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Cheap flights from Southampton to San Francisco from £476

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to San Francisco departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap return flights

Enter your travel dates to find the best prices.
Delta Logo
17:35 - 11:50SOU-SFO
26h 15m1 stop
Delta Logo
22:55 - 08:50SFO-SOU
25h 55m2 stops
£495Delta
Find Deal
Mon, 12 Jan - Sat, 17 Jan
Delta Logo
17:35 - 17:43SOU-SFO
32h 08m2 stops
Delta Logo
22:55 - 08:50SFO-SOU
25h 55m2 stops
£499Delta
Find Deal
Mon, 12 Jan - Sat, 17 Jan
Virgin Atlantic Logo
08:40 - 20:21SOU-SFO
42h 41m2 stops
Virgin Atlantic Logo
11:30 - 08:45SFO-SOU
37h 15m2 stops
£502Virgin Atlantic
Find Deal
Fri, 27 Mar - Tue, 31 Mar
Delta Logo
08:40 - 10:30SOU-SFO
32h 50m2 stops
Delta Logo
12:00 - 17:00SFO-SOU
21h 00m2 stops
£508Delta
Find Deal
Fri, 27 Mar - Tue, 31 Mar
Virgin Atlantic Logo
08:40 - 12:50SOU-SFO
35h 10m1 stop
Virgin Atlantic Logo
13:45 - 08:45SFO-SOU
35h 00m1 stop
£513Virgin Atlantic
Find Deal
Fri, 27 Mar - Tue, 31 Mar
Virgin Atlantic Logo
08:40 - 12:50SOU-SFO
35h 10m1 stop
Virgin Atlantic Logo
13:45 - 08:45SFO-SOU
35h 00m1 stop
£530Virgin Atlantic
Find Deal
Fri, 27 Mar - Tue, 31 Mar
KLM Logo
18:05 - 11:50SOU-SFO
25h 45m1 stop
KLM Logo
13:55 - 08:50SFO-SOU
34h 55m1 stop
£947KLM
Find Deal
Sun, 28 Dec - Sun, 4 Jan
Virgin Atlantic Logo
17:30 - 11:50SOU-SFO
26h 20m1 stop
Virgin Atlantic Logo
13:55 - 17:25SFO-SOU
19h 30m1 stop
£986Virgin Atlantic
Find Deal
Sat, 27 Dec - Sat, 3 Jan
Virgin Atlantic Logo
09:25 - 11:50SOU-SFO
34h 25m1 stop
Virgin Atlantic Logo
19:20 - 08:50SFO-SOU
53h 30m2 stops
£1,011Virgin Atlantic
Find Deal
Sat, 27 Dec - Sat, 3 Jan
British Airways Logo
19:55 - 18:45SOU-SFO
30h 50m2 stops
British Airways Logo
18:20 - 19:40SFO-SOU
17h 20m1 stop
£1,049British Airways
Find Deal
Thu, 11 Dec - Sun, 21 Dec

Delta flights from Southampton to San Francisco

Our best Delta deals on Southampton to San Francisco flight tickets
Delta
12 Jan
SOU17:35Southampton Eastleigh
26h 15m
1 stop
SFO11:50San Francisco
17 Jan
SFO22:55San Francisco
25h 55m
2 stops
SOU08:50Southampton Eastleigh
£495
Find similar
Delta
12 Jan
SOU17:35Southampton Eastleigh
32h 08m
2 stops
SFO17:43San Francisco
17 Jan
SFO22:55San Francisco
25h 55m
2 stops
SOU08:50Southampton Eastleigh
£499
Find similar
Delta
27 Mar
SOU08:40Southampton Eastleigh
32h 50m
2 stops
SFO10:30San Francisco
31 Mar
SFO12:00San Francisco
21h 00m
2 stops
SOU17:00Southampton Eastleigh
£508
Find similar

Virgin Atlantic flights from Southampton to San Francisco

Our best Virgin Atlantic deals on Southampton to San Francisco flight tickets
Virgin Atlantic
27 Mar
SOU08:40Southampton Eastleigh
42h 41m
2 stops
SFO20:21San Francisco
31 Mar
SFO13:45San Francisco
35h 00m
1 stop
SOU08:45Southampton Eastleigh
£502
Find similar
Virgin Atlantic
27 Mar
SOU08:40Southampton Eastleigh
35h 10m
1 stop
SFO12:50San Francisco
31 Mar
SFO13:45San Francisco
35h 00m
1 stop
SOU08:45Southampton Eastleigh
£513
Find similar
Virgin Atlantic
27 Mar
SOU08:40Southampton Eastleigh
35h 10m
1 stop
SFO12:50San Francisco
31 Mar
SFO13:45San Francisco
35h 00m
1 stop
SOU08:45Southampton Eastleigh
£530
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 14 November 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 12/1

17:35-11:50

1 stop26h 15m

San Francisco

Sat 17/1

22:55-08:50

2 stops25h 55m

£495

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 12/1

17:35-17:43

2 stops32h 08m

San Francisco

Sat 17/1

22:55-08:50

2 stops25h 55m

£499

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 27/3

08:40-20:21

2 stops42h 41m

San Francisco

Tue 31/3

11:30-08:45

2 stops37h 15m

£502

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 27/3

08:40-10:30

2 stops32h 50m

San Francisco

Tue 31/3

12:00-17:00

2 stops21h 00m

£508

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 27/3

08:40-12:50

1 stop35h 10m

San Francisco

Tue 31/3

13:45-08:45

1 stop35h 00m

£513

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 27/3

08:40-12:50

1 stop35h 10m

San Francisco

Tue 31/3

13:45-08:45

1 stop35h 00m

£530

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 28/12

18:05-11:50

1 stop25h 45m

San Francisco

Sun 4/1

13:55-08:50

1 stop34h 55m

£947

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 27/12

17:30-11:50

1 stop26h 20m

San Francisco

Sat 3/1

13:55-17:25

1 stop19h 30m

£986

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 27/12

09:25-11:50

1 stop34h 25m

San Francisco

Sat 3/1

19:20-08:50

2 stops53h 30m

£1,011

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 11/12

19:55-18:45

2 stops30h 50m

San Francisco

Sun 21/12

18:20-19:40

1 stop17h 20m

£1,049

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Southampton to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart on your flight to San Francisco is on a Thursday when prices can be found for as low as £593. This is often the case because there is less demand to fly during this day of the week. Flights from Southampton to San Francisco on a Sunday will generally be more expensive and average around £690. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to San Francisco?

Our most recent data shows that the best time of day to fly to San Francisco is in the evening. Flights from Southampton to San Francisco during this time can be as low as £489. Try not to purchase tickets at midday because they tend to be around £981. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Southampton to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Southampton to San Francisco (SOU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to San Francisco

Direct flights

None
There are no direct flights from Southampton to San Francisco. There are no popular flight routes from Southampton to San Francisco.
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  • How far is Southampton Eastleigh to San Francisco by plane?

    A flight from Southampton Eastleigh to San Francisco will travel around 5341.1 mi. By plane, this route typically takes 14h 05m.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to San Francisco Airport?

    Prices for flights from Southampton Eastleigh Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Southampton Eastleigh Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Carmel-by-the-Sea
Santa Clara
Seaside
Big Sur
Rohnert Park
Sunnyvale
San Ramon
South San Francisco
Capitola
Campbell
Palo Alto
Sausalito
San Bruno
Woodland
Santa Cruz
Redwood City
Burlingame
Modesto
Aptos
Fremont

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to San Francisco?

It is quick and easy to find Southampton to San Francisco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Francisco that suits you.

Can I find flights from Southampton to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Southampton which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Southampton to San Francisco?

Once all potential Southampton to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Southampton to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Southampton are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organise and travel with friends or family. Trips is free – and available to use no matter where you book.
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