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Cheap flights from Southampton to San Francisco from £524

This is the cheapest return flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to San Francisco departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap return flights

Aer Lingus Logo
09:10 - 15:55SOU-SFO
14h 45m1 stop
Aer Lingus Logo
17:40 - 19:30SFO-SOU
17h 50m1 stop
£524Aer Lingus
Find Deal
Sun, 5 Oct - Sun, 12 Oct
Virgin Atlantic Logo
18:25 - 23:43SOU-SFO
37h 18m2 stops
Virgin Atlantic Logo
15:00 - 08:45SFO-SOU
33h 45m2 stops
£585Virgin Atlantic
Find Deal
Sun, 5 Oct - Sun, 12 Oct
Delta Logo
18:25 - 11:45SOU-SFO
25h 20m1 stop
Delta Logo
09:55 - 17:00SFO-SOU
23h 05m2 stops
£605Delta
Find Deal
Sun, 5 Oct - Sun, 12 Oct
KLM Logo
18:25 - 11:45SOU-SFO
25h 20m1 stop
KLM Logo
15:05 - 17:00SFO-SOU
17h 55m2 stops
£625KLM
Find Deal
Sun, 5 Oct - Sun, 12 Oct
Logo
20:00 - 13:50SOU-SFO
25h 50m2 stops
Logo
17:40 - 08:10SFO-SOU
30h 30m2 stops
£676
Find Deal
Sun, 5 Oct - Sun, 12 Oct
Logo
09:10 - 13:57SOU-SFO
36h 47m3 stops
Logo
10:15 - 19:30SFO-SOU
25h 15m3 stops
£728
Find Deal
Sun, 5 Oct - Sun, 12 Oct
Delta Logo
18:05 - 11:50SOU-SFO
25h 45m1 stop
Delta Logo
07:00 - 08:05SFO-SOU
17h 05m2 stops
£774Delta
Find Deal
Sun, 16 Nov - Thu, 18 Dec
British Airways Logo
09:40 - 15:55SOU-SFO
14h 15m1 stop
British Airways Logo
17:40 - 19:30SFO-SOU
17h 50m1 stop
£784British Airways
Find Deal
Sat, 6 Sep - Thu, 11 Sep
British Airways Logo
08:30 - 18:45SOU-SFO
18h 15m2 stops
British Airways Logo
17:20 - 15:35SFO-SOU
14h 15m1 stop
£829British Airways
Find Deal
Fri, 14 Nov - Sat, 20 Dec
KLM Logo
17:30 - 11:50SOU-SFO
26h 20m1 stop
KLM Logo
13:55 - 08:50SFO-SOU
34h 55m1 stop
£1,072KLM
Find Deal
Sat, 15 Nov - Fri, 19 Dec

Aer Lingus flights from Southampton to San Francisco

Our best Aer Lingus deals on Southampton to San Francisco flight tickets
Aer Lingus
5 Oct
SOU09:10Southampton Eastleigh
14h 45m
1 stop
SFO15:55San Francisco
12 Oct
SFO17:40San Francisco
17h 50m
1 stop
SOU19:30Southampton Eastleigh
£524
Find similar
Aer Lingus
15 Nov
SOU09:30Southampton Eastleigh
14h 05m
1 stop
SFO15:35San Francisco
19 Dec
SFO17:20San Francisco
31h 25m
1 stop
SOU08:45Southampton Eastleigh
£725
Find similar
Aer Lingus
16 Nov
SOU20:10Southampton Eastleigh
27h 25m
1 stop
SFO15:35San Francisco
20 Dec
SFO17:20San Francisco
18h 20m
1 stop
SOU19:40Southampton Eastleigh
£765
Find similar

Delta flights from Southampton to San Francisco

Our best Delta deals on Southampton to San Francisco flight tickets
Delta
5 Oct
SOU18:25Southampton Eastleigh
25h 20m
1 stop
SFO11:45San Francisco
12 Oct
SFO09:55San Francisco
23h 05m
2 stops
SOU17:00Southampton Eastleigh
£605
Find similar
Delta
16 Nov
SOU18:05Southampton Eastleigh
25h 45m
1 stop
SFO11:50San Francisco
18 Dec
SFO07:00San Francisco
17h 05m
2 stops
SOU08:05Southampton Eastleigh
£774
Find similar
Delta
15 Nov
SOU09:25Southampton Eastleigh
19h 22m
2 stops
SFO20:47San Francisco
18 Dec
SFO07:00San Francisco
17h 05m
2 stops
SOU08:05Southampton Eastleigh
£808
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 22 August 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 5/10

09:10-15:55

1 stop14h 45m

San Francisco

Sun 12/10

17:40-19:30

1 stop17h 50m

£524

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 5/10

18:25-23:43

2 stops37h 18m

San Francisco

Sun 12/10

15:00-08:45

2 stops33h 45m

£585

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 5/10

18:25-11:45

1 stop25h 20m

San Francisco

Sun 12/10

09:55-17:00

2 stops23h 05m

£605

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 5/10

18:25-11:45

1 stop25h 20m

San Francisco

Sun 12/10

15:05-17:00

2 stops17h 55m

£625

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 5/10

20:00-13:50

2 stops25h 50m

San Francisco

Sun 12/10

17:40-08:10

2 stops30h 30m

£676

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 5/10

09:10-13:57

3 stops36h 47m

San Francisco

Sun 12/10

10:15-19:30

3 stops25h 15m

£728

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 16/11

18:05-11:50

1 stop25h 45m

San Francisco

Thu 18/12

07:00-08:05

2 stops17h 05m

£774

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 6/9

09:40-15:55

1 stop14h 15m

San Francisco

Thu 11/9

17:40-19:30

1 stop17h 50m

£784

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 14/11

08:30-18:45

2 stops18h 15m

San Francisco

Sat 20/12

17:20-15:35

1 stop14h 15m

£829

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 15/11

17:30-11:50

1 stop26h 20m

San Francisco

Fri 19/12

13:55-08:50

1 stop34h 55m

£1,072

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Southampton to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart on your flight to San Francisco is on a Tuesday when prices can be found for as low as £557. This is often the case because there is less demand to fly during this day of the week. Flights from Southampton to San Francisco on a Sunday will generally be more expensive and average around £631. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to San Francisco?

Our most recent data shows that the best time of day to fly to San Francisco is in the evening. Flights from Southampton to San Francisco during this time can be as low as £479. Try not to purchase tickets at midday because they tend to be around £937. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Southampton to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Southampton to San Francisco (SOU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to San Francisco

Direct flights

None
There are no direct flights from Southampton to San Francisco. There are no popular flight routes from Southampton to San Francisco.
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  • How far is Southampton Eastleigh to San Francisco by plane?

    A flight from Southampton Eastleigh to San Francisco will travel around 5341.1 mi. By plane, this route typically takes 14h 05m.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to San Francisco Airport?

    Prices for flights from Southampton Eastleigh Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Southampton Eastleigh Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Carmel-by-the-Sea
Santa Clara
Seaside
Vacaville
Salinas
Calistoga
Rohnert Park
Campbell
Sunnyvale
Milpitas
San Ramon
South San Francisco
Brentwood
Capitola
Sonoma
Millbrae
San Bruno
Sausalito
Woodland
Santa Cruz

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to San Francisco?

It is quick and easy to find Southampton to San Francisco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Francisco that suits you.

Can I find flights from Southampton to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Southampton which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Southampton to San Francisco?

Once all potential Southampton to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Southampton to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Southampton are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organise and travel with friends or family. Trips is free – and available to use no matter where you book.
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