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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