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Cheap flights from Southampton to San Francisco from £388

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Southampton to San Francisco departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags
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Find the cheapest flights from Southampton to San Francisco

Cheap return flights

Enter your travel dates to find the best prices.
British Airways Logo
09:30 - 15:35
SOU
-
SFO
14h 05m
1 stop
British Airways Logo
19:20 - 19:40
SFO
-
SOU
17h 20m
1 stop
£499British Airways
Mon, 23 Feb - Sun, 8 Mar
British Airways Logo
16:05 - 15:35
SOU
-
SFO
31h 30m
1 stop
British Airways Logo
18:20 - 15:35
SFO
-
SOU
14h 15m
1 stop
£505British Airways
Tue, 24 Feb - Tue, 10 Mar
KLM Logo
08:50 - 12:50
SOU
-
SFO
35h 00m
1 stop
KLM Logo
14:55 - 08:20
SFO
-
SOU
34h 25m
1 stop
£507KLM
Wed, 11 Mar - Wed, 18 Mar
British Airways Logo
09:30 - 15:35
SOU
-
SFO
14h 05m
1 stop
British Airways Logo
18:20 - 08:45
SFO
-
SOU
31h 25m
1 stop
£510British Airways
Mon, 23 Feb - Sat, 14 Mar
British Airways Logo
09:30 - 15:35
SOU
-
SFO
14h 05m
1 stop
British Airways Logo
18:20 - 19:40
SFO
-
SOU
18h 20m
1 stop
£511British Airways
Sat, 28 Feb - Wed, 11 Mar
KLM Logo
17:35 - 12:50
SOU
-
SFO
26h 15m
1 stop
KLM Logo
07:00 - 08:20
SFO
-
SOU
18h 20m
2 stops
£515KLM
Wed, 11 Mar - Wed, 18 Mar
British Airways Logo
16:05 - 15:35
SOU
-
SFO
31h 30m
1 stop
British Airways Logo
18:20 - 08:45
SFO
-
SOU
31h 25m
1 stop
£515British Airways
Tue, 24 Feb - Sat, 14 Mar
British Airways Logo
09:30 - 15:35
SOU
-
SFO
14h 05m
1 stop
British Airways Logo
18:20 - 08:45
SFO
-
SOU
31h 25m
1 stop
£516British Airways
Sat, 28 Feb - Sat, 14 Mar
British Airways Logo
09:30 - 15:35
SOU
-
SFO
14h 05m
1 stop
British Airways Logo
18:20 - 08:45
SFO
-
SOU
31h 25m
1 stop
£517British Airways
Mon, 23 Feb - Fri, 13 Mar
KLM Logo
08:50 - 23:15
SOU
-
SFO
21h 25m
2 stops
KLM Logo
09:15 - 08:20
SFO
-
SOU
16h 05m
2 stops
£518KLM
Wed, 11 Mar - Wed, 18 Mar

British Airways flights from Southampton to San Francisco

Our best British Airways deals on Southampton to San Francisco flight tickets
British Airways
23 Feb
SOU09:30Southampton Eastleigh
14h 05m
1 stop
SFO15:35San Francisco
9 Mar
SFO18:20San Francisco
14h 15m
1 stop
SOU15:35Southampton Eastleigh
£499
British Airways
24 Feb
SOU16:05Southampton Eastleigh
31h 30m
1 stop
SFO15:35San Francisco
9 Mar
SFO18:20San Francisco
14h 15m
1 stop
SOU15:35Southampton Eastleigh
£505
British Airways
23 Feb
SOU09:30Southampton Eastleigh
14h 05m
1 stop
SFO15:35San Francisco
14 Mar
SFO18:20San Francisco
31h 25m
1 stop
SOU08:45Southampton Eastleigh
£510

KLM flights from Southampton to San Francisco

Our best KLM deals on Southampton to San Francisco flight tickets
KLM
11 Mar
SOU17:35Southampton Eastleigh
26h 15m
1 stop
SFO12:50San Francisco
18 Mar
SFO07:00San Francisco
18h 20m
2 stops
SOU08:20Southampton Eastleigh
£515
KLM
11 Mar
SOU08:50Southampton Eastleigh
19h 09m
2 stops
SFO20:59San Francisco
18 Mar
SFO09:15San Francisco
16h 05m
2 stops
SOU08:20Southampton Eastleigh
£519
KLM
12 Mar
SOU18:05Southampton Eastleigh
25h 45m
1 stop
SFO12:50San Francisco
19 Mar
SFO09:15San Francisco
16h 05m
2 stops
SOU08:20Southampton Eastleigh
£521

momondo Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 279,928 searches. Data last updated 28 January 2026.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 23/2

09:30-15:35

1 stop14h 05m

San Francisco

Sun 8/3

19:20-19:40

1 stop17h 20m

£499

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 24/2

16:05-15:35

1 stop31h 30m

San Francisco

Tue 10/3

18:20-15:35

1 stop14h 15m

£505

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 11/3

08:50-12:50

1 stop35h 00m

San Francisco

Wed 18/3

14:55-08:20

1 stop34h 25m

£507

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 23/2

09:30-15:35

1 stop14h 05m

San Francisco

Sat 14/3

18:20-08:45

1 stop31h 25m

£510

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 28/2

09:30-15:35

1 stop14h 05m

San Francisco

Wed 11/3

18:20-19:40

1 stop18h 20m

£511

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 11/3

17:35-12:50

1 stop26h 15m

San Francisco

Wed 18/3

07:00-08:20

2 stops18h 20m

£515

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 24/2

16:05-15:35

1 stop31h 30m

San Francisco

Sat 14/3

18:20-08:45

1 stop31h 25m

£515

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 28/2

09:30-15:35

1 stop14h 05m

San Francisco

Sat 14/3

18:20-08:45

1 stop31h 25m

£516

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 23/2

09:30-15:35

1 stop14h 05m

San Francisco

Fri 13/3

18:20-08:45

1 stop31h 25m

£517

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 11/3

08:50-23:15

2 stops21h 25m

San Francisco

Wed 18/3

09:15-08:20

2 stops16h 05m

£518

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Southampton to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart on your flight to San Francisco is on a Thursday when prices can be found for as low as £555. This is often the case because there is less demand to fly during this day of the week. Flights from Southampton to San Francisco on a Sunday will generally be more expensive and average around £657. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to San Francisco?

Our most recent data shows that the best time of day to fly to San Francisco is in the morning. Flights from Southampton to San Francisco during this time can be as low as £551. Try not to purchase tickets at midday because they tend to be around £845. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Southampton to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Southampton to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Southampton to San Francisco (SOU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Southampton to San Francisco

Fastest flight time

14h 05m

Direct flights

None
The fastest flight from Southampton to San Francisco takes 14h 05m
There are no direct flights from Southampton to San Francisco. There are no popular flight routes from Southampton to San Francisco.
Search flight deals

  • How far is Southampton Eastleigh to San Francisco by plane?

    A flight from Southampton Eastleigh to San Francisco will travel around 5341.1 mi. By plane, this route typically takes 14h 05m.

  • When did momondo last update prices for flights from Southampton Eastleigh Airport to San Francisco Airport?

    Prices for flights from Southampton Eastleigh Airport to San Francisco Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Southampton Eastleigh Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Southampton Eastleigh Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Sunnyvale
Santa Clara
Seaside
Big Sur
Rohnert Park
Campbell
Palo Alto
Santa Cruz
Roseville
Novato
South San Francisco
Capitola
Aptos
Sausalito
San Bruno
Woodland
Redwood City
Pacific Grove
Mill Valley
Burlingame

Why use momondo?

Why should I use momondo to find a flight deal from Southampton to San Francisco?

It is quick and easy to find Southampton to San Francisco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Francisco that suits you.

Can I find flights from Southampton to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Southampton which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Southampton to San Francisco?

Once all potential Southampton to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Southampton to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Southampton are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organise and travel with friends or family. Trips is free – and available to use no matter where you book.
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