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Cheap flights from Southampton to San Francisco from £447

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to San Francisco departing on 30/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Southampton to San Francisco

Cheap return flights

Delta Logo
09:20 - 23:33SOU-SFO
22h 13m2 stops
Delta Logo
00:35 - 08:45SFO-SOU
24h 10m2 stops
£525Delta
Find Deal
Fri, 10 Oct - Sun, 12 Oct
KLM Logo
09:20 - 19:30SOU-SFO
18h 10m2 stops
KLM Logo
13:45 - 08:45SFO-SOU
35h 00m1 stop
£538KLM
Find Deal
Fri, 10 Oct - Mon, 13 Oct
Aer Lingus Logo
16:05 - 16:35SOU-SFO
31h 30m1 stop
Aer Lingus Logo
18:20 - 19:40SFO-SOU
17h 20m1 stop
£554Aer Lingus
Find Deal
Sun, 26 Oct - Sun, 2 Nov
Delta Logo
18:05 - 12:50SOU-SFO
25h 45m1 stop
Delta Logo
05:10 - 07:10SFO-SOU
18h 00m2 stops
£562Delta
Find Deal
Sun, 26 Oct - Sun, 2 Nov
British Airways Logo
09:30 - 15:35SOU-SFO
14h 05m1 stop
British Airways Logo
17:20 - 19:40SFO-SOU
18h 20m1 stop
£580British Airways
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Fri, 5 Dec - Mon, 8 Dec
British Airways Logo
09:30 - 15:35SOU-SFO
14h 05m1 stop
British Airways Logo
17:30 - 20:20SFO-SOU
18h 50m2 stops
£589British Airways
Find Deal
Fri, 5 Dec - Mon, 8 Dec
Aer Lingus Logo
09:40 - 15:55SOU-SFO
14h 15m1 stop
Aer Lingus Logo
17:40 - 19:30SFO-SOU
17h 50m1 stop
£591Aer Lingus
Find Deal
Fri, 10 Oct - Mon, 13 Oct
Virgin Atlantic Logo
18:05 - 00:05SOU-SFO
37h 00m2 stops
Virgin Atlantic Logo
05:30 - 17:25SFO-SOU
27h 55m2 stops
£601Virgin Atlantic
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Sun, 26 Oct - Sun, 2 Nov
Logo
09:40 - 09:30SOU-SFO
31h 50m3 stops
Logo
16:20 - 08:05SFO-SOU
31h 45m3 stops
£872
Find Deal
Fri, 10 Oct - Mon, 13 Oct
Logo
09:40 - 09:30SOU-SFO
31h 50m3 stops
Logo
07:30 - 19:30SFO-SOU
28h 00m2 stops
£907
Find Deal
Fri, 10 Oct - Mon, 13 Oct

Delta flights from Southampton to San Francisco

Our best Delta deals on Southampton to San Francisco flight tickets
Delta
10 Oct
SOU09:20Southampton Eastleigh
22h 13m
2 stops
SFO23:33San Francisco
12 Oct
SFO00:35San Francisco
24h 10m
2 stops
SOU08:45Southampton Eastleigh
£525
Find similar
Delta
26 Oct
SOU18:05Southampton Eastleigh
25h 45m
1 stop
SFO12:50San Francisco
2 Nov
SFO05:10San Francisco
18h 00m
2 stops
SOU07:10Southampton Eastleigh
£562
Find similar
Delta
11 Dec
SOU08:50Southampton Eastleigh
21h 28m
2 stops
SFO22:18San Francisco
29 Dec
SFO07:00San Francisco
17h 10m
2 stops
SOU08:10Southampton Eastleigh
£590
Find similar

KLM flights from Southampton to San Francisco

Our best KLM deals on Southampton to San Francisco flight tickets
KLM
10 Oct
SOU09:20Southampton Eastleigh
18h 10m
2 stops
SFO19:30San Francisco
13 Oct
SFO13:45San Francisco
35h 00m
1 stop
SOU08:45Southampton Eastleigh
£538
Find similar
KLM
25 Oct
SOU09:20Southampton Eastleigh
18h 55m
2 stops
SFO20:15San Francisco
1 Nov
SFO14:55San Francisco
34h 15m
1 stop
SOU08:10Southampton Eastleigh
£600
Find similar
KLM
25 Oct
SOU18:05Southampton Eastleigh
26h 45m
1 stop
SFO12:50San Francisco
1 Nov
SFO14:55San Francisco
34h 15m
1 stop
SOU08:10Southampton Eastleigh
£760
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 12 September 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 10/10

09:20-23:33

2 stops22h 13m

San Francisco

Sun 12/10

00:35-08:45

2 stops24h 10m

£525

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 10/10

09:20-19:30

2 stops18h 10m

San Francisco

Mon 13/10

13:45-08:45

1 stop35h 00m

£538

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 26/10

16:05-16:35

1 stop31h 30m

San Francisco

Sun 2/11

18:20-19:40

1 stop17h 20m

£554

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 26/10

18:05-12:50

1 stop25h 45m

San Francisco

Sun 2/11

05:10-07:10

2 stops18h 00m

£562

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 5/12

09:30-15:35

1 stop14h 05m

San Francisco

Mon 8/12

17:20-19:40

1 stop18h 20m

£580

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 5/12

09:30-15:35

1 stop14h 05m

San Francisco

Mon 8/12

17:30-20:20

2 stops18h 50m

£589

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 10/10

09:40-15:55

1 stop14h 15m

San Francisco

Mon 13/10

17:40-19:30

1 stop17h 50m

£591

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 26/10

18:05-00:05

2 stops37h 00m

San Francisco

Sun 2/11

05:30-17:25

2 stops27h 55m

£601

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 10/10

09:40-09:30

3 stops31h 50m

San Francisco

Mon 13/10

16:20-08:05

3 stops31h 45m

£872

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 10/10

09:40-09:30

3 stops31h 50m

San Francisco

Mon 13/10

07:30-19:30

2 stops28h 00m

£907

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Southampton to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart on your flight to San Francisco is on a Tuesday when prices can be found for as low as £557. This is often the case because there is less demand to fly during this day of the week. Flights from Southampton to San Francisco on a Sunday will generally be more expensive and average around £632. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to San Francisco?

Our most recent data shows that the best time of day to fly to San Francisco is in the evening. Flights from Southampton to San Francisco during this time can be as low as £475. Try not to purchase tickets at midday because they tend to be around £931. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Southampton to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Southampton to San Francisco (SOU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to San Francisco

Direct flights

None
There are no direct flights from Southampton to San Francisco. There are no popular flight routes from Southampton to San Francisco.
Search flight deals

  • How far is Southampton Eastleigh to San Francisco by plane?

    A flight from Southampton Eastleigh to San Francisco will travel around 5341.1 mi. By plane, this route typically takes 14h 05m.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to San Francisco Airport?

    Prices for flights from Southampton Eastleigh Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Southampton Eastleigh Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Carmel-by-the-Sea
Santa Clara
Seaside
Vacaville
Salinas
Rohnert Park
Campbell
Sunnyvale
Milpitas
San Ramon
South San Francisco
Capitola
Sonoma
San Bruno
Sausalito
Millbrae
Santa Cruz
Woodland
Redwood City
Burlingame

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to San Francisco?

It is quick and easy to find Southampton to San Francisco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Francisco that suits you.

Can I find flights from Southampton to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Southampton which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Southampton to San Francisco?

Once all potential Southampton to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Southampton to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Southampton are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organise and travel with friends or family. Trips is free – and available to use no matter where you book.
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